Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Organic Broccoli Sprout Powder Ingredients & Drug Interactions

by Health Ranger Select

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Organic Broccoli Sprout Powder is a dietary supplement by Health Ranger Select with 4 active ingredients. Its ingredients are commonly taken for antioxidant support, general cellular health, detoxification support.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sulforaphane, organic Broccoli sprout powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Organic Broccoli Sprout Powder by Health Ranger Select

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains 4 active ingredients: glucoraphanin, sulforaphane, broccoli sprout powder, and glucosinolates. Sulforaphane and glucoraphanin are compounds found naturally in broccoli sprouts that may support cellular health.

Glucosinolates are sulfur-containing compounds in broccoli that break down into sulforaphane when the plant is chewed or processed. The product has no inactive fillers or other ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: fight aging and reduce oxidative stress.
  • We looked for evidence on: Exercise-induced muscle damage, Exercise-induced muscle soreness, Sunburn, cellular senescence, oxidative damage.
  • The closest evidence on file: Sulforaphane is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Sulforaphane is rated "Insufficient Reliable Evidence To Rate" for Sunburn, Exercise-induced muscle damage.

For sulforaphane, the data show it is possibly effective for prostate cancer, though it is possibly ineffective for Helicobacter pylori (a stomach bacterium) and the evidence is insufficient to rate it for hay fever, asthma, or cancer broadly. For broccoli, it is possibly effective for colorectal cancer, but evidence is insufficient to rate it for bladder cancer, breast cancer, fibromyalgia, or gastric cancer.

The evidence for these specific conditions is not well established across the board.

The evidence, ingredient by ingredient Sulforaphane Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulforaphane from food is generally well tolerated, but concentrated supplements have been less studied for long-term safety. Adverse effects reported in trials include bowel discomfort, heartburn, stomach upset, vomiting, headache, insomnia, irritability, and weight gain (an average of 4 pounds over 18 weeks in one autism study); rare cases of seizure have been reported.

Broccoli as food is safe, but concentrated extracts are less studied; oral use has caused loose stools, diarrhea, abdominal pain, and cramping, especially at higher doses. Concentrated supplements have not been proven safe in pregnancy — stick to normal food amounts.

There is not enough information on supplement-level doses while breastfeeding; use caution and prefer dietary amounts instead.

Side effects, ingredient by ingredient Sulforaphane Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Sulforaphane, Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 724 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take medications metabolized by CYP1A2, CYP3A4, CYP2E1, or CYP2A6 enzymes — a large group of common drugs. Sulforaphane may inhibit some of these enzymes (potentially raising drug levels), while broccoli may speed up others (potentially lowering drug levels).

The net effect depends on your individual medications and how much of this product you take.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may support prostate health, but the evidence for most other conditions is limited or absent. If you take any medications — especially those processed by your liver — you should check them against this product's interactions before starting.

Talk with your doctor or pharmacist, particularly if you're pregnant, breastfeeding, or have a history of seizures.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Broccoli Sprout Powder, straight from the product label.

Brand Health Ranger Select
Barcode (UPC) 050742582210
Net contents 4 Ounce(s); 113 Gram(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 257624
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Broccoli Sprout Powder by Health Ranger Select, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
37
UPC/BARCODE
050742582210
IngredientAmount% DV
Glucoraphanin115794 mcg--
Sulforaphane44997 mcg--
organic Broccoli sprout powder3000 mg--
Glucosinolates99900 mcg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Looking for a tremendous nutritional boost?

Formula

Health Ranger Select Organic Broccoli Sprout Powder condenses the power of nutrient-rich broccoli sprouts to bring you high levels of sulforaphane, glucosinolates, and glucoraphanin -- all essential to fight aging, reduce oxidative stress, and fuel your body with the best nutrition possible. Sprouts contain far more condensed nutrients than broccoli, so organic broccoli sprout powder is the perfect choice.

K Natural Food Certifiers (Kosher)

Suggested/Recommended/Usage/Directions

Just stir into your juice, smoothie, or salad and enjoy!

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Certified Organic by Natural Food Certifiers, Inc.

Gluten free

Vegan

GMO Guard Natural Food Certifiers

Seals/Symbols

Laboratory Verified

K Natural Food Certifiers (Kosher) USDA Organic

Glyphosate tested

Precautions

Manufactured in a facility which may contain nuts (peanuts, tree nuts).

See for yourself

Organic Broccoli Sprout Powder by Health Ranger Select label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic Broccoli Sprout Powder by Health Ranger Select

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container37 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glucoraphanin

115794 mcg per serving

Sulforaphane

Interacts with
722 drugs
44997 mcg per serving

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effec...

Sulforaphane monograph & interactions

Organic Broccoli sprout powder

Interacts with
187 drugs
3000 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Organic Broccoli sprout powder monograph & interactions

Glucosinolates

99900 mcg per serving
Interaction report

Organic Broccoli Sprout Powder by Health Ranger Select Drug Interactions

Want to check YOUR meds against Organic Broccoli Sprout Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
723Drugs
723 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Broccoli Sprout Powder with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sulforaphane3 drug types · 722 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP1A2 enzyme activity. However, its precursor glucoraphanin also appears to increase the expression of the CYP1A2 enzyme, which could lead to increased metabolism of CYP1A2 substrates. These effects have not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
In vitro evidence shows that sulforaphane inhibits CYP2E1 enzymes. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP3A4 enzyme activity and downregulates its expression. This interaction has not been reported in humans.

Likelihood Possible Evidence D

organic Broccoli sprout powder2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Organic Broccoli Sprout Powder, from the product label.

Health Ranger Select

See all Health Ranger Select products
Name
Health Ranger Store
Street Address
3820 Central Ave. #109
City
Cheyenne
State
WY
ZipCode
82001
Phone Number
1-888-959-6415
Web Address
healthrangerstore.com
Pharmacist Counseling Corner

Organic Broccoli Sprout Powder by Health Ranger Select: Common Questions

Does Organic Broccoli Sprout Powder by Health Ranger Select interact with any medications?
Yes. Based on its ingredients, Organic Broccoli Sprout Powder has a known interaction with 723 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Broccoli Sprout Powder contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work for cancer prevention?
The evidence shows broccoli sprout powder is possibly effective for colorectal cancer. For other cancers — breast, bladder, gastric — the evidence is insufficient to rate it. Talk with your doctor about whether this fits into your care plan.
Is it safe to take while pregnant?
Concentrated sulforaphane supplements have not been proven safe in pregnancy, so the data advise against them. Stick to normal dietary amounts of broccoli instead, and discuss with your doctor or pharmacist.
Can I take this while breastfeeding?
There isn't enough information on supplement-level doses while breastfeeding. Use caution, prefer dietary amounts, and talk with your doctor or pharmacist for personalized advice.
What side effects should I watch for?
Stomach upset, heartburn, loose stools, and abdominal cramping are the most common, especially at higher doses. Headache, insomnia, and weight gain have also been reported in trials. Stop and talk with your doctor if you experience new symptoms.
Why is there no filler list?
This product contains no inactive ingredients — just the four active plant compounds. Everything in it is the active ingredient itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Broccoli Sprout Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Broccoli Sprout Powder label
Sources

Sources & How We Checked

Organic Broccoli Sprout Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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