Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Organic Centella/Gotu Kola Ingredients & Drug Interactions

by Herbadiet

Organic Centella/Gotu Kola label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Centella/Gotu Kola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Centella/Gotu Kola is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Centella asiatica leaf powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Centella/Gotu Kola by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Centella/Gotu Kola by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Centella/Gotu Kola by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: organic Centella asiatica leaf powder, commonly called gotu kola. It's a traditional herb used in Asian medicine that some people take for circulation problems and skin healing.

The powder form means you're getting the whole leaf material with no added fillers or binders.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Supports cognitive functions.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD), Memory, Mental clarity, Brain health.
  • The closest evidence on file: Gotu Kola is rated "Possibly Ineffective" for Cognitive function (Natural Medicines).
  • Also on file: Gotu Kola is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD).

The evidence for gotu kola is mixed. It's possibly effective for venous insufficiency (sluggish circulation in the legs) and may help with minor burns.

For radiation dermatitis (skin damage from cancer treatment), the evidence suggests it probably doesn't work. For brain and cognitive health — including Alzheimer's disease and generalized anxiety — there simply isn't enough reliable evidence to know whether it helps.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated when taken by mouth or applied to skin in the short term, but the quality of safety data is limited. The most common side effects are mild: stomach irritation and nausea by mouth, and a rash-like reaction called eczema when applied topically.

Liver toxicity is rare but has been reported — there's concern it may affect liver function in some people, though we can't be certain from the cases on record. Because of those liver concerns, safety during pregnancy and breastfeeding hasn't been well studied — the facts show it's possibly safe in pregnancy but safety during breastfeeding is unknown, so talk with your doctor or pharmacist before use if you're pregnant or nursing.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before adding this if you take any CNS depressants — sleep aids, anti-anxiety drugs, opioids, or anything else that makes you drowsy — because gotu kola may increase sedation. Also double-check if you're on any medication known to stress the liver (your pharmacist can tell you which ones apply to you).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu kola may help with circulation issues and wound healing, but the science is modest. If you take sedating medications or drugs that stress your liver, you'll need to clear it with your doctor or pharmacist first — the interactions are real and worth checking.

Otherwise, if you're generally healthy and not on interacting medications, short-term use is typically tolerated well. Talk it over with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Centella/Gotu Kola, straight from the product label.

Brand Herbadiet
Net contents 0 Not Present
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243623
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Centella/Gotu Kola by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Gram(s)
Maximum serving Sizes:
4 Gram(s)
IngredientAmount% DV
organic Centella asiatica leaf powder2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Certified organic herb powder

Supports cognitive functions

Free of: fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

V vegan

Ethically sourced Scientifically tested Premium grade ingredients

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement take up to 4 gm, or as directed by your physician.

Precautions

Keep out of reach of children.

Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

FDA Disclaimer Statement

Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Batch No. ARK-P94

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Centella/Gotu Kola by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Centella/Gotu Kola label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Centella/Gotu Kola by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Gram(s) Dosage formPowder Amounts shown are per serving.

Organic Centella asiatica leaf powder

Interacts with
579 drugs
2 Gram(s) per serving

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Organic Centella asiatica leaf powder monograph & interactions
Interaction report

Organic Centella/Gotu Kola by Herbadiet Drug Interactions

Want to check YOUR meds against Organic Centella/Gotu Kola?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

organic Centella asiatica leaf powder 579

Individual Drug Interactions

The ingredients in Organic Centella/Gotu Kola interact with 579 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Centella/Gotu Kola interact with drugs. Each result below shows which ingredient is responsible. organic Centella asiatica leaf powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Centella/Gotu Kola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Centella asiatica leaf powder2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
organic Centella asiatica leaf powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Centella/Gotu Kola, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Organic Centella/Gotu Kola by Herbadiet: Common Questions

Does Organic Centella/Gotu Kola by Herbadiet interact with any medications?
Yes. Based on its ingredients, Organic Centella/Gotu Kola has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Centella/Gotu Kola contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does gotu kola actually work for anxiety?
There isn't enough reliable evidence to know. While some people use it for generalized anxiety, the studies we have aren't strong enough to say whether it really helps. If anxiety is a concern, talk with your doctor about proven treatments.
What are the most common side effects?
Taking it by mouth, most people experience mild stomach irritation or nausea if anything. Applied to skin, it can sometimes trigger a rash. Serious problems like liver damage are rare.
Can I take this if I'm pregnant?
The data suggests it's possibly safe in pregnancy, but safety hasn't been well studied and it was traditionally avoided. Talk with your doctor or pharmacist about whether it's right for you during pregnancy — that's a personal decision based on your whole health picture.
Is it safe to use while breastfeeding?
Safety during breastfeeding is unknown, so it's best avoided. Check with your doctor or pharmacist if you're nursing and thinking about using it.
Can gotu kola hurt my liver?
Liver toxicity is rare but has been reported. In one clinical trial at a standard dose, liver function stayed normal over six months, so the risk may be dose-dependent and product-dependent. If you have liver problems or take other drugs that affect the liver, definitely talk to your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Centella/Gotu Kola is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Centella/Gotu Kola label
Go deeper

The Full Monographs Behind Organic Centella/Gotu Kola’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Sources

Sources & How We Checked

Organic Centella/Gotu Kola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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