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Dietary supplement

Organic Flax Seed Oil Ingredients & Drug Interactions

by VitalBulk

Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Organic Flax Seed Oil is a dietary supplement by VitalBulk with 1 active ingredient. Its ingredients are commonly taken for source of omega-3 (ala) fatty acids, heart and cholesterol health, dry skin and inflammation.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Flax seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Organic Flax Seed Oil by VitalBulk

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

VitalBulk's Organic Flax Seed Oil is a liquid supplement with 3 ingredients: polyunsaturated fat, monounsaturated fat, and organic flax seed oil itself. The flax seed oil is where the active compounds live — chiefly alpha-linolenic acid (ALA), an omega-3 fat your body can convert to other beneficial forms.

The other two are the fats naturally present in flax. There are no inactive fillers or binders listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Flaxseed Oil product and its label doesn't state a use — see Flaxseed Oil's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for flax seed oil is limited. Our data shows it's possibly ineffective for obesity, rheumatoid arthritis (RA), bipolar disorder, and high cholesterol (hyperlipidemia).

That means controlled trials haven't found solid proof it works for these conditions — not that it definitely doesn't, just that the case isn't there yet.

The evidence, ingredient by ingredient Flaxseed Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Flax seed oil is generally well tolerated when taken by mouth. A small number of people report changes in bowel habits, dry mouth, or indigestion at typical doses around 5 grams daily.

Higher doses — 30 grams a day or more — are linked to loose stools and diarrhea. Rare severe allergic reactions like anaphylaxis have been reported.

Safety data during pregnancy and breastfeeding is limited. Pregnancy is rated possibly safe, but lactation data isn't established.

Talk with your doctor or pharmacist before use if you're pregnant or nursing, since quality and dose can vary between products.

Side effects, ingredient by ingredient Flaxseed Oil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Flaxseed Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check it with your doctor or pharmacist if you're on blood thinners (anticoagulants or antiplatelets like warfarin or aspirin) — flaxseed oil may increase bleeding risk. Blood pressure medications (antihypertensives) are next — it may lower your pressure further.

And if you take ezetimibe (Zetia), flaxseed oil will block its absorption.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Flax seed oil may be worth considering if you're looking for an omega-3 supplement, though the evidence it works for specific conditions is weak. If you take blood thinners, blood pressure drugs, or ezetimibe, you need to clear this with your doctor or pharmacist first — the interaction risks are real.

Pregnancy and breastfeeding? Check with your own healthcare provider, since the safety picture isn't complete.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Flax Seed Oil, straight from the product label.

Brand VitalBulk
Net contents 0 Not Present
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 233477
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Flax Seed Oil by VitalBulk, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
14 Gram(s)
Maximum serving Sizes:
14 Gram(s)
Servings per container
63
IngredientAmount% DV
Calories126 Calorie(s)6%
Saturated Fat2 Gram(s)10%
Total Fat14 Gram(s)22%
Polyunsaturated Fat10 Gram(s)--
Monounsaturated Fat3 Gram(s)--
organic Flax seed Oil15 mL--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Oil

Solvent free

Naturally preserved with inert nitrogen gas

Natural product, may vary in taste and color.

Tested gluten free Certified nonGE naturally

FDA Statement of Identity

Food/Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) tablespoon with food up to six times daily, or as directed by your health care practitioner.

Precautions

Keep out of reach of children in a cool, dry place.

Food supplements should not be used as a substitute for a varied diet.

In case of adverse event: 855-885-2855

Storage

Keep out of reach of children in a cool, dry place.

Seals/Symbols

Tested gluten free Certified nonGE naturally

See for yourself

Organic Flax Seed Oil by VitalBulk label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic Flax Seed Oil by VitalBulk

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size14 Gram(s) Dosage formLiquid Servings per container63 Amounts shown are per serving.

Organic Flax seed Oil

Interacts with
293 drugs
15 mL per serving

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help s...

Organic Flax seed Oil monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Flax Seed Oil by VitalBulk Drug Interactions

Want to check YOUR meds against Organic Flax Seed Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Flax Seed Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Flax seed Oil3 drug types · 293 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.

Likelihood Possible Evidence D
Ezetimibe (Zetia)

Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Organic Flax Seed Oil, from the product label.

VitalBulk

See all VitalBulk products
Name
VitalBulk Inc.
Street Address
294 Anna St.
City
Watsonville
State
CA
ZipCode
95076
Phone Number
855-885-2855
Pharmacist Counseling Corner

Organic Flax Seed Oil by VitalBulk: Common Questions

Does Organic Flax Seed Oil by VitalBulk interact with any medications?
Yes. Based on its ingredients, Organic Flax Seed Oil has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Flax Seed Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Pregnancy is rated possibly safe, but safety data is limited. Talk with your doctor before starting it — they know your full picture and can give you personalized advice.
Is it safe to breastfeed while taking flax seed oil?
Safety information during breastfeeding isn't established. Use it only if your doctor advises it.
What side effects should I watch for?
Most people tolerate it well. A small number report changes in bowel habits, dry mouth, or indigestion at normal doses. Higher doses can cause loose stools and diarrhea. Severe allergic reactions are rare but possible.
Does flax seed oil actually work for high cholesterol?
Our data shows it's possibly ineffective for high cholesterol (hyperlipidemia). Controlled trials haven't confirmed it lowers cholesterol.
What does the flax seed oil actually do in this product?
It's the active ingredient — it contains alpha-linolenic acid (ALA), an omega-3 fat your body can use. The polyunsaturated and monounsaturated fats are naturally present in flax as well.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Flax Seed Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Flax Seed Oil label
Sources

Sources & How We Checked

Organic Flax Seed Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Flaxseed Oil 21 references
  1. Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
  2. Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
  3. Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
  4. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
  5. Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
  6. Bloedon LT, Szapary PO. Flaxseed and cardiovascular risk. Nutr Rev 2004;62:18-27. DOI
  7. Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
  8. Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
  9. Paschos GK, Magkos F, Panagiotakos DB, et al. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients. Eur J Clin Nutr 2007;61:1201-6. PubMed
  10. Harper CR, Edwards MC, Jacobson TA. Flaxseed oil supplementation does not affect plasma lipoprotein concentration or particle size in human subjects. J Nutr 2006;136:2844-8. PubMed
  11. University of Montreal. Pregnant Women Consuming Flaxseed Oil Have High Risk Of Premature Birth.ScienceDaily, October 29, 2008. Available at: www.sciencedaily.com/releases/2008/10/081027140817.htm (Accessed May 14, 2009).
  12. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Eur.J Clin.Nutr. 1995;49(3):169-178.
  13. Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. Effects of flaxseed supplements on blood pressure: a systematic review and meta-analysis of controlled clinical trial. Clin Nutr. 2016 Jun;3 PubMed
  14. Taghizadeh M, Jamilian M, Mazloomi M, Sanami M, Asemi Z. A randomized-controlled clinical trial investigating the effect of omega-3 fatty acids on vitamin E co-supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes. J
  15. Blackwood DP, LaVallee RK, Al Busaidi A, Jassal DS, Pierce GN. A randomized trial of the effects of ezetimibe on the absorption of omega-3 fatty acids in cardiac disease patients: a pilot study. Clin Nutr ESPEN. 2015 Oct;10(5):e155-e159. PubMed
  16. Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. Effects of flaxseed and flaxseed oil supplement on serum levels of inflammatory markers, metabolic parameters and severity of disease in patients with ulcerative colitis. Complement Ther Med. 2019;46:36-43. PubMed
  17. Downie LE, Hom MM, Berdy GJ, et al. An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial. Ocul Surf. 2020;18(1):148-157. PubMed
  18. Saleh-Ghadimi S, Kheirouri S, Golmohammadi A, Moludi J, Jafari-Vayghan H, Alizadeh M. Effect of flaxseed oil supplementation on anthropometric and metabolic indices in patients with coronary artery disease: A double-blinded randomized controlled trial. J PubMed
  19. Jamilian M, Tabassi Z, Reiner Z, et al. The effects of n-3 fatty acids from flaxseed oil on genetic and metabolic profiles in patients with gestational diabetes mellitus: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2020;123(7):792-799
  20. Li L, Li H, Gao Y, Vafaei S, Zhang X, Yang M. Effect of flaxseed supplementation on blood pressure: a systematic review, and dose-response meta-analysis of randomized clinical trials. Food Funct 2023;14(2):675-690. PubMed
  21. Mahmudiono T, Jasim SA, Karim YS, et al. The effect of flaxseed oil consumption on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials. Phytother Res 2022;36(10):

See these in context on the Flaxseed Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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