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Dietary supplement

Organic Graviola Leaf Liquid Extract Ingredients & Drug Interactions

by Herbal Goodness

Organic Graviola Leaf Liquid Extract label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Graviola Leaf Liquid Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Graviola Leaf Liquid Extract is a dietary supplement by Herbal Goodness with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Graviola (Soursop) leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Graviola Leaf Liquid Extract by Herbal Goodness

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Graviola Leaf Liquid Extract by Herbal Goodness — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Graviola Leaf Liquid Extract by Herbal Goodness

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: organic Graviola (Soursop) leaf extract. The inactive ingredients are glycerin, organic Graviola, and purified water.

It's a liquid extract designed to deliver the herb in concentrated form.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Graviola's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: cell regeneration, stress relief, and restful sleep.
  • We looked for evidence on: Cough, Diabetes, Headache, sleep quality, relaxation, cellular health.
  • The closest evidence on file: Graviola is rated "Insufficient Reliable Evidence To Rate" for Headache (Natural Medicines).
  • Also on file: Graviola is rated "Insufficient Reliable Evidence To Rate" for Cough, Diabetes.

The evidence for graviola's effectiveness isn't established in the data we hold. The supplement is sometimes used for headache, HPV-related concerns, insect repellent, and male infertility, but we have insufficient reliable evidence to rate how well it works for any of these.

The evidence, ingredient by ingredient Graviola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Graviola raises some safety concerns you should know about. Regular use may not be safe — the most common side effects from oral use are stomach pain and nausea, and a small number of clinical trial participants reported nausea and burning pain in the upper stomach after taking 300 mg daily.

Rare but serious effects include movement disorders and nerve damage (myeloneuropathy) that can resemble Parkinson disease. One large study found that even low amounts of graviola fruit, juice, or herbal tea worsened motor and thinking symptoms in people with Parkinson disease.

Additionally, human safety data are limited overall, and lab studies raise concerns about possible nerve toxicity with long-term use. During pregnancy, the safety data advises against it — it's rated possibly unsafe.

During breastfeeding, there's no reliable safety information, so it's best avoided. Talk with your pharmacist or doctor about your individual situation.

Side effects, ingredient by ingredient Graviola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Graviola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Carbamazepine (Tegretol), a seizure medication, may have lower blood levels if you take graviola — this is a Moderate interaction. If you take this drug, check with your pharmacist or doctor before adding this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Graviola leaf extract is traditionally used for various conditions, but we don't have solid evidence it works for them, and it carries real safety concerns — especially movement problems and nerve damage with regular use. If you take carbamazepine for seizures, this product could interfere with it.

If you're pregnant, breastfeeding, or have any concern about neurological health, talk with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Graviola Leaf Liquid Extract, straight from the product label.

Brand Herbal Goodness
Barcode (UPC) 798304395136
Net contents 12 fl. Oz.; 354 mL
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261278
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Graviola Leaf Liquid Extract by Herbal Goodness, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
23
UPC/BARCODE
798304395136
IngredientAmount% DV
organic Graviola (Soursop) leaf extract1000 mg--

Other ingredients: Glycerin, organic Graviola, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Organic Graviola (also known as Soursop or Guanabana) leaf extract provides amazing health benefits and promotes healthy cell regeneration and rejuvenation. It supports stress relief by improving restful sleep and promoting calm relaxation.

Approved Keto Friendly

Certified Kosher by Earth Kosher

General Statements

100% Women Owned, 10% of Profits & Ethical trade Quality We Only Use the Best Made from the best quality herbs, our products are tested to the highest standard by 3rd party certifiers. Impact We Do Right By Others We believe in business for social good and give 10% of profits to support the education of African girls. Sustainability We Respect Mother Earth We believe in the environment and support our farmers through fairtrade practices..

100% Satisfaction Guaranteed Questions or comments? Instagram @herbalgoodnessco Twitter @herbal_goodness Visit herbalgoodnessco.com for a complete line of products

Formulation

Made with Non-GMO ingredients

USDA Organic

Cell Regeneration & Stress Relief

Certified Organic by Oregon Tilth

Seals/Symbols

Packaged in the USA

USDA Organic

EarthKosher

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 tablespoon, 2 to 3 times a day with food. May be diluted with water or juice.

Storage

Warning: Store tightly closed in a cool dry place.

Precautions

Do not use if inner seal or tamper evident seal is broken.

If pregnant or have a medical condition, consult your physician before using this herbal product.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Graviola Leaf Liquid Extract by Herbal Goodness label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Graviola Leaf Liquid Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Graviola Leaf Liquid Extract by Herbal Goodness

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container23 Amounts shown are per serving.

Organic Graviola (Soursop) leaf extract

Interacts with
1 drug
1000 mg per serving

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...

Organic Graviola (Soursop) leaf extract monograph & interactions

Other (inactive) ingredients: Glycerin, Organic Graviola, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Graviola Leaf Liquid Extract by Herbal Goodness Drug Interactions

Want to check YOUR meds against Organic Graviola Leaf Liquid Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

organic Graviola (Soursop) leaf extract 1

Individual Drug Interactions

The ingredients in Organic Graviola Leaf Liquid Extract interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Organic Graviola Leaf Liquid Extract interact with drugs. Each result below shows which ingredient is responsible. organic Graviola (Soursop) leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Graviola Leaf Liquid Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Graviola (Soursop) leaf extract1 drug type · 1 drug

Carbamazepine (Tegretol)

Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.

Likelihood Possible Evidence D
organic Graviola (Soursop) leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Graviola Leaf Liquid Extract, from the product label.

Herbal Goodness

See all Herbal Goodness products
Name
Herbal Goodness
Street Address
2150 S. Central Expressway Suite 200
City
McKinney
State
TX
ZipCode
75070
Phone Number
1-800-820-4829
Web Address
www.herbalgoodnessco.com
Pharmacist Counseling Corner

Organic Graviola Leaf Liquid Extract by Herbal Goodness: Common Questions

Does Organic Graviola Leaf Liquid Extract by Herbal Goodness interact with any medications?
Yes. Based on its ingredients, Organic Graviola Leaf Liquid Extract has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Graviola Leaf Liquid Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
During pregnancy, the safety data advises against it — it's rated possibly unsafe. During breastfeeding, there's no reliable safety information available, so it's also best avoided. Talk with your pharmacist or doctor about your individual situation before using it.
What are the side effects?
The most common side effects from regular oral use are stomach pain and nausea. Rare but serious effects include movement disorders and nerve damage (myeloneuropathy) that can resemble Parkinson disease. One study found that even small amounts of graviola worsened motor and thinking problems in people with Parkinson disease.
Does graviola actually work for headaches or HPV?
We have insufficient reliable evidence to rate how well it works for headaches, HPV concerns, or the other conditions it's traditionally used for. The evidence just isn't established in our data.
Why does the label say it may not be safe with long-term use?
Human safety data on graviola are limited, and lab studies raise concerns about possible nerve toxicity if you take it for a long time. That's why we recommend talking with your pharmacist before starting it, especially if you plan to use it regularly.
What's in this besides the graviola extract?
The inactive ingredients are glycerin, organic Graviola, and purified water. These are the liquid's base — the active part is the graviola leaf extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Graviola Leaf Liquid Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Graviola Leaf Liquid Extract label
Go deeper

The Full Monographs Behind Organic Graviola Leaf Liquid Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Graviola

Interacts with 1 drug

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Africa, and Asia. Despite popular online cla...

Read the full Graviola monograph →
Sources

Sources & How We Checked

Organic Graviola Leaf Liquid Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Graviola 4 references
  1. Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
  2. Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
  3. Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
  4. Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed

See these in context on the Graviola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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