Papaya Fruit Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Papaya Fruit Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Papaya Fruit Extract is a dietary supplement by Earthborn Elements with 1 active ingredient. Its ingredients are commonly taken for digestive upset and indigestion, constipation, wound and skin care (topical).Based on those ingredients, 92 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Papaya Fruit Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Papaya Fruit Extract by Earthborn Elements
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Papaya Fruit Extract by Earthborn Elements
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: papaya fruit extract in powder form, delivered in a capsule. Gelatin is listed as an inactive ingredient (the capsule material).
Does it work?
Couldn't assess
The evidence we hold doesn't establish that papaya fruit extract works for the conditions it's sometimes used for — aging skin, hair loss, colorectal cancer, or diabetes all show insufficient reliable evidence to rate. That doesn't mean it's ineffective, only that the data to support these uses isn't established in our resources.
How safe is it?
Well-documented data
Ripe papaya fruit is generally well tolerated when eaten as food. The concentrated supplement form and unripe (green) papaya are less well studied and carry more caution.
Nausea and vomiting have been reported with papaya leaf extract in studies. Allergic reactions are possible, especially in people allergic to latex, and can include itchy watery eyes, runny nose, sneezing, abdominal cramps, sweating, and diarrhea.
Regarding pregnancy and breastfeeding: the data shows ripe papaya is likely safe during pregnancy and lactation, but unripe papaya, papaya latex, and seeds should be avoided, particularly in pregnancy. Supplement amounts have little reliable safety information, so moderate ripe fruit is likely fine but concentrated supplements are best discussed with your doctor or pharmacist first.
Meds to double-check
Moderate interaction found
Before you take this product, check your medications if you're on blood thinners like warfarin, diabetes drugs, amiodarone, or levothyroxine. All four drug types interact with papaya extract at Moderate severity, meaning the product may change how your medications work or increase side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Papaya fruit extract comes with real medication interactions — especially with blood thinners, diabetes drugs, heart rhythm medications, and thyroid hormone. If you're on any prescription, check with your doctor or pharmacist before starting.
The evidence for its health claims isn't established in our data. Eating ripe papaya as food is different from taking a concentrated supplement, so talk it over with your own healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Papaya Fruit Extract, straight from the product label.
| Brand | Earthborn Elements |
|---|---|
| Net contents | 200 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 21, 2023 |
| DSLD ID | 283932 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Papaya Fruit Extract by Earthborn Elements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Papaya Fruit Extract, Powder | 400 mg | -- |
Other ingredients: Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule 1 to 3 times daily, preferably with meals, or as directed by a physician. Take with at least 8 oz of liquid.
Precautions
If you are pregnant, nursing, or taking medication, consult your healthcare professional before taking this or any dietary supplement.
For adults only.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease or health condition.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Papaya Fruit Extract by Earthborn Elements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Papaya Fruit Extract by Earthborn Elements
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.
Papaya Fruit Extract, Powder
Interacts with92 drugs
Papaya is a tropical fruit that is nutritious and generally safe to eat as food, and it contains an enzyme called papain used as a digestive aid and m...
Papaya Fruit Extract, Powder monograph & interactionsOther (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.
Papaya Fruit Extract by Earthborn Elements Drug Interactions
HelloPharmacist Interaction Report
Papaya Fruit Extract by Earthborn Elements has documented interactions with several medication types.
The most serious concern is with blood thinners (anticoagulants) like warfarin — papaya extract containing papain may increase warfarin's effects and side effects, raising bleeding risk. In one case, a patient stable on warfarin developed dangerously high levels after taking a papaya supplement.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check before combining this with diabetes medications, amiodarone (a heart rhythm drug), or levothyroxine (thyroid hormone). With diabetes drugs, fermented papaya preparations have shown additive blood-sugar-lowering effects in a small study, though it's unclear if other papaya forms do the same.
Amiodarone levels may rise and become more potent. Levothyroxine's effects may decrease — one patient eating 5–6 papaya fruits daily for two weeks became underactive after years of stable hormone therapy.
Altogether, these interactions span 92 individual medications. Before you start this product, run your exact prescriptions through the search tool below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Papaya Fruit Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Papaya Fruit Extract interact with 92 drugs. Click any drug to see the details.
1 of the 1 ingredient in Papaya Fruit Extract interact with drugs. Each result below shows which ingredient is responsible. Papaya Fruit Extract, Powder
GlucagonBaqsimi, Glucagon
How Glucagon interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Glucagon interactionGlucoseIV Glucose
How Glucose interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Glucose interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Glyburide interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Glyburide, Metformin interactionInhaled InsulinExubera
How Inhaled Insulin interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Inhaled Insulin interactionInsulinNovoRapid Insulin
How Insulin interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin interactionInsulin (bovine)Hypurin Bovine Neutral
How Insulin (bovine) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin (bovine) interactionInsulin (human)Afrezza, Novolin 70/30, Novolin L, Novolin N, Novolin R
How Insulin (human) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin (human) interactionInsulin (pork)Hypurin Porcine Neutral, Lente Iletin II, NPH Iletin, NPH Iletin II, Pork Actrapid, Regular Iletin +1 more
How Insulin (pork) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin (pork) interactionInsulin (rdna)Actrapid, Humalog, Humalog Mix 75/25, Humulin 50/50, Humulin 70/30, Humulin L +8 more
How Insulin (rdna) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin (rdna) interactionInsulin AspartFiasp
How Insulin Aspart interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Aspart interactionInsulin Aspart, Insulin DegludecRyzodeg 70/30
How Insulin Aspart, Insulin Degludec interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Aspart, Insulin Degludec interactionInsulin DegludecTresiba
How Insulin Degludec interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Degludec interactionInsulin Degludec, LiraglutideXultophy 100/3.6
How Insulin Degludec, Liraglutide interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Degludec, Liraglutide interactionInsulin GlargineBasaglar, Lusduna, Semglee
How Insulin Glargine interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Glargine interactionInsulin Glargine (rdna)Lantus
How Insulin Glargine (rdna) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Glargine (rdna) interactionInsulin Glargine RecombinantToujeo Solostar
How Insulin Glargine Recombinant interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Glargine Recombinant interactionInsulin Glargine, LixisenatideSoliqua 100/33
How Insulin Glargine, Lixisenatide interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Glargine, Lixisenatide interactionInsulin Glulisine (rdna)Apidra
How Insulin Glulisine (rdna) interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Glulisine (rdna) interactionInsulin Human, Sodium ChlorideMyxredlin
How Insulin Human, Sodium Chloride interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Human, Sodium Chloride interactionInsulin LisproAdmelog, Admelog Solostar
How Insulin Lispro interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Lispro interactionInsulin Lispro RecombinantHumalog Kwikpen
How Insulin Lispro Recombinant interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Lispro Recombinant interactionInsulin Lispro-aabcLyumjev
How Insulin Lispro-aabc interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Lispro-aabc interactionInsulin DetermirLevemir
How Insulin Determir interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Insulin Determir interactionLevothyroxineEltroxin, Estre, Euthyrox, Levo-T, Levolet, Levothroid +5 more
How Levothyroxine interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Theoretically, consuming large quantities of papaya fruit can reduce the clinical effects of levothyroxine.
Read the full Papaya Fruit Extract, Powder + Levothyroxine interactionLevothyroxine SodiumErmez, Thyquidity, Tirosint-Sol
How Levothyroxine Sodium interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Theoretically, consuming large quantities of papaya fruit can reduce the clinical effects of levothyroxine.
Read the full Papaya Fruit Extract, Powder + Levothyroxine Sodium interactionLevothyroxine, LiothyronineArmour Thyroid
How Levothyroxine, Liothyronine interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Theoretically, consuming large quantities of papaya fruit can reduce the clinical effects of levothyroxine.
Read the full Papaya Fruit Extract, Powder + Levothyroxine, Liothyronine interactionLinagliptinTradjenta
How Linagliptin interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Linagliptin interactionLinagliptin, Metformin HydrochlorideJentadueto XR
How Linagliptin, Metformin Hydrochloride interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Linagliptin, Metformin Hydrochloride interactionLiraglutideVictoza
How Liraglutide interacts with Papaya Fruit Extract — through 1 ingredient. Tap an ingredient for the detail:
Papaya Fruit Extract, PowderAntidiabetes Drugs Moderate
Interaction Summary
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects.
Read the full Papaya Fruit Extract, Powder + Liraglutide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Papaya Fruit Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Papaya Fruit Extract, Powder
Amiodarone (Cordarone)
Theoretically, papaya extract may increase the levels and clinical effects of amiodarone.
Animal research in rats shows that a single oral dose of papaya extract, as well as multiple doses of papaya extract daily over 14 days, prior to a single dose of amiodarone delays the time to maximum amiodarone concentration. However, only the 14-day papaya extract regimen increases systemic amiodarone exposure by 60% to 70%. This interaction has not been reported in humans.
Antidiabetes Drugs
Concomitant use of antidiabetic drugs with fermented papaya can produce additive effects. It is unclear if other forms of papaya have the same effect.
A small low-quality clinical study in patients with type 2 diabetes who are taking glibenclamide shows that taking a fermented papaya preparation 3 grams daily for 2 months decreases fasting and postprandial blood glucose levels when compared to baseline. Additionally, of the 25 patients in the study, 9 required a reduction in glibenclamide dose.
Levothyroxine (Synthroid, Others)
Theoretically, consuming large quantities of papaya fruit can reduce the clinical effects of levothyroxine.
In one case-report, a 37-year-old male with a history of thyroidectomy who was stabilized on levothyroxine for 5 years presented with hypothyroidism after consuming 5-6 papaya fruits daily for 14 days during vacation. In a controlled re-challenge test involving 5-6 papayas daily, the patient remained euthyroid for 7 days, but developed mild hypothyroidism after 14 days. Both times, thyroid levels normalized 40-45 days after discontinuing papaya.
Warfarin (Coumadin)
Theoretically, concomitant use of warfarin with papain-containing papaya extract might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.
Brand information
Manufacturer and brand details for Papaya Fruit Extract, from the product label.
Earthborn Elements
See all Earthborn Elements products- Name
- Earthborn Elements
- Street Address
- 9450 SW Gemini Dr., #49936
- City
- Beaverton
- State
- OR
- ZipCode
- 97008
- Web Address
- Earthbornelements.com
Papaya Fruit Extract by Earthborn Elements: Common Questions
Does Papaya Fruit Extract by Earthborn Elements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this papaya extract safe during pregnancy?
What side effects might I have from taking this?
Does papaya extract actually work for diabetes?
Is this safe to take long-term?
What exactly is papaya fruit extract?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Papaya Fruit Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Papaya Fruit Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Papaya Fruit Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Papaya 14 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
- Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
- Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
- Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
- Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
- Oderinde, O., Noronha, C., Oremosu, A., Kusemiju, T., and Okanlawon, O. A. Abortifacient properties of aqueous extract of Carica papaya (Linn) seeds on female Sprague-Dawley rats. Niger.Postgrad.Med J 2002;9(2):95-98. DOI
- Danese, C., Esposito, D., D'Alfonso, V., Cirene, M., Ambrosino, M., and Colotto, M. Plasma glucose level decreases as collateral effect of fermented papaya preparation use. Clin Ter. 2006;157(3):195-198.
- Iliev, D. and Elsner, P. Generalized drug reaction due to papaya juice in throat lozenges. Dermatology 1997;194(4):364-366. PubMed
- Andersen HA, Bernatz PE, Grindlay JH. Perforation of the esophagus after use of a digestant agent: report of case and experimental study. Ann Otol Rhinol Laryngol 1959;68:890-6. PubMed
- Deiana L, Marini S, Mariotti S. Ingestion of large amounts of papaya fruit and impaired effectiveness of levothyroxine therapy. Endocr Pract 2012;18(1):98-100. PubMed
- Rodrigues M, Alves G, Francisco J, Fortuna A, Falcão A. Herb-drug pharmacokinetic interaction between Carica papaya extract and amiodarone in rats. J Pharm Pharm Sci 2014;17(3):302-15. PubMed
- Rajapakse S, de Silva NL, Weeratunga P, Rodrigo C, Sigera C, Fernando SD. Carica papaya extract in dengue: a systematic review and meta-analysis. BMC Complement Altern Med. 2019;19(1):265. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC