PEA Ingredients & Drug Interactions
What is this page for?
First and foremost: checking PEA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
PEA is a dietary supplement by X Gold Health with 2 active ingredients. Its ingredients are commonly taken for chronic pain, nerve (neuropathic) pain, inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of PEA by X Gold Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
X Gold Health PEA contains two active ingredients. Palmitoylethanolamide (PEA) is a naturally occurring fatty acid compound your body produces, thought to help manage inflammation.
Luteolin is a plant compound, though we don't have detailed information on file about its role in this formula. The product also contains cellulose, an inactive ingredient used as a filler.
Does it work?
Not established
The evidence for PEA is mixed. It's rated possibly effective for osteoarthritis, meaning some studies show benefit but the evidence isn't rock-solid yet.
For migraine headache, carpal tunnel syndrome, autism spectrum disorder, and cannabis use disorder, we don't have enough reliable evidence to say whether it works. PEA was rated possibly ineffective for spinal cord injury.
We don't have effectiveness data on file for luteolin in this product.
How safe is it?
Well-documented data
Palmitoylethanolamide is generally well tolerated in studies, though long-term safety data are limited. The most common side effect reported is nausea.
Very rarely, it may cause mild, short-lived digestive symptoms. If you apply a PEA lotion, a small number of people experienced itching, stinging, scaling, or redness, but these didn't happen more often than with the base lotion alone.
There isn't enough safety information about PEA during pregnancy or breastfeeding, so the safety data advises against use in both. Talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing and considering this product.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check in X Gold Health PEA. We don't hold interaction information for luteolin, so if you're taking medications, it's still worth a quick review with your pharmacist to be thorough.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
X Gold Health PEA might be worth considering if you're dealing with osteoarthritis and want to explore a supplement with limited but promising early evidence. If you're pregnant, breastfeeding, or nursing, avoid it—the safety data aren't there.
If you take any regular medications, check them against this product first, and talk with your pharmacist if you have questions about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about PEA, straight from the product label.
| Brand | X Gold Health |
|---|---|
| Net contents | 120 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 317159 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for PEA by X Gold Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Palmitoylethanolamide | 630 mg | -- |
| Luteolin | 30 mg | -- |
Other ingredients: Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports healthy inflammatory responses Natural pain management support
Micronized for higher bioavailability
Zero gluten, soy, eggs, dairy, nuts, preservatives or animal products
Manufactured and quality tested in the USA Ingredients carefully sourced from around the world
Non GMO ingredients Verified
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement take two (2) capsules once or twice a day with food and a full glass of water. Best when taken as directed by a qualified healthcare professional.
Precautions
Keep out of the reach of children.
No recommended for pregnant or lactating women.
Storage
Store tightly closed in a dry place at controlled room temperature of 50 degrees - 86 degrees F.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Your health is Gold! Be happy!
Formula
Pea Palmitoylethanolamide + Luteolin
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Third Party Tested GMP Good Manufactured Practice Premium Quality Quality Control Approved Non GMO Ingredients Verified Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
PEA by X Gold Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in PEA by X Gold Health
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Palmitoylethanolamide
No knowninteractions
Palmitoylethanolamide (PEA) is a fat-like molecule made naturally in the body and studied mainly for pain and inflammation. Some research suggests it...
Palmitoylethanolamide monograph & interactionsLuteolin
Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.
PEA by X Gold Health Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in PEA. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for PEA, from the product label.
X Gold Health
See all X Gold Health products- Name
- X Gold Health LLC
- City
- Miami
- State
- FL
- ZipCode
- 33141
- Web Address
- www.xgoldhealth.com
PEA by X Gold Health: Common Questions
Does PEA by X Gold Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is PEA, and why is it in this product?
Can I take this if I'm pregnant or breastfeeding?
Does this product really work for arthritis?
What side effects might I experience?
Is this safe to take with my medications?
What's cellulose doing in here?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if PEA is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind PEA’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
PEA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Palmitoylethanolamide (pea) 4 references
- Indraccolo U, Barbieri F. Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. Eur J Obstet Gynecol Reprod Biol. 2010 May;150(1):76-9. PubMed
- Murina F, Graziottin A, Felice R, Radici G, Tognocchi C. Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation. J Low Genit Tract Dis. 2013 Apr;17(2):111-6.
- Papetti L, Sforza G, Tullo G, et al. Tolerability of palmitoylethanolamide in a pediatric population suffering from migraine: A pilot study. Pain Res Manag 2020;2020:3938640. PubMed
- Visse K, Blome C, Phan NQ, Augustin M, Ständer S. Efficacy of body lotion containing N-palmitoylethanolamine in subjects with chronic pruritus due to dry skin: A dermatocosmetic study. Acta Derm Venereol. 2017;97(5):639-641. PubMed
See these in context on the Palmitoylethanolamide (pea) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC