Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Alpha GPC + Uridine Ingredients & Drug Interactions

by X Gold Health

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Alpha GPC + Uridine is a dietary supplement by X Gold Health with 2 active ingredients. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Alpha-Glycerylphosphorylcholine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Alpha GPC + Uridine by X Gold Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients: alpha-GPC and uridine 5'-monophosphate disodium salt. Alpha-GPC is a compound that delivers choline to your brain and is studied for memory and cognitive support.

Uridine is a nucleoside that plays a role in cell energy and nerve health. The capsules also contain cellulose and silica as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports brain function memory focus and cognitive health.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Mental clarity, Age-related cognitive decline, Learning.
  • The strongest evidence on file: Alpha-gpc is rated "Possibly Effective" for Alzheimer disease (Natural Medicines).
  • Also on file: Alpha-gpc is rated "Insufficient Reliable Evidence To Rate" for Cognitive function.

Alpha-GPC is possibly effective for Alzheimer disease. For brain tumors, cognitive function, vascular dementia, and stroke, the evidence isn't strong enough to rate it either way.

We don't hold effectiveness data for uridine in this product.

The evidence, ingredient by ingredient Alpha-gpc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated in studies, though long-term safety hasn't been fully established. Rarely, people taking it by mouth have reported dizziness, headache, insomnia, and nausea.

There's also a rare signal of elevated stroke risk in people who've used alpha-GPC for at least 2 months compared with non-users or shorter-term users — talk with your doctor or pharmacist before starting if stroke risk concerns you. We don't have pregnancy or lactation safety data on file for either ingredient, so check with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Alpha-gpc

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check scopolamine (Transderm Scop) before you start — alpha-GPC may reduce its effects. We could not check uridine 5'-monophosphate disodium salt against medications, so ask your pharmacist about it too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Alpha GPC + Uridine may be worth considering if you're looking at cognitive support, especially for Alzheimer disease where alpha-GPC has some evidence. If you take scopolamine (motion sickness patch) or any other medications, check them with your pharmacist first.

The long-term safety story isn't complete, so this is a conversation starter, not a no-brainer.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha GPC + Uridine, straight from the product label.

Brand X Gold Health
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 310936
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha GPC + Uridine by X Gold Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Alpha-Glycerylphosphorylcholine600 mg--
Uridine 5'-Monophosphate Disodium Salt300 mg--

Other ingredients: Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports formation of brain synapses Neuronal membranes Potent nootropic

Supports brain function Mental acuity Cognitive support Memory Supports brain health Focus Energy

Zero gluten, soy, eggs, dairy, nuts, preservatives or animal products Ingredients non GMO verified

Vegan Friendly

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) vegetarian capsules daily, preferably with a meal or as directed by your healthcare professional.

Precautions

Keep out of reach of children.

Not recommended for pregnant or lactating women.

Storage

Store tightly closed in a dry place at controlled room temperature of 50 Degrees - 86 Degrees F.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Manufactured at FDA Inspected Facility GMP Good Manufactured Practice Third Party Tested Ingredients Non GMO Verified Made in USA Vegan Friendly

General Statements

Your health is gold! Be happy!

See for yourself

Alpha GPC + Uridine by X Gold Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Alpha GPC + Uridine by X Gold Health

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alpha-Glycerylphosphorylcholine

Interacts with
16 drugs
600 mg per serving Form: L-Alpha-Glycerylphosphorylcholine

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha-Glycerylphosphorylcholine monograph & interactions

Uridine 5'-Monophosphate Disodium Salt

300 mg per serving

Other (inactive) ingredients: Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha GPC + Uridine by X Gold Health Drug Interactions

Want to check YOUR meds against Alpha GPC + Uridine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha GPC + Uridine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha-Glycerylphosphorylcholine1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Alpha GPC + Uridine, from the product label.

X Gold Health

See all X Gold Health products
Name
X Gold Health LLC
City
Miami
State
FL
ZipCode
33141
Web Address
www.xgoldhealth.com
Pharmacist Counseling Corner

Alpha GPC + Uridine by X Gold Health: Common Questions

Does Alpha GPC + Uridine by X Gold Health interact with any medications?
Yes. Based on its ingredients, Alpha GPC + Uridine has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha GPC + Uridine contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does alpha-GPC actually work for memory and thinking?
Alpha-GPC is possibly effective for Alzheimer disease based on the evidence we hold. For other cognitive issues like general brain function or stroke recovery, we don't have enough reliable evidence to say one way or the other. Your doctor can help you weigh whether it's right for your situation.
Can I take this if I use a scopolamine patch for motion sickness?
You should talk to your doctor or pharmacist before combining them. Alpha-GPC might weaken the patch's effect — a small study showed it can partially counteract scopolamine's impact on attention and memory. Whether that translates to less motion sickness relief isn't completely clear, so get personalized advice before starting.
What side effects should I watch for?
Most people tolerate alpha-GPC well, but rarely, people have reported dizziness, headache, insomnia, and nausea. There's also a rare signal of higher stroke risk in people using it for 2 months or longer compared with non-users, so mention that to your doctor if you have stroke risk factors.
Is this safe if I'm pregnant or breastfeeding?
We don't have safety data on file for either ingredient during pregnancy or breastfeeding. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.
What's in this product besides the active ingredients?
The capsules contain cellulose and silica as inactive ingredients — those are just the capsule material and a flow agent.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Alpha GPC + Uridine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha GPC + Uridine label
Go deeper

The Full Monographs Behind Alpha GPC + Uridine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Alpha GPC + Uridine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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