Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

High G Hardcare Formulation Muscle Booster Ingredients & Drug Interactions

by High T

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

High G Hardcare Formulation Muscle Booster is a dietary supplement by High T with 3 active ingredients. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are SerinAid, AlphaSize. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of High G Hardcare Formulation Muscle Booster by High T

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “AlphaSize” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.
  • “SerinAid” is listed as a grouped ingredient — the label gives one combined amount (200 mg) without saying how much of each component you get.

High G contains three active ingredients: phosphatidylserine, alpha-GPC (L-alpha-glyceryl phosphoryl choline), and an amino acid blend. Phosphatidylserine is a fatty compound thought to support cell membrane function and brain health.

Alpha-GPC is a choline derivative believed to support cognitive function and brain signaling. The amino acid blend's exact composition isn't detailed on file.

The product is filled with standard capsule ingredients — gelatin capsule, cellulose, dicalcium phosphate, magnesium stearate, silica, and color additives (titanium dioxide and FD&C dyes).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: assist the body in its output of muscle.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Muscle strength, Muscle growth, Resistance training recovery.
  • The closest evidence on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness.

For phosphatidylserine, there's possibly effective evidence for age-related cognitive decline and Alzheimer's disease. For athletic performance, cognitive function generally, ADHD, and dementia, the evidence isn't reliable enough to rate.

For alpha-GPC, there's possibly effective evidence for Alzheimer's disease. For brain tumors, cognitive function, vascular dementia, and stroke, the evidence isn't reliable enough to rate.

We don't have effectiveness data on file for the amino acid blend.

The evidence, ingredient by ingredient Alpha-gpc Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both phosphatidylserine and alpha-GPC are generally well tolerated in studies, though long-term safety isn't fully established. Common side effects from phosphatidylserine include flatulence, stomach upset, headache, insomnia (especially at higher doses like 600 mg), and nausea — these can occur at doses of 200–300 mg daily.

Alpha-GPC rarely causes dizziness, headache, insomnia, diarrhea, heartburn, nausea, and vomiting. Rarely, it's been linked to stroke, particularly with use lasting 2 months or longer compared to non-users.

There isn't enough safety data during pregnancy or breastfeeding for either phosphatidylserine or alpha-GPC — talk with your doctor or pharmacist about whether this product is right for you in those situations.

Side effects, ingredient by ingredient Alpha-gpc Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Phosphatidylserine, Alpha-gpc.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on anticholinergic drugs (drugs for overactive bladder, Parkinson's, or related conditions) or cholinergic drugs — phosphatidylserine may affect their effectiveness. Also check if you use a scopolamine patch (Transderm Scop) for motion sickness, as alpha-GPC might reduce its effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

High G is aimed at muscle and athletic support, but the evidence for phosphatidylserine and alpha-GPC in athletic performance isn't strong. If you take anticholinergic or cholinergic medications, or use a scopolamine motion-sickness patch, check with your doctor or pharmacist before starting — this product may interfere with how they work.

Pregnant or breastfeeding? The safety data isn't there yet; talk it over with your own provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High G Hardcare Formulation Muscle Booster, straight from the product label.

Brand High T
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2013
DSLD ID 18508
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High G Hardcare Formulation Muscle Booster by High T, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
8 Capsule(s)
Servings per container
30
IngredientAmount% DV
Phosphatidylserine100 mg--
AlphaSize300 mg--
SerinAid200 mg--
L-Alpha-Glyceryl Phosphoryl Choline150 mg--
Amino Acid Blend650 mg--

Other ingredients: Gelatin, Cellulose, Di Calcium Phosphate, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, FD&C Blue #1, FD&C Red #40, FD&C Yellow #6, FD&C Yellow #5

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

High G(TM) is scientifically formulated to assist the body in its output of muscle.

WORK HARD, PLAY HARD, RECOVER FASTER(TM)

Alphasize(R) and SerinAid(R) are trademarks of Chemi Nutra, Inc. Sustamine(TM) is a trademark of Kyowa Hakko Bio Co., Ltd. High T(R) is a registered trademark of KingFisher Media, LLC.

High G(TM) is the bench of athletes watching your back.

Now the High T(R) brand introduces High G(TM), specially formulated and designed to meet your need to get bigger.**

The scientifically formulated combination in High G(TM) is now available to help you meet your driven outcome to get bigger.

Seals/Symbols

MADE IN USA GOOD MANUFACTURING PRACTICE MANUFACTURED IN A GMP CERTIFIED FACILITY QUALITY GUARANTEED kingfisher media

SerinAid(R) PhosphatidylSerine AlphaSize(R) Alpha-Glyceryl Phosphoryl Choline

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

USAGE: Take one (1) serving (4) capsules daily. Workout day: Take two (2) servings - (8) capsules 90 minutes prior to resistance exercise.

Precautions

(Do not exceed 8 capsules daily). PRECAUTIONS: Use only as directed.

Do not take this product if you are pregnant or nursing.

Consult a health care professional before use if you are allergic to any ingredients, have a serious medical condition, or use prescription medications.

For adult use only.

General Statements

Scientifically Formulated Natural Muscle Production** Natural Strength Gain** Energy with Ultimate Endurance** **In association with weight training.

ULTIMATEMUSCLE

Reduce recovery time, increase your capacity and work to be the biggest player in the game. Dedication is your best friend.

Give yourself the edge. You earn it with every lift** ULTIMATE MUSCLE IS YOUR FRIEND.

You know the drill. Building muscle requires stacking of many things; nutrition, training, dedication and trusted outcome from the right supplements.

ULTIMATE MUSCLE The effort of building muscle mass is continuously tested by dedicated body builders.

FDA Statement of Identity

DIETARY SUPPLEMENT

See for yourself

High G Hardcare Formulation Muscle Booster by High T label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High G Hardcare Formulation Muscle Booster by High T

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

AlphaSize

Interacts with
16 drugs
300 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

AlphaSize monograph & interactions

SerinAid

Interacts with
219 drugs
200 mg per serving

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

SerinAid monograph & interactions

Amino Acid Blend

650 mg per serving Form: Arginine Alpha-Ketoglutarate, L-Arginine, L-Citrulline, L-Glutamine, L-Isoleucine, L-Leucine, Sustamine(TM) L-Alanyl-L-Glutamine

Other (inactive) ingredients: Gelatin, Cellulose, Di Calcium Phosphate, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, FD&C Blue #1, FD&C Red #40, FD&C Yellow #6, FD&C Yellow #5. These complete the product’s ingredient list but are not active constituents.

Interaction report

High G Hardcare Formulation Muscle Booster by High T Drug Interactions

Want to check YOUR meds against High G Hardcare Formulation Muscle Booster?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

SerinAid 219

Each ingredient & the kinds of drugs it affects

For each ingredient in High G Hardcare Formulation Muscle Booster with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

SerinAid2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B

AlphaSize1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for High G Hardcare Formulation Muscle Booster, from the product label.

High T

See all High T products
Name
KingFisher Media, LLC
Phone Number
1-877-902-7743
Web Address
www.HighTProducts.com
Pharmacist Counseling Corner

High G Hardcare Formulation Muscle Booster by High T: Common Questions

Does High G Hardcare Formulation Muscle Booster by High T interact with any medications?
Yes. Based on its ingredients, High G Hardcare Formulation Muscle Booster has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
High G Hardcare Formulation Muscle Booster contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What causes the side effects I've read about — headache, upset stomach, insomnia?
Those come from phosphatidylserine. Flatulence, nausea, and stomach upset can happen at doses around 200–300 mg daily. Headache and insomnia occur too, and insomnia is more likely when you take a higher dose like 600 mg. Most people tolerate it fine, but these are worth knowing if they happen to you.
Is this safe if I'm pregnant or breastfeeding?
There isn't enough safety information for either phosphatidylserine or alpha-GPC during pregnancy or lactation. The safety data advises against use unless your doctor directs otherwise. Talk with your doctor or pharmacist to decide what's right for your situation.
What's alpha-GPC and what's it supposed to do?
Alpha-GPC is a choline compound believed to support brain function and cognitive health. It's possibly effective for Alzheimer's disease, but the evidence for athletic performance or general cognitive boost isn't reliable enough to rate yet.
I've read that alpha-GPC can cause stroke — is that real?
In rare cases, alpha-GPC has been linked to stroke when used for 2 months or longer, compared to people who didn't use it or used it for less time. It's an uncommon side effect, but it's something to be aware of and to mention to your doctor if you're considering long-term use.
Does this product really boost athletic performance?
The evidence for phosphatidylserine and alpha-GPC in athletic performance isn't strong enough to rate reliably right now. That's what the data we hold shows — so talk with your doctor about whether it's the right choice for your fitness goals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High G Hardcare Formulation Muscle Booster is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High G Hardcare Formulation Muscle Booster label
Sources

Sources & How We Checked

High G Hardcare Formulation Muscle Booster's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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