Phosphatidyl Serine 300 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Phosphatidyl Serine 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidyl Serine 300 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Phosphatidyl Serine 300 mg by Double Wood Supplements
Ask about any prescription or over-the-counter medication and we check it for interactions with Phosphatidyl Serine 300 mg by Double Wood Supplements — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Phosphatidyl Serine 300 mg by Double Wood Supplements
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: phosphatidylserine 300 mg per capsule. Phosphatidylserine is a naturally occurring compound in cell membranes thought to support brain health.
The capsule itself is made from gelatin, and the filling includes microcrystalline cellulose as a binder.
Does it work?
Moderate evidence
Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease based on the evidence we have. For athletic performance, attention deficit-hyperactivity disorder (ADHD), general cognitive function, and dementia, the evidence is currently insufficient to rate its effectiveness.
The data we hold doesn't establish how well it may work for those uses.
How safe is it?
Well-documented data
Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully established. Common side effects include flatulence, gastrointestinal upset, headache, insomnia, and nausea.
Gastrointestinal upset can occur at doses of 200–300 mg per day; insomnia is more likely at higher doses like 600 mg. There isn't enough safety information to recommend this product during pregnancy, so avoidance is advised.
Safety while breastfeeding is unknown—talk with your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Before you take this product, have your doctor or pharmacist review any anticholinergic medications you're on—phosphatidylserine might make them less effective. Also flag any cholinergic drugs, since this supplement could add to their effects.
These are Moderate-severity concerns, so a quick check is worth it.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Phosphatidyl Serine might help with age-related memory loss or Alzheimer disease, though the evidence is moderate. If you take anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting—this supplement could interfere with how those drugs work.
Pregnancy and breastfeeding require a conversation with your healthcare provider before use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidyl Serine 300 mg, straight from the product label.
| Brand | Double Wood Supplements |
|---|---|
| Barcode (UPC) | X001PGA2I9 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 241931 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidyl Serine 300 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Phosphatidylserine | 300 mg | -- |
Other ingredients: Gelatin, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Phosphatidylserine is an amino acid compound that is found in high concentrations in the brain. Research suggests Phosphatidylserine supports mental processing speed and accuracy, cognitive function and supports memory when taken as a supplement.
PhosphatidylSerine DoubleWood Supplements New
Suggested/Recommended/Usage/Directions
Suggested Use: Take two (2) capsules per day.
Storage
Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.
Precautions
Warning: Consult your physician before use if you are taking any medications, are pregnant, nursing, or are under 18 years of age.
Do not consume more than 900mg (6 capsules) per day.
Discontinue use and consult your doctor immediately if any adverse reactions occur.
Do not take Phosphatidylserine and operate heavy machinery until you know how it affects you.
Warning: Consult your physician before use if you are taking any medications, are pregnant, nursing, or are under 18 years of age. Keep out of reach of children.
Allergen: Contains soy
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Supports mental processing speed and cognitive acuity Supports memory
Proudly made in USA
Made with Non-GMO ingredients Gluten Free
Formula
300 mg per serving
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidyl Serine 300 mg by Double Wood Supplements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidyl Serine 300 mg by Double Wood Supplements
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Phosphatidylserine
Interacts with219 drugs
Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...
Phosphatidylserine monograph & interactionsOther (inactive) ingredients: Gelatin, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Phosphatidyl Serine 300 mg by Double Wood Supplements Drug Interactions
HelloPharmacist Interaction Report
Phosphatidyl Serine 300 mg by Double Wood Supplements interacts with anticholinergic and cholinergic drugs through its active ingredient phosphatidylserine.
The most serious documented interaction is Moderate severity: phosphatidylserine may reduce how well anticholinergic medications work. It's thought to raise acetylcholine levels in your body, which could interfere with drugs designed to lower acetylcholine activity.
Read the full breakdown — every affected drug type, severity by severity
The product also carries a Moderate interaction with cholinergic drugs—medications that increase acetylcholine. Taking phosphatidylserine alongside these could theoretically add to their effects, potentially causing too much cholinergic activity.
Altogether, these interactions span 219 individual medications. Before you start this supplement, check your exact prescriptions against the tool on this page, especially if you take any anticholinergic or cholinergic medication.
Your doctor or pharmacist can tell you whether the combination is safe for you.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Phosphatidyl Serine 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Phosphatidyl Serine 300 mg interact with 219 drugs. Click any drug to see the details.
1 of the 1 ingredient in Phosphatidyl Serine 300 mg interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine
AmifampridineRuzurgi
How Amifampridine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Phosphatidylserine + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Phosphatidylserine + Amifampridine Phosphate interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aminoglutethimide interactionAmitriptylineElavil
How Amitriptyline interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline, Perphenazine interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAtropineSal-Tropine
How Atropine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine interactionAtropine Methyl Nitrate, Digestive EnzymesFestalan
How Atropine Methyl Nitrate, Digestive Enzymes interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine Methyl Nitrate, Digestive Enzymes interactionAtropine SulfateAtropine Sulfate, Isopto Atropine
How Atropine Sulfate interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine Sulfate interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, PhenylAtrosept
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl SalicylateUrinary Antiseptic 2, Urised
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, DifenoxinMotofen
How Atropine, Difenoxin interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Difenoxin interactionAtropine, DiphenoxylateLofene, Lomotil
How Atropine, Diphenoxylate interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Diphenoxylate interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, ScopolamineColytrol
How Atropine, Hyoscyamine, Scopolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Morphine Sulfate interactionBarbital, Hyoscyamine, Scopolamine, Passiflora, ValeriBarbatose #2
How Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interactionBelladonna Alkaloids (prescription Drug)Bellafoline
How Belladonna Alkaloids (prescription Drug) interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids (prescription Drug) interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna Alkaloids, PhenobarbitalBarbidonna, Donnatal
How Belladonna Alkaloids, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Phenobarbital interactionBelladonna Extract, Butabarbital SodiumButibel
How Belladonna Extract, Butabarbital Sodium interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Extract, Butabarbital Sodium interactionBelladonna Extract, PhenobarbitalBelap
How Belladonna Extract, Phenobarbital interacts with Phosphatidyl Serine 300 mg — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Phosphatidyl Serine 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Phosphatidylserine
Anticholinergic Drugs
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.
Cholinergic Drugs
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.
Brand information
Manufacturer and brand details for Phosphatidyl Serine 300 mg, from the product label.
Double Wood Supplements
See all Double Wood Supplements products- Name
- Double Wood LLC
- Street Address
- 3510 Scotts Ln Ste 219
- City
- Philadelphia
- State
- PA
- ZipCode
- 19129-1573
- Web Address
- www.doublewoodsupplements.com
Phosphatidyl Serine 300 mg by Double Wood Supplements: Common Questions
Does Phosphatidyl Serine 300 mg by Double Wood Supplements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What side effects might I notice?
Does phosphatidylserine actually work for memory?
What is phosphatidylserine and what does it do?
Are there any fillers or junk in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidyl Serine 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidyl Serine 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Phosphatidyl Serine 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylserine 9 references
- Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
- Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
- Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
- Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
- Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
- Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
- Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
- Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
- Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC