Phyto-Gen Intest-gen Ingredients & Drug Interactions
by Genestra Brands
What is this page for?
First and foremost: checking Phyto-Gen Intest-gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phyto-Gen Intest-gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for memory and concentration, digestive upset, hair growth.Based on those ingredients, 372 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rosemary (Rosmarinus officinalis) young shoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Phyto-Gen Intest-gen by Genestra Brands
Ask about any prescription or over-the-counter medication and we check it for interactions with Phyto-Gen Intest-gen by Genestra Brands — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Phyto-Gen Intest-gen by Genestra Brands
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Phyto-Gen Intest-gen contains three active plant extracts. Rosemary young shoot extract is included for its traditional use; English walnut bud extract is present for digestive support; and lingonberry young shoot extract rounds out the formula.
The product is delivered in liquid form and also contains purified water, ethanol, and glycerin as inactive ingredients (carriers and preservatives).
Does it work?
Moderate evidence
The evidence on these ingredients is mixed and limited. Rosemary extract is possibly effective for memory support, though it is not established for age-related cognitive decline, alopecia areata, or fatty liver disease.
English walnut bud extract is possibly effective for high cholesterol but lacks reliable evidence for heart disease or diabetes. Lingonberry extract has insufficient evidence to support its use for dental plaque or urinary tract infections.
Overall, the data we hold does not establish this combination's effectiveness for any specific condition.
How safe is it?
Well-documented data
Rosemary extract is safe in normal food amounts, but concentrated extracts require caution. Orally, it can cause allergic reactions, occupational asthma in sensitive people, and the undiluted oil may trigger seizures; topically, allergic contact dermatitis and photosensitivity have occurred.
English walnut can cause serious allergic reactions in people with tree nut allergies, and the concentrated extracts in this product have not been well studied. Lingonberry is generally well tolerated but may cause nausea and vomiting due to its tannin content.
During pregnancy, rosemary extract is possibly unsafe at medicinal doses, English walnut has conflicting safety data, and lingonberry is rated likely unsafe — talk with your doctor or pharmacist before use if you are pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
Before taking Phyto-Gen Ingest-gen, check with your doctor or pharmacist if you take anticoagulant or antiplatelet drugs (blood thinners) — moderate risk of increased bleeding. Also confirm if you use antidiabetes drugs, aspirin, or other salicylate-containing pain relievers like choline magnesium trisalicylate or salsalate, as rosemary may have additive effects.
If you take medications broken down by the liver enzyme CYP1A2, rosemary may reduce their effectiveness, though this effect has not been seen in humans. When in doubt, bring your medication list to your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed for digestive support from plant extracts, but the scientific evidence for effectiveness is not established in our data. If you take blood thinners, diabetes medications, aspirin, or other salicylate-containing pain relievers, you'll need to check with your doctor or pharmacist before starting it — rosemary carries documented moderate interaction risks with these drug types.
If you have tree nut allergies, steer clear. Discuss this product with your own healthcare provider, especially if you're pregnant, breastfeeding, or on any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phyto-Gen Intest-gen, straight from the product label.
| Brand | Genestra Brands |
|---|---|
| Barcode (UPC) | 883196117116 |
| Net contents | 0.5 fl. Oz.; 15 mL |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 230959 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phyto-Gen Intest-gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rosemary (Rosmarinus officinalis) young shoot extract | 0.09 mL | -- |
| English Walnut (Juglans regia) bud extract | 0.09 mL | -- |
| Lingonberry (Vaccinium vitis-idaea) young shoot extract | 0.09 mL | -- |
Other ingredients: purified Water, Ethanol, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.
General Statements
For warnings and additional information, see outer box.
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Scan to learn about our quality excellence
Precautions
Keep out of the reach of children.
Use only if safety seal is intact.
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
This product was sealed for your protection. Do not use if box or contents are open or damaged.
Storage
Store in a cool, dry place.
FDA Statement of Identity
Dietary Supplement
Formula
English Walnut Rosemary Lingonberry
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phyto-Gen Intest-gen by Genestra Brands label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phyto-Gen Intest-gen by Genestra Brands
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Rosemary (Rosmarinus officinalis) young shoot extract
Interacts with372 drugs
Rosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory...
Rosemary (Rosmarinus officinalis) young shoot extract monograph & interactionsEnglish Walnut (Juglans regia) bud extract
No knowninteractions
English walnut is a nutritious tree nut rich in plant-based omega-3 fats, fiber, and antioxidants, and eating it as part of a balanced diet may suppor...
English Walnut (Juglans regia) bud extract monograph & interactionsLingonberry (Vaccinium vitis-idaea) young shoot extract
No knowninteractions
Lingonberry is a tart red berry rich in antioxidants such as anthocyanins and the compound arbutin, and it is popular as a food and folk remedy for ur...
Lingonberry (Vaccinium vitis-idaea) young shoot extract monograph & interactionsOther (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.
Phyto-Gen Intest-gen by Genestra Brands Drug Interactions
HelloPharmacist Interaction Report
Phyto-Gen Intest-gen by Genestra Brands contains rosemary extract, which interacts with several medication types.
The most serious concern is a moderate risk of increased bleeding if you take anticoagulant or antiplatelet drugs (blood thinners) — rosemary may inhibit platelet aggregation and compound their effect.
Read the full breakdown — every affected drug type, severity by severity
Rosemary also carries moderate interaction risks with antidiabetes drugs (a theoretical increased risk of low blood sugar), aspirin, and other salicylate-containing pain relievers like choline magnesium trisalicylate and salsalate, since rosemary itself contains salicylates. There is also a minor risk that rosemary may decrease the effectiveness of certain medications metabolized by the liver enzyme CYP1A2, though this has not been confirmed in humans.
English walnut bud extract and lingonberry young shoot extract, the other two active ingredients, have no documented interactions in our data. Altogether, these interactions span 372 individual medications.
Before you start this product, run your exact medications through the interaction checker below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Phyto-Gen Intest-gen?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Phyto-Gen Intest-gen interact with 372 drugs. Click any drug to see the details.
1 of the 3 ingredients in Phyto-Gen Intest-gen interact with drugs. Each result below shows which ingredient is responsible. Rosemary (Rosmarinus officinalis) young shoot extract
AbciximabReoPro
How Abciximab interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Phyto-Gen Intest-gen — through 1 ingredient. Tap an ingredient for the detail:
Rosemary (rosmarinus Officinalis) Young Shoot ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary (rosmarinus Officinalis) Young Shoot Extract + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Phyto-Gen Intest-gen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rosemary (Rosmarinus officinalis) young shoot extract
Anticoagulant/Antiplatelet Drugs
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.
Aspirin
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.
Choline Magnesium Trisalicylate (Trilisate)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.
Salsalate (Disalcid)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Phyto-Gen Intest-gen, from the product label.
Genestra Brands
- Name
- Seroyal USA
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15275
- Phone Number
- 1-888-737-6925
- Web Address
- seroyal.com
Phyto-Gen Intest-gen by Genestra Brands: Common Questions
Does Phyto-Gen Intest-gen by Genestra Brands interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Does this product contain any major allergens?
What is rosemary extract actually used for in this product?
Is this a concentrated supplement or a food-strength product?
Could this product cause loose stools or stomach upset?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phyto-Gen Intest-gen is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phyto-Gen Intest-gen’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Rosemary
Interacts with 372 drugsRosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory, mood, and hair growth, but the evidenc...
Read the full Rosemary monograph → Herb & supplement monographEnglish Walnut
English walnut is a nutritious tree nut rich in plant-based omega-3 fats, fiber, and antioxidants, and eating it as part of a balanced diet may support heart health. Most concentrated supple...
Read the full English Walnut monograph → Herb & supplement monographLingonberry
Lingonberry is a tart red berry rich in antioxidants such as anthocyanins and the compound arbutin, and it is popular as a food and folk remedy for urinary tract and general wellness. Human...
Read the full Lingonberry monograph →Sources & How We Checked
Phyto-Gen Intest-gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rosemary 20 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Swain AR, Dutton SP, Truswell AS. Salicylates in foods. J Am Diet.Assoc 1985;85(8):950-60. DOI
- Zhu BT, Loder DP, Cai MX, et al. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis 1998;19(10):1821-7. PubMed
- Debersac P, Heydel JM, Amiot MJ, et al. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol 2001;39(9):907-18. PubMed
- Debersac P, Vernevaut MF, Amiot MJ, et al. Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver. Food Chem Toxicol 2001;39(2):109-17. PubMed
- Lee JJ, Jin YR, Lee JH, et al. Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis. Planta Med 2007;73(2):121-7.
- Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
- Naemura A, Ura M, Yamashita T, et al. Long-term intake of rosemary and common thyme herbs inhibits experimental thrombosis without prolongation of bleeding time. Thromb Res 2008;122(4):517-22. PubMed
- Lee JJ, Jin YR, Lim Y, et al. Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. Vascul Pharmacol 2006;45:148-53. PubMed
- Bakirel, T., Bakirel, U., Keles, O. U., Ulgen, S. G., and Yardibi, H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J Ethnopharmacol 2-28-2008;116(1):64-73. PubMed
- Erenmemisoglu, A., Saraymen, R., and Ustun, S. Effect of a Rosmarinus officinalis leave extract on plasma glucose levels in normoglycaemic and diabetic mice. Pharmazie 1997;52(8):645-646.
- Valones MAA, Silva ICG, Gueiros LAM, Leão JC, Caldas AF Jr, Carvalho AAT. Clinical assessment of rosemary-based toothpaste (Rosmarinus officinalis Linn.): A randomized controlled double-blind study. Braz Dent J. 2019;30(2):146-151. PubMed
- Quirarte-Báez SM, Zamora-Perez AL, Reyes-Estrada CA, et al. A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD). J Popul Ther Clin Pharmacol. 2019;26(4):e18-e28.
- Al Jamal A. Effect of rosemary (Rosmarinus officinalis) on lipid profiles and blood glucose in human diabetic patients (type-2). African J. Biochem. Res. 2014;8(8):147-50. DOI
English Walnut 16 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Zambon D, Sabate J, Munoz S, et al. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann Intern Med 2000;132:538-46. PubMed
- Chisholm A, Mann J, Skeaff M, et al. A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur J Clin Nutr 1998;52:12-6. PubMed
- Sabate J, Fraser GE, Burke K, et al. Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med 1993;328:603-7. PubMed
- Feldman EB. The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J Nutr 2002;132:1062S-101S. PubMed
- Asero R. Detection and clinical characterization of patients with oral allergy syndrome caused by stable allergens in Rosaceae and nuts. Ann Allergy Asthma Immunol 1999;83:377-83. PubMed
- Bonamonte D, Foti C, Angelini G. Hyperpigmentation and contact dermatitis due to Juglans regia. Contact Dermatitis 2001;44:101-2. PubMed
- Hu FB, Stampfer MJ. Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence. Curr Atheroscler Rep 1999;1:204-9. PubMed
- Tapsell LC, Gillen LJ, Patch CS, et al. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care 2004;27:2777-83. PubMed
- Rabiei K, Ebrahimzadeh MA, Saeedi M, et al. Effects of a hydroalcoholic extract of Juglans regia (walnut) leaves on blood glucose and major cardiovascular risk factors in type 2 diabetic patients: a double-blind, placebo-controlled clinical trial. BMC Com PubMed
- Hosseini S, Jamshidi L, Mehrzadi S, et al. Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: a randomized double-blind, placebo-controlled clinical trial. J Ethnopharmacol. 2014;152(3):451-6. PubMed
- FDA. Qualified Health Claims: Letter of Enforcement Discretion - Walnuts and Coronary Heart Disease (Docket No 02P-0292). March 2004. Available at: http://wayback.archive-it.org/7993/20171114183649/https:/www.fda.gov/Food/IngredientsPackagingLabeling/Labe
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
- Mirzababaei A, Daneshvar M, Abaj F, et al. The Effect of Walnut (Juglans regia) Leaf Extract on Glycemic Control and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Clin Nutr Re
Lingonberry 4 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Kontiokari T, Sundqvist K, Nuutinen M, et al. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ 2001;322:1571.
- Ferrara, P., Romaniello, L., Vitelli, O., Gatto, A., Serva, M., and Cataldi, L. Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand.J Urol.Nephrol. 2009;43(5):369-372. PubMed
- Pärnnen P, Nikula-Ijs P, Sorsa T. Antimicrobial and Anti-inflammatory Lingonberry Mouthwash - A Clinical Pilot Study in the Oral Cavity. Microorganisms. 2019;7(9):331. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC