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Dietary supplement

Phyto-Gen White Birch Bud Ingredients & Drug Interactions

by Genestra Brands

Phyto-Gen White Birch Bud label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Phyto-Gen White Birch Bud against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Phyto-Gen White Birch Bud is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for urinary tract and 'flushing' support, joint pain and arthritis, mild fluid retention (diuretic).Based on those ingredients, 75 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are White Birch (Betula pubescens) bud extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Phyto-Gen White Birch Bud by Genestra Brands

Ask about any prescription or over-the-counter medication and we check it for interactions with Phyto-Gen White Birch Bud by Genestra Brands — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Phyto-Gen White Birch Bud by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Phyto-Gen White Birch Bud contains one active ingredient: white birch (Betula pubescens) bud extract, a traditional botanical extract commonly used in herbal formulations. The liquid form also includes inactive ingredients — purified water, ethanol (grain alcohol), and glycerin — which help preserve and deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Birch product and its label doesn't state a use — see Birch's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for white birch bud extract is not yet established. The data we hold shows insufficient reliable evidence to rate it for joint pain, hair loss (alopecia), or dandruff — the conditions it's traditionally associated with.

That doesn't mean it doesn't work, only that clinical studies haven't confirmed it reliably enough for us to vouch for it.

The evidence, ingredient by ingredient Birch

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

White birch bud extract is generally well tolerated in food-like amounts, though allergy concerns and quality variability warrant caution. Birch and birch pollen can trigger allergic reactions in sensitive people, ranging from mild to contact dermatitis (skin inflammation) when applied topically.

A case of allergic contact dermatitis was reported in someone using a birch bark cream — betulin, a compound in birch, was suspected as the culprit. Crushed birch leaves and fresh birch sap may also cause this skin reaction.

The safety data advises against using birch supplements during pregnancy or while breastfeeding, so those are times to skip it. If you have a known birch pollen allergy or sensitivity, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Birch

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Birch.
  • The most serious interaction on file is rated Minor.
  • For scale: 75 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take diuretic medications (water pills), check with your doctor or pharmacist before using this product — birch may theoretically interfere with how well they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Phyto-Gen White Birch Bud is a single-ingredient botanical with a history in traditional use, but clinical evidence for joint pain, hair loss, or dandruff isn't solid yet. If you take diuretics, are pregnant, breastfeeding, or have a birch pollen allergy, discuss this product with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phyto-Gen White Birch Bud, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196128105
Net contents 0.5 fl. Oz.; 15 mL
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230974
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phyto-Gen White Birch Bud by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
883196128105
IngredientAmount% DV
White Birch (Betula pubescens) bud extract0.28 mL--

Other ingredients: purified Water, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Use only if safety seal is intact.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our quality excellence

For warnings and additional information, see outer box.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Phyto-Gen White Birch Bud by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Phyto-Gen White Birch Bud label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Phyto-Gen White Birch Bud by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

White Birch (Betula pubescens) bud extract

Interacts with
75 drugs
0.28 mL per serving

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid...

White Birch (Betula pubescens) bud extract monograph & interactions

Other (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phyto-Gen White Birch Bud by Genestra Brands Drug Interactions

Want to check YOUR meds against Phyto-Gen White Birch Bud?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
75Drugs
75 Minor

Ingredients driving the most interactions

White Birch (Betula pubescens) bud extract 75

Individual Drug Interactions

The ingredients in Phyto-Gen White Birch Bud interact with 75 drugs. Click any drug to see the details.

1 of the 1 ingredient in Phyto-Gen White Birch Bud interact with drugs. Each result below shows which ingredient is responsible. White Birch (Betula pubescens) bud extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Phyto-Gen White Birch Bud with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Birch (Betula pubescens) bud extract1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D
White Birch (Betula pubescens) bud extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Phyto-Gen White Birch Bud, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Phyto-Gen White Birch Bud by Genestra Brands: Common Questions

Does Phyto-Gen White Birch Bud by Genestra Brands interact with any medications?
Yes. Based on its ingredients, Phyto-Gen White Birch Bud has a known interaction with 75 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phyto-Gen White Birch Bud contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have a birch pollen allergy?
Birch extract can trigger allergic reactions in people sensitive to birch pollen, so you shouldn't take it without talking to your doctor or pharmacist first. They can help you weigh the risk based on how severe your allergy is.
Is this safe during pregnancy?
No — the safety data advises against using birch supplements in pregnancy. If you're pregnant or planning to be, talk with your doctor or pharmacist before taking this.
Can I use this while breastfeeding?
No — safety hasn't been established while breastfeeding, so it's best to avoid it. Ask your doctor or pharmacist if you have questions about alternatives.
Does this actually work for joint pain or hair loss?
The clinical evidence isn't strong enough yet to confirm it. The data shows insufficient reliable evidence to rate white birch bud extract for those uses, so we can't say whether it works.
What's in the liquid besides the birch extract?
The liquid contains purified water, ethanol (grain alcohol), and glycerin as inactive ingredients — they help preserve and deliver the extract.
Can I get a rash from this?
Yes — birch can cause allergic contact dermatitis (a skin reaction) in some people, especially when applied topically. Crushed birch leaves and fresh birch sap have also been linked to this reaction, so skin contact is a concern if you're sensitive.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phyto-Gen White Birch Bud is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phyto-Gen White Birch Bud label
Go deeper

The Full Monographs Behind Phyto-Gen White Birch Bud’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Birch

Interacts with 75 drugs

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...

Read the full Birch monograph →
Sources

Sources & How We Checked

Phyto-Gen White Birch Bud's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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