Postnatal Fenugreek 2,000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Postnatal Fenugreek 2,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Postnatal Fenugreek 2,000 mg is a dietary supplement by Nature's Truth with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Postnatal Fenugreek 2,000 mg by Nature's Truth
Ask about any prescription or over-the-counter medication and we check it for interactions with Postnatal Fenugreek 2,000 mg by Nature's Truth — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Postnatal Fenugreek 2,000 mg by Nature's Truth
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: fenugreek seed extract at 2,000 mg per dose. Fenugreek is a plant seed used traditionally to support milk supply and sexual function.
The capsule also contains inactive ingredients — rice powder, gelatin, magnesium stearate, and silica — which are fillers and binders.
Does it work?
Not established
Fenugreek is rated possibly effective for sexual dysfunction and sexual arousal, as well as for dysmenorrhea (menstrual cramps) and type 2 diabetes. That means some clinical evidence supports its use for these purposes, but the research isn't yet definitive.
If you're considering it for any of these reasons, talk with your pharmacist or doctor about what the current evidence shows for your specific situation.
How safe is it?
Well-documented data
Fenugreek seed is generally well tolerated in food amounts, but supplement doses can cause side effects. The most common are abdominal pain, bloating, diarrhea, indigestion, gas, low blood sugar (hypoglycemia), and nausea.
Rare but serious allergic reactions — including swelling of the throat and mouth (angioedema), severe breathing problems (bronchospasm), and shock — have been reported. One quirk: if you take fenugreek during pregnancy or while nursing, it may give a newborn an unusual body odor that could be mistaken for maple syrup urine disease, though this appears to go away on its own.
The supplement amounts in this product may affect the uterus, so avoid medicinal use during pregnancy. While fenugreek is often used to boost milk supply, the evidence is limited — talk with your doctor or lactation consultant first if you're breastfeeding.
Meds to double-check
Moderate interaction found
Before taking this supplement, check with your pharmacist if you're on any of these: blood thinners or antiplatelet drugs like warfarin or clopidogrel (moderate risk of increased bleeding), diabetes medications (moderate risk of low blood sugar), blood pressure medications like metoprolol (moderate risk of blood pressure dropping too low), theophylline, phenytoin, or sildenafil (moderate risk that the drug won't work as well). Use the search tool on this page to check your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Postnatal Fenugreek may be worth considering if you're looking to support milk supply or address sexual function or dysmenorrhea, though the evidence is strongest for sexual function. If you take any blood thinners, diabetes medications, blood pressure drugs, seizure medications, or theophylline, you need to check with your pharmacist first — fenugreek can interact with all of these.
Avoid this product if you're pregnant.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Postnatal Fenugreek 2,000 mg, straight from the product label.
| Brand | Nature's Truth |
|---|---|
| Barcode (UPC) | 840093101907 |
| Net contents | 100 Quick Release Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 306791 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Women (not pregnant or lactating), Adult Female (18 - 50 Years), Lactating, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Postnatal Fenugreek 2,000 mg by Nature's Truth, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek | 2000 mg | -- |
| Fenugreek Seed Extract | 200 mg | -- |
Other ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
100% quality Satisfaction guarantee Certified Authentic Tru-ID DNA Tested
DNA Tested Botanicals
Our non-GMO pledge Visit our website
Formulation
Gluten free Non GMO
Popular with lactating women
Certified authentic Tru-ID
No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO
General Statements
Vitamins
Formula
Postnatal Fenugreek 2,000 mg per serving Equivalent from 200 mg of 10:1 extract per serving.
Herbal Support for Nursing Mothers
Fenugreek is an annual herb native to western Asia and southern Europe that has long been used in culinary applications and as an herbal tonic. The seeds of this plant contain a rich supply of naturally-occurring phytonutrients and saponins.
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take two (2) quick release capsules daily, preferably with a meal.
Precautions
Warning: Not for use during pregnancy or if you are attempting to become pregnant. If you are nursing, taking any medications or have any medical condition, consult your doctor before use.
If any adverse reactions occur, immediately stop using this product and consult your doctor.
Not intended for use by persons under the age of 18.
If seal under cap is damaged or missing, do not use.
Keep out of reach of children.
Storage
Store in a cool, dry place.
Brand IP Statement(s)
Copyright 2022 Nature's Truth LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Postnatal Fenugreek 2,000 mg by Nature's Truth label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Postnatal Fenugreek 2,000 mg by Nature's Truth
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Quick Release Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.
Fenugreek
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek monograph & interactionsOther (inactive) ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Postnatal Fenugreek 2,000 mg by Nature's Truth Drug Interactions
HelloPharmacist Interaction Report
Nature's Truth Postnatal Fenugreek 2,000 mg contains fenugreek seed extract, which has documented interactions with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (anticoagulants/antiplatelets): fenugreek may add to their effects, raising the risk of bleeding. This includes warfarin and clopidogrel specifically, where case reports and animal data suggest fenugreek can increase bleeding risk or alter how the drug works.
Read the full breakdown — every affected drug type, severity by severity
Fenugreek also interacts with diabetes medications — it can lower blood sugar on its own, so combining it with antidiabetes drugs may cause blood sugar to drop too far. You'll also want to flag blood pressure medications like metoprolol; fenugreek may lower blood pressure further.
Three other drug types interact as well: theophylline (a breathing medication), phenytoin (a seizure medication), and sildenafil — fenugreek may reduce how well these work by speeding up how your body clears them.
Altogether, these interactions span 386 individual medications. Please use the search tool on this page to check any prescription or over-the-counter drugs you take before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Postnatal Fenugreek 2,000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Postnatal Fenugreek 2,000 mg interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Postnatal Fenugreek 2,000 mg interact with drugs. Each result below shows which ingredient is responsible. Fenugreek
AbciximabReoPro
How Abciximab interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Postnatal Fenugreek 2,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Postnatal Fenugreek 2,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Postnatal Fenugreek 2,000 mg, from the product label.
Nature's Truth
See all Nature's Truth products- Name
- Nature's Truth LLC
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-844-544-1030
- Web Address
- NaturesTruth.com
Postnatal Fenugreek 2,000 mg by Nature's Truth: Common Questions
Does Postnatal Fenugreek 2,000 mg by Nature's Truth interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does fenugreek actually help with milk supply?
What are the most common side effects?
Can I take this while pregnant?
Will this help with sexual function?
Is this safe to take with my diabetes or blood pressure medication?
What's in the capsule besides the active ingredient?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Postnatal Fenugreek 2,000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Postnatal Fenugreek 2,000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Postnatal Fenugreek 2,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
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