Power Mushrooms Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Power Mushrooms against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Power Mushrooms is a dietary supplement by Health Concerns with 4 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 771 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Poria Sclerotium Extract, Reishi Fruiting Body Extract, Maitake fruiting body extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Power Mushrooms by Health Concerns
Ask about any prescription or over-the-counter medication and we check it for interactions with Power Mushrooms by Health Concerns — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Power Mushrooms by Health Concerns
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Power Mushrooms contains four active ingredients: a proprietary herbal blend, reishi fruiting body extract, maitake fruiting body extract, and poria sclerotium extract. The maitake and poria are concentrated extracts from the fruiting bodies of the mushrooms themselves.
The product also contains two inactive ingredients — hypromellose (a capsule material) and rice bran — as excipients. All four active ingredients are from medicinal mushroom sources, traditional in Chinese herbalism.
Beyond the blend's listed components, we don't have specifics on what else is included or its concentration.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that any of these ingredients work for their intended purpose. Maitake mushroom has been studied for hay fever, chemotherapy-related anemia, laryngeal cancer, diarrhea, and chronic fatigue syndrome, but the data isn't strong enough to rate it.
Poria mushroom has been studied for similar conditions — cancer, chronic fatigue, dementia, diabetes, and diabetic kidney disease — again without reliable evidence to support it. We have no effectiveness data on file for reishi or tremella fruiting body extracts.
How safe is it?
Well-documented data
Maitake and poria mushroom extracts are both generally well tolerated as whole foods, though supplement safety hasn't been fully studied for either. Maitake's most common side effects are gastrointestinal: in clinical trials, a small number of participants reported diarrhea, nausea, and stomach pain.
One person had a rash and itching after two doses, though it cleared on its own. Poria is rarely associated with allergic reactions like allergic rhinitis or allergic asthma.
Pregnancy and breastfeeding: the safety data for maitake and poria concentrated supplements during pregnancy and lactation is not enough to know either way. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or breastfeeding.
We have no pregnancy or breastfeeding data on file for reishi or tremella.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you take warfarin (Coumadin) or any other blood thinner — maitake mushroom can increase their effects and raise bleeding risk. Also flag blood pressure medications, diabetes drugs (including insulin), sedatives, and any drugs for urinary or neurological conditions.
These are the main medication types we have documented interactions for.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Power Mushrooms is a medicinal mushroom blend that carries documented moderate interactions with blood thinners, blood pressure drugs, and diabetes medications — mainly through its maitake and poria components. If you take warfarin, a blood pressure medication, insulin, or any diabetes drug, this product needs a conversation with your pharmacist first.
The evidence for what these mushrooms actually do isn't established in the data we hold.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Power Mushrooms, straight from the product label.
| Brand | Health Concerns |
|---|---|
| Barcode (UPC) | 810034440990 |
| Net contents | 270 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 259434 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Power Mushrooms by Health Concerns, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Herbal Blend | 650 mg | -- |
| Reishi Fruiting Body Extract | 0 NP | -- |
| Maitake fruiting body extract | 0 NP | -- |
| Poria Sclerotium Extract | 0 NP | -- |
| Tremella Fruiting Body Extract | 0 NP | -- |
Other ingredients: Hypromellose, Rice Bran
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Chinese Traditional Formulas
Suggested/Recommended/Usage/Directions
Suggested Use: One capsule, 3 times per day between meals, or as recommended by your health care practitioner.
Precautions
Notice: As with any dietary supplement, do not take without first consulting your health care practitioner, especially if you are pregnant, nursing, or are under medical supervision for any reason.
Notice: As with any dietary supplement, do not take without first consulting your health care practitioner, especially if you are pregnant, nursing, or are under medical supervision for any reason.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Made in the U.S.A.
Formula
Ganoderma (Reishi)
FDA Statement of Identity
Herbal Supplement
Brand IP Statement(s)
Health Concerns Combining Modern Research and Ancient Wisdom
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Power Mushrooms by Health Concerns label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Power Mushrooms by Health Concerns
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container270 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Herbal Blend
- › Reishi Fruiting Body Extract
- › Maitake fruiting body extract
- › Poria Sclerotium Extract
- › Tremella Fruiting Body Extract
Other (inactive) ingredients: Hypromellose, Rice Bran. These complete the product’s ingredient list but are not active constituents.
Power Mushrooms by Health Concerns Drug Interactions
HelloPharmacist Interaction Report
Power Mushrooms by Health Concerns contains two ingredients we could check for interactions — maitake and poria mushroom extracts — and two we couldn't, so this picture is incomplete.
The most serious finding is maitake mushroom's moderate-severity interaction with warfarin (Coumadin), a blood thinner. A case report documented one patient whose warfarin levels climbed dangerously high after taking maitake mushroom extract; the patient's INR (a measure of blood thinning) jumped to 5.1 after just one week.
Read the full breakdown — every affected drug type, severity by severity
Maitake also carries moderate interactions with blood pressure medications and diabetes drugs. Theoretically, it may boost the effects of both, raising the risk of low blood pressure (hypotension) or low blood sugar (hypoglycemia).
Poria mushroom extract has three moderate interactions: it may enhance sedatives, theoretically reduce the effects of anticholinergic drugs (used for certain urinary or digestive symptoms), or add to the effects of cholinergic drugs (used in some neurological conditions). None of these poria interactions have been confirmed in humans — they're animal findings so far.
We couldn't check reishi fruiting body extract or tremella fruiting body extract because we hold no interaction data for them. Altogether, these interactions span 672 individual medications.
Before you start this product, run your exact medications through the checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Power Mushrooms?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Power Mushrooms interact with 771 drugs. Click any drug to see the details.
3 of the 4 ingredients in Power Mushrooms interact with drugs. Each result below shows which ingredient is responsible. Poria Sclerotium Extract Reishi Fruiting Body Extract Maitake fruiting body extract
AbciximabReoPro
How Abciximab interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruiting Body Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruiting Body Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Power Mushrooms — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruiting Body Extract + Acarbose interactionMaitake Fruiting Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Maitake Fruiting Body Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Power Mushrooms — through 2 ingredients. Tap an ingredient for the detail:
Maitake Fruiting Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Maitake Fruiting Body Extract + Acebutolol interactionReishi Fruiting Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Fruiting Body Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruiting Body Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruiting Body Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruiting Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruiting Body Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Power Mushrooms — through 1 ingredient. Tap an ingredient for the detail:
Poria Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium Extract + Acetaminophen, Chlorzoxazone, Codeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Power Mushrooms with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Poria Sclerotium Extract
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Reishi Fruiting Body Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Maitake fruiting body extract
Antidiabetes Drugs
Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.
Antihypertensive Drugs
Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.
Warfarin (Coumadin)
There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.
Brand information
Manufacturer and brand details for Power Mushrooms, from the product label.
Health Concerns
See all Health Concerns products- Name
- Health Concerns
- City
- Springville
- State
- Utah
- Phone Number
- 1 (800) 233-9355
- Web Address
- www.healthconcerns.com/pro
Power Mushrooms by Health Concerns: Common Questions
Does Power Mushrooms by Health Concerns interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are these mushroom extracts supposed to do?
Can I take this if I'm on a blood thinner like warfarin?
Is it safe during pregnancy?
What side effects should I watch for?
Why can't you check all the ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Power Mushrooms is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Power Mushrooms’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Reishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph → Herb & supplement monographMaitake Mushroom
Interacts with 260 drugsMaitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...
Read the full Maitake Mushroom monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph →Sources & How We Checked
Power Mushrooms's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
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Maitake Mushroom 8 references
- Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
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Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
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