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Dietary supplement

Premium Antarctic Krill Blend Ingredients & Drug Interactions

by Whole Body Research

Premium Antarctic Krill Blend label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Premium Antarctic Krill Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Premium Antarctic Krill Blend is a dietary supplement by Whole Body Research with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Premium Krill Oil Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Premium Antarctic Krill Blend by Whole Body Research

Ask about any prescription or over-the-counter medication and we check it for interactions with Premium Antarctic Krill Blend by Whole Body Research — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Premium Antarctic Krill Blend by Whole Body Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.
  • “Phospholipids” is listed as a grouped ingredient — the label gives one combined amount (420 mg) without saying how much of each component you get.
  • “Premium Krill Oil Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This three-ingredient softgel delivers omega-3 fatty acids from Antarctic krill oil — specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) — plus esterified astaxanthin, a carotenoid pigment from the krill itself. The krill oil base also supplies phospholipids, natural compounds that help your body absorb and use the omega-3s.

The capsule itself is gelatin, glycerin, and sorbitol, with purified water and fish oil as additional inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Brain health and heart health.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Cardiovascular disease (CVD), Hyperlipidemia, Hypertriglyceridemia, Heart failure — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Heart failure, Hyperlipidemia, Hypertension, and more.

Our data hold insufficient reliable evidence to rate astaxanthin for any of its commonly claimed uses — age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome all lack enough solid research. We don't hold effectiveness ratings for the krill oil's omega-3 content against this product's claims.

The evidence, ingredient by ingredient Krill Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are mild: abdominal pain, diarrhea, and red-colored stools.

At higher doses (40 mg daily, far above typical supplements), severe stomach pain has been reported in isolated cases. There isn't enough safety data to recommend this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist about whether it's right for you in those situations.

We hold no safety information for the krill oil's omega-3 components themselves.

Side effects, ingredient by ingredient Krill Oil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this supplement, check with your doctor or pharmacist if you take any medications metabolized by CYP3A4 or CYP2B6 enzymes — astaxanthin may lower their blood levels. These include many common drugs across multiple categories, so running your prescription list through the checker on this page is the best first step.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking for omega-3s from a marine source and you're not pregnant, breastfeeding, or taking medications broken down by CYP3A4 or CYP2B6 enzymes, this product is generally well tolerated. Because astaxanthin may lower blood levels of those drugs, check your exact medications with your doctor or pharmacist before starting — they can tell you whether any of yours are affected.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Premium Antarctic Krill Blend, straight from the product label.

Brand Whole Body Research
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 24, 2017
DSLD ID 70412
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Premium Antarctic Krill Blend by Whole Body Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
IngredientAmount% DV
Calories7 Calorie(s)--
Calories from Fat7 Calorie(s)1%
Eicosapentaenoic Acid150 mg--
Docosahexaenoic Acid90 mg--
Total Omega-3 Fatty Acids300 mg--
Esterified Astaxanthin1.5 mg--
Phospholipids420 mg--
Premium Krill Oil Blend1000 mg--

Other ingredients: Antarctic Krill Oil, Gelatin, Glycerin, Fish Oil, Haematococcus pluvialis, Astaxanthin Oleo, Sorbitol Solution, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 2 softgels daily, preferably with a meal.

General Statements

Premium Antarctic Krill Blend is made from the highest quality ingredients according to cGMP guidelines.

Brain health Heart health

Precautions

Warning: Consult your physician before using this product if you are allergic to shellfish or fish, suffer from a blood clotting disorder, use blood thinners or other medications or anticipate surgery.

Warning: Consult your physician before using this product if you are allergic to shellfish or fish, suffer from a blood clotting disorder, use blood thinners or other medications or anticipate surgery.

Warning: Consult your physician before using this product if you are allergic to shellfish or fish, suffer from a blood clotting disorder, use blood thinners or other medications or anticipate surgery.

Allergen Warning: Contains Shellfish(Krill) and Fish.

Storage

Store in a cool, dry place. Avoid excessive heat.

Seals/Symbols

Good manufacturing practice product GMP

Made in USA

FDA Disclaimer Statement

These statements have not been evaluated by The Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

Allergen Warning: Contains Shellfish(Krill) and Fish.

General

WBRKRILL-LBL-R3

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Premium Antarctic Krill Blend by Whole Body Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Premium Antarctic Krill Blend label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Premium Antarctic Krill Blend by Whole Body Research

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Premium Krill Oil Blend

Interacts with
208 drugs
1000 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Premium Krill Oil Blend monograph & interactions
  • › Phospholipids

Other (inactive) ingredients: Antarctic Krill Oil, Gelatin, Glycerin, Fish Oil, Haematococcus pluvialis, Astaxanthin Oleo, Sorbitol Solution, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Premium Antarctic Krill Blend by Whole Body Research Drug Interactions

Want to check YOUR meds against Premium Antarctic Krill Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Premium Krill Oil Blend 208

Individual Drug Interactions

The ingredients in Premium Antarctic Krill Blend interact with 838 drugs. Click any drug to see the details.

1 of the 1 ingredient in Premium Antarctic Krill Blend interact with drugs. Each result below shows which ingredient is responsible. Premium Krill Oil Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Premium Antarctic Krill Blend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Premium Krill Oil Blend2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Premium Krill Oil Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Premium Antarctic Krill Blend, from the product label.

Whole Body Research

See all Whole Body Research products
Name
Whole Body Research
City
Chatsworth
State
CA
ZipCode
91311
Phone Number
1-800-240-7721
Web Address
wholebodyresearch.com
Pharmacist Counseling Corner

Premium Antarctic Krill Blend by Whole Body Research: Common Questions

Does Premium Antarctic Krill Blend by Whole Body Research interact with any medications?
Yes. Based on its ingredients, Premium Antarctic Krill Blend has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Premium Antarctic Krill Blend contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the red color in my stool after taking this?
That's likely astaxanthin, the natural pigment in the krill — it's harmless and expected. A few people in studies saw it at doses as low as 6 mg daily, and it's one of the most common side effects reported.
Can I take this if I'm pregnant?
There isn't enough safety data yet. Talk with your doctor or pharmacist — they can help you decide based on your individual situation.
Can I take this while breastfeeding?
There isn't enough safety data yet. Check with your doctor or pharmacist for personalized advice before starting.
What does astaxanthin do in this product?
Our data don't have strong evidence for what it does for your health. It's a carotenoid from the krill itself and is generally well tolerated, but we don't have reliable research supporting it for the conditions it's often marketed for.
What if I get stomach pain from this?
Mild abdominal pain is one of the most commonly reported side effects and is usually manageable. Severe pain has been rare and was only seen at very high doses in a couple of cases. If it's bothersome or severe, stop and talk with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Premium Antarctic Krill Blend is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Premium Antarctic Krill Blend label
Go deeper

The Full Monographs Behind Premium Antarctic Krill Blend’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph →
Sources

Sources & How We Checked

Premium Antarctic Krill Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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