Premium Gold Energy Manuka Honey Blend Ingredients & Drug Interactions
by ManukaGuard
What is this page for?
First and foremost: checking Premium Gold Energy Manuka Honey Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Premium Gold Energy Manuka Honey Blend is a dietary supplement by ManukaGuard with 2 active ingredients. Its ingredients are commonly taken for cough and sore throat, wound and burn care, soothing minor skin irritation.Based on those ingredients, 736 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Manuka Honey Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Premium Gold Energy Manuka Honey Blend by ManukaGuard
Ask about any prescription or over-the-counter medication and we check it for interactions with Premium Gold Energy Manuka Honey Blend by ManukaGuard — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Premium Gold Energy Manuka Honey Blend by ManukaGuard
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: a manuka honey blend. Manuka honey is a special type of honey from New Zealand known for higher levels of certain compounds than regular honey.
There are no inactive fillers or other ingredients listed.
Does it work?
Insufficient evidence
The evidence shows manuka honey is possibly effective for several uses: cold sores, cough, mouth sores (oral mucositis), burns, and dry eye. That means there's some promising research, but we don't yet have enough data to call it proven.
If you're thinking about using it for one of these purposes, talk with your doctor or pharmacist about what the research actually supports and whether it makes sense for your situation.
How safe is it?
Well-documented data
Honey is generally well tolerated as a food for adults and children over 1 year of age. When used as a medicine, the most common side effects from taking it by mouth are nausea, stomach pain, and vomiting; topically you might notice burning, pain, or stinging.
Rare serious reactions can occur if honey contains grayanotoxins — a toxin from rhododendrons found in some honey from the Black Sea coast of Turkey — which can cause heart rhythm problems and low blood pressure. Allergic reactions including anaphylaxis are possible, as are local allergic reactions when applied to skin.
Honey is likely safe in pregnancy and lactation as a food; if you want to use it medicinally, check with your doctor or pharmacist first.
Meds to double-check
Moderate interaction found
Before you start, check with your doctor or pharmacist if you take phenytoin (Dilantin) for seizures — honey may theoretically increase its levels. Also double-check if you're on blood thinners (anticoagulants) or anti-platelet drugs, or if you take medications broken down by your liver through the CYP3A4 pathway, since the effects are unclear and vary by honey type.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking to soothe a cough, cold sore, or burn, manuka honey has some evidence on its side — though the research isn't definitive yet. Just check your medications first, especially if you take seizure drugs, blood thinners, or medications processed by your liver.
Talk with your doctor or pharmacist before using it as a medicine rather than just as food, and avoid honey from the Black Sea region of Turkey.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Premium Gold Energy Manuka Honey Blend, straight from the product label.
| Brand | ManukaGuard |
|---|---|
| Barcode (UPC) | 858631002203 |
| Net contents | 500 Gram(s); 17.6 oz. |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2016 |
| DSLD ID | 56396 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Premium Gold Energy Manuka Honey Blend by ManukaGuard, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 50 {Calories} | -- |
| Total Carbohydrates | 4 Gram(s) | 2% |
| Sugar | 4 Gram(s) | -- |
| Manuka Honey Blend | 5 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
ManukaGuard proprietary ENERGY BLEND of wild harvested New Zealand Manuka Honey USA harvested, USDA GRADE A Buckwheat & Orange Blossom Honey: Delivers sustained energy, supporting physical performance without the side effects of caffeine commonly found in energy products. Supports healthy gut flora and nourishes the digestive system.
Best Before: Batch:
WHOLE food
-Natural sugars convert to stored energy for sustained energy throughout the day -Supports body weight management -Supports overall gastric and digestive health
SUSTAINED ENERGY PLUS
MANUKA HONEY BLEND
Bottled in the USA with ingredients produced in USA & New Zealand. WILD HARVESTED GENUINE MANUKA HONEY.
Formula
Methylglyoxal 40 mg/kg MGO 40
ENERGY Energy content: -Contains about 7.5 times more energy than a high caffeine energy drink
MGO 40
Wild Harvested Genuine Manuka Honey.
Precautions
IF THIS HONEY CRYSTALIZES PLACE JAR IN HOT WATER UNTIL CRYSTALS DISSOLVE.
Not suitable for children under the age of 1 year.
Seals/Symbols
U
CAFEINE FREE DAILY SUSTAINABLE ENERGY
Formulation
HAS NO GENETICALLY-ENGINEERED INGREDIENTS
Suggested/Recommended/Usage/Directions
Directions: one to five teaspoons daily or as needed. Use with your favorite drinks.
FDA Disclaimer Statement
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Premium Gold Energy Manuka Honey Blend by ManukaGuard label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Premium Gold Energy Manuka Honey Blend by ManukaGuard
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 tsp Dosage formLiquid Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Manuka Honey Blend
Interacts with736 drugs
Honey is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade or Manuka...
Manuka Honey Blend monograph & interactionsPremium Gold Energy Manuka Honey Blend by ManukaGuard Drug Interactions
HelloPharmacist Interaction Report
Premium Gold Energy Manuka Honey Blend by ManukaGuard contains manuka honey, which has documented interactions with three medication types.
The most serious is phenytoin (Dilantin), an anti-seizure drug — honey may theoretically increase its blood levels, though this effect has only been shown in animals, not humans. The interaction is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Honey may also affect how your body processes drugs broken down by the liver enzyme CYP3A4 — though the evidence is mixed. Some studies suggest honey might decrease their levels, while others found no effect, and different honey preparations may behave differently.
This is rated Minor. Additionally, honey may theoretically increase bleeding risk if you take blood thinners (anticoagulants) or anti-platelet drugs, based on lab and animal data showing honey can slow clotting time — also Minor severity.
Altogether, these interactions span 737 individual medications. Because the research is limited and inconsistent, and because honey is a variable natural product, the safest move is to run your exact medications through the checker on this page before starting, especially if you take seizure medications, blood thinners, or drugs processed by the liver.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Premium Gold Energy Manuka Honey Blend?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Premium Gold Energy Manuka Honey Blend interact with 736 drugs. Click any drug to see the details.
1 of the 2 ingredients in Premium Gold Energy Manuka Honey Blend interact with drugs. Each result below shows which ingredient is responsible. Manuka Honey Blend
FosphenytoinCerebyx
How Fosphenytoin interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Manuka Honey Blend + Fosphenytoin interactionFosphenytoin SodiumSesquient
How Fosphenytoin Sodium interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Manuka Honey Blend + Fosphenytoin Sodium interactionMephenytoinMesantoin
How Mephenytoin interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Manuka Honey Blend + Mephenytoin interactionPhenobarbital, PhenytoinDilantin with PB
How Phenobarbital, Phenytoin interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Manuka Honey Blend + Phenobarbital, Phenytoin interactionPhenytoinDi-Phen, Dilantin, Dilantin Infatabs, Dilantin injection, Dilantin Kapseals, Phenytek
How Phenytoin interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, honey might increase levels of phenytoin.
Read the full Manuka Honey Blend + Phenytoin interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey Blend + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey Blend + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey Blend + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey Blend + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Premium Gold Energy Manuka Honey Blend — through 1 ingredient. Tap an ingredient for the detail:
Manuka Honey BlendCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey Blend + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Premium Gold Energy Manuka Honey Blend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Manuka Honey Blend
Phenytoin (Dilantin)
Theoretically, honey might increase levels of phenytoin.
In an animal model, the rate and extent of absorption of phenytoin was increased by honey. This effect has not been reported in humans.
Anticoagulant/Antiplatelet Drugs
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro, honey inhibits platelet aggregation and increases the time to clotting. Furthermore, animal research suggests that feeding mice large doses of honey for 12 days increases bleeding time when compared with no intervention. However, these effects have not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Some clinical research shows that honey induces CYP3A4. However, other clinical studies found no effect on CYP3A4 activity. Different honey preparations may have different effects on CYP3A4.
Brand information
Manufacturer and brand details for Premium Gold Energy Manuka Honey Blend, from the product label.
ManukaGuard
See all ManukaGuard products- Name
- Ndal Laboratories Ltd.
- Street Address
- P.O Box 590,
- City
- Monterey
- State
- CA
- ZipCode
- 93942
- Phone Number
- 1-800-916-1220
- Web Address
- www.ManukaGuard.com
Premium Gold Energy Manuka Honey Blend by ManukaGuard: Common Questions
Does Premium Gold Energy Manuka Honey Blend by ManukaGuard interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe for children?
Can I take this while breastfeeding?
What side effects might I experience?
Does this actually work for colds and coughs?
Is this the same as regular honey?
Where does this honey come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Premium Gold Energy Manuka Honey Blend is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Premium Gold Energy Manuka Honey Blend’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Premium Gold Energy Manuka Honey Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Honey 40 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Bose B. Honey or sugar in treatment of infected wounds? Lancet 1982;1:963. PubMed
- Ozhan H, Akdemir R, Yazici M, et al. Cardiac emergencies caused by honey ingestion: a single centre experience. Emerg Med J 2004;21:742-4. PubMed
- Centers for Disease Control. Botulism in the Unites Sates, 1899-1996. Handbook for epidemiologists, clinicians, and laboratory workers, 1998. Available online: http://www.cdc.gov/ncidod/dbmd/diseaseinfo/botulism.PDF.
- Simon A, Traynor K, Santos K, et al. Medical honey for wound care - still the 'latest resort'? Evid Based Complement Alternat Med 2009;6:165-73. PubMed
- Gethin G, Cowman S. Case series of use of Manuka honey in leg ulceration. Int Wound J 2005;2:10-15. PubMed
- Ingle R, Levin J, Polinder K. Wound healing with honey - a randomised controlled trial. S Afr Med J 2006;96:831-5.
- Johnson DW, van Eps C, Mudge DW, et al. Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients. J Am Soc Nephrol 2005;16:1456-62. PubMed
- Sukriti and Garg, S. K. Influence of honey on the pharmacokinetics of phenytoin in rabbits. Ind J Pharmacol 2002;34(147).
- Jung, A. and Ottosson, J. [Infantile botulism caused by honey]. Ugeskr Laeger 2001;163(2):169.
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