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Dietary supplement

Prune 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Prune 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prune 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prune 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for constipation, digestive health, bone health support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Prune. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prune 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Prune 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prune 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: prune (450 mg per capsule). Prunes are dried plums and have been used to support digestive health.

The capsule itself is made from gelatin and water, which are inactive ingredients that hold and deliver the prune inside.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and constipation support.
  • We looked for evidence on: Constipation, Postoperative ileus, Bowel regularity, Digestive comfort.
  • The strongest evidence on file: Plum is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Plum is rated "Insufficient Reliable Evidence To Rate" for Postoperative ileus.

The evidence supports prune as possibly effective for constipation — it's one of the better-studied uses. For bone health (osteopenia), cholesterol management (dyslipidemia), and liver health (hepatitis), the evidence isn't established well enough to rate it either way.

If you're considering this for constipation, the data backs it; for other uses, talk with your pharmacist about whether the science supports your goal.

The evidence, ingredient by ingredient Plum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Prunes and plums eaten as food are generally well tolerated and widely considered safe in normal amounts. The most common side effects are gastrointestinal — flatulence and diarrhea.

Serious side effects are rare but have been reported: allergic reactions and, in rare cases, bowel obstruction (especially if someone can't chew properly or swallows pits). Because this is a concentrated supplement form, not plain food, safety data in pregnancy and breastfeeding is limited.

If you're pregnant or nursing, talk with your doctor or pharmacist before starting it.

Side effects, ingredient by ingredient Plum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Plum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check if you're on any blood thinners or antiplatelet drugs — that's the main class to watch. Warfarin, aspirin, clopidogrel, and similar medications may be affected.

Use the medication checker on this page to search your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Prune is a solid choice if you're looking for help with constipation and you don't take blood thinners. If you're on any anticoagulant or antiplatelet medication, check with your pharmacist first — the interaction is real and worth talking through.

Expect mild digestive effects like gas or loose stool as a normal response.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prune 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435212056
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 289440
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prune 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435212056
IngredientAmount% DV
Prune450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prune 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prune 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prune 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Prune

Interacts with
122 drugs
450 mg per serving

Plums and their dried form (prunes) are common, nutritious foods that are best known for helping relieve constipation thanks to their fiber and sorbit...

Prune monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prune 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Prune 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Prune 122

Individual Drug Interactions

The ingredients in Prune 450 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Prune 450 mg interact with drugs. Each result below shows which ingredient is responsible. Prune

Each ingredient & the kinds of drugs it affects

For each ingredient in Prune 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Prune1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, plum juice might have antiplatelet effects.
Consuming plum juice while taking anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding. In healthy volunteers, drinking plum juice 200 mL daily for 28 days prolonged clotting time and inhibited platelet aggregation.

Likelihood Possible Evidence B
Prune full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prune 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Prune 450 mg by TerraVita Premium Collection: Common Questions

Does Prune 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Prune 450 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prune 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this really help my constipation?
Yes — prune is rated possibly effective for constipation, meaning the evidence supports it as a reasonable choice. That said, mild gastrointestinal side effects like gas or diarrhea are common, so start with a lower dose and see how your body responds.
Is it safe to take this if I'm on aspirin?
Not without talking to your pharmacist first. Prune has antiplatelet effects, and combining it with aspirin or other blood thinners could raise your bleeding risk. Bring your medication list in and we can figure out whether this is safe for you.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data on concentrated prune supplements in pregnancy or breastfeeding to know either way. Talk with your doctor or pharmacist for personalized advice — eating plain prunes as food is generally considered fine, but supplements are less studied.
What are the side effects I should watch for?
Most people tolerate prune well. The common ones are digestive — gas and loose stool. Serious side effects like allergic reactions are rare. If you have trouble chewing or swallow a pit by accident, there's a small risk of bowel obstruction, but that's unlikely with a capsule form.
Is this just dried plum in a capsule?
Yes, it's prune (dried plum) at 450 mg per capsule, plus gelatin and water to make the capsule itself. No fillers or unnecessary extras.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prune 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prune 450 mg label
Go deeper

The Full Monographs Behind Prune 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Plum

Interacts with 122 drugs

Plums and their dried form (prunes) are common, nutritious foods that are best known for helping relieve constipation thanks to their fiber and sorbitol content. They are generally safe as f...

Read the full Plum monograph →
Sources

Sources & How We Checked

Prune 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Plum 10 references
  1. Lever E, Cole J, Scott SM, Emery PW, Whelan K. Systematic review: the effect of prunes on gastrointestinal function. Aliment Pharmacol Ther. 2014;40(7):750-8. PubMed
  2. Hooshmand S, Chai SC, Saadat RL, et al. Comparative effects of dried plum and dried apple on bone in postmenopausal women. Br J Nutr. 2011;106(6):923-30. PubMed
  3. Ibrahim N, Chauhan I, Nikkar-Esfahani A. 'A problematic plum pit in the piping': a case of traumatic oesophageal perforation. BMJ Case Rep. 2016;2016. pii: bcr2015213807. PubMed
  4. Piirainen L, Peuhkuri K, Bäckström K, Korpela R, Salminen S. Prune juice has a mild laxative effect in adults with certain gastrointestinal symptoms. Nutr. Res. 2007;27(8):511-3. DOI
  5. Kong MS, Wang KL. A prune-induced small intestinal obstruction: sonographic appearance. J Clin Ultrasound. 1995;23(9):558-60. PubMed
  6. Jain M, Pielage P, De-Ryke R. Plum stones: an unusual cause of ileostomy obstruction demonstrated by sonography. J Clin Ultrasound. 1998;26(8):416-7. DOI
  7. Arjmandi BH, Khalil DA, Lucas EA, et al. Dried plums improve indices of bone formation in postmenopausal women. J Womens Health Gend Based Med. 2002;11(1):61-8. PubMed
  8. Santhakumar AB, Kundur AR, Fanning K, Netzel M, Stanley R, Singh I. Consumption of anthocyanin-rich Queen Garnet plum juice reduces platelet activation related thrombogenesis in healthy volunteers. J. Functional Foods. 2015;12:11-22. DOI
  9. Santhakumar AB, Kundur AR, Sabapathy S, Stanley R, Singh I. The potential of anthocyanin-rich Queen Garnet plum juice supplementation in alleviating thrombotic risk under induced oxidative stress conditions. J. Functional Foods. 2015;14:747-57. DOI
  10. Johnson MC, Fisher JK. Plum pit ileus: a case report. Mo Med. 1991;88(10):696-8.

See these in context on the Plum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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