pTeroBlue Pterostilbene Blueberry Complex 350 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking pTeroBlue Pterostilbene Blueberry Complex 350 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
pTeroBlue Pterostilbene Blueberry Complex 350 mg is a dietary supplement by Genceutic Naturals with 8 active ingredients. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 907 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Japanese Knotweed (Polygonum cuspidatum) (root) extract, Vaccinium uliginosum, Vaccinium myrtilloides. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 8 ingredients, several of which are active. The core is a wild Alaska blueberry blend — a mix of four Vaccinium (blueberry) species including Vaccinium uliginosum, Vaccinium cespitosum, Vaccinium membranaceum, and Vaccinium myrtilloides — plus Japanese Knotweed root extract (which contains resveratrol, an antioxidant compound) and pTeroPure trans-Pterostilbene, a stilbene compound related to resveratrol.
The inactive ingredients are rice flour, vegetable cellulose, vegetable magnesium stearate, and silicon dioxide, which serve as fillers and capsule material.
Does it work?
Couldn't assess
For the blueberry species in this product, the evidence is limited. Vaccinium uliginosum, Vaccinium cespitosum, and Vaccinium membranaceum all show insufficient reliable evidence for most uses — including age-related cognitive decline, macular degeneration, heart health, and cholesterol — and are rated possibly ineffective for night vision.
Vaccinium myrtilloides fares similarly across most claims (hypertension, cognitive health, anxiety, athletic performance, cholesterol, and heart disease are all either insufficient or possibly ineffective). For Japanese Knotweed, evidence is insufficient for the conditions tracked in our data — hepatitis, rheumatoid arthritis, wound healing, gout, osteoarthritis, and unstable angina.
We hold no effectiveness ratings for the pterostilbene ingredient.
How safe is it?
Well-documented data
The blueberry ingredients are generally well tolerated when taken as a supplement, though a small number of trial participants reported dark-colored or dark-green stools, flatulence, and mild gastrointestinal discomfort — and in one trial, about 26% of people taking freeze-dried blueberries dropped out in the first week due to stomach complaints. Discoloration of the tongue and even teeth has been observed in some users.
Japanese Knotweed safety data in supplements is limited; it contains emodin, which may cause digestive upset, and the safety notes advise caution because some compounds may affect the uterus or bowel. For pregnancy and breastfeeding, the blueberry components are rated Likely Safe, though concentrated supplements haven't been well studied in pregnancy and high-dose extracts' safety during breastfeeding is unknown.
Japanese Knotweed carries insufficient safety information and is advised against in pregnancy and breastfeeding.
Meds to double-check
Moderate interaction found
Check before starting if you take blood thinners (anticoagulants or antiplatelets like warfarin or aspirin) — blueberry and knotweed both may raise bleeding risk. Also verify if you're on diabetes medications (risk of low blood sugar), drugs metabolized by liver enzyme systems CYP1A2, CYP2C19, CYP3A4, or CYP2E1 (knotweed may increase their levels), estrogen therapy (knotweed may interfere), the pain reliever flurbiprofen, the anti-anxiety drug buspirone, or the seizure medication carbamazepine.
Talk it through with your doctor or pharmacist before adding this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a blueberry-and-knotweed blend with limited evidence for most health claims and Moderate interactions to watch — especially if you take blood thinners, diabetes drugs, or medications your liver processes through several enzyme systems. The blueberry parts are generally well tolerated, though they commonly cause dark stools and sometimes stomach upset.
Before you start, check your medications with a pharmacist or doctor, especially if you're on blood thinners, diabetes control, or any prescription that requires careful dosing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about pTeroBlue Pterostilbene Blueberry Complex 350 mg, straight from the product label.
| Brand | Genceutic Naturals |
|---|---|
| Barcode (UPC) | 896245001083 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2016 |
| DSLD ID | 57499 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| AuroraBlue Wild Alaska Blueberry | 50 mg | -- |
| Vaccinium ovalifolium | 0 NP | -- |
| Vaccinium alaskaense | 0 NP | -- |
| Vaccinium uliginosum | 0 NP | -- |
| Vaccinium cespitosum Michx. | 0 NP | -- |
| Vaccinium membranaceum Dougles ex Torr. | 0 NP | -- |
| Vaccinium myrtilloides | 0 NP | -- |
| pTeroPure trans-Pterostilbene | 50 mg | -- |
| Japanese Knotweed (Polygonum cuspidatum) (root) extract | 250 mg | -- |
Other ingredients: Rice Flour, Vegetable Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Next Generation Nutraceuticals
Next Generation trans-Pterostilbene (methylated Resveratrol) which has been shown in published studies to be more bioavailable and last longer in the body than resveratrol
Strongest when trans-Pterostilbene is combined with Resveratrol.
Seals/Symbols
pTeroPure
GREENER & CLEANER
Formulation
Vegetarian/Vegan
Gluten Free/Non GMO
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement for adults, take two (2) capsules daily with meals.
Brand IP Statement(s)
pTeroPure is a registered trademark of ChromaDex, Inc. AuroraBlue is a registered trademark of Denali BioTechnologies, Inc.
Formula
Advanced Blueberry Complex and Nature-Identical 99% Pure trans-Pterostilbene
Precautions
Warning: Keep out of reach of children.
Do not use if safety seal is damaged or missing.
If you are pregnant, nursing, taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.
Storage
Store at 15-30(0)C (59-86(0)F). Protect from heat, light and moisture.
General
27855 R1214
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
AuroraBlue Wild Alaska Blueberry
- › Vaccinium ovalifolium
- › Vaccinium alaskaense
- › Vaccinium uliginosum
- › Vaccinium cespitosum Michx.
- › Vaccinium membranaceum Dougles ex Torr.
- › Vaccinium myrtilloides
PTeroPure trans-Pterostilbene
Japanese Knotweed (Polygonum cuspidatum) (root) extract
Interacts with826 drugs
Hu Zhang (Japanese knotweed root) is a traditional Chinese herb that is one of the richest natural sources of resveratrol and emodin. Some lab and ear...
Japanese Knotweed (Polygonum cuspidatum) (root) extract monograph & interactionsOther (inactive) ingredients: Rice Flour, Vegetable Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals Drug Interactions
HelloPharmacist Interaction Report
pTeroBlue Pterostilbene Blueberry Complex by Genceutic Naturals contains several blueberry species and Japanese Knotweed extract that do interact with medications.
The most serious concern is Moderate-severity interactions through the blueberry and knotweed ingredients with blood thinners (anticoagulants/antiplatelets) — blueberry compounds may increase bleeding risk, and knotweed's resveratrol may have antiplatelet effects.
Read the full breakdown — every affected drug type, severity by severity
Beyond blood thinners, there are Moderate-severity interactions with drugs your liver metabolizes through several enzyme systems (CYP1A2, CYP2C19, CYP3A4, and CYP2E1) from the knotweed; blueberry may also affect CYP2E1 substrates. The knotweed can theoretically increase levels of these drugs, potentially raising side effects.
Additionally, both blueberry and knotweed may lower blood sugar when paired with diabetes medications (Moderate with blueberry species, Minor risk noted separately). Blueberry also has Minor interactions with the pain reliever flurbiprofen and the anti-anxiety drug buspirone, and knotweed may interfere with estrogen therapy and the seizure drug carbamazepine (Moderate for the latter).
We could not check three ingredients — Vaccinium ovalifolium, Vaccinium alaskaense, and pTeroPure trans-Pterostilbene — because we hold no data for them. Altogether, these interactions span 908 individual medications.
Use the medication checker on this page to verify your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against pTeroBlue Pterostilbene Blueberry Complex 350 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in pTeroBlue Pterostilbene Blueberry Complex 350 mg interact with 907 drugs. Click any drug to see the details.
3 of the 8 ingredients in pTeroBlue Pterostilbene Blueberry Complex 350 mg interact with drugs. Each result below shows which ingredient is responsible. Japanese Knotweed (Polygonum cuspidatum) (root) extract Vaccinium uliginosum Vaccinium myrtilloides
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Abciximab interactionVaccinium Membranaceum Dougles Ex Torr.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Abrocitinib interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2C19.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acarbose interactionVaccinium MyrtilloidesAntidiabetes Drugs Minor
Interaction Summary
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vaccinium Myrtilloides + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acenocoumarol interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Aspirin interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Aspirin, Caffeine interactionVaccinium Membranaceum Dougles Ex Torr.Anticoagulant/antiplatelet Drugs, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Butalbital interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Butalbital, Caffeine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Butalbital, Caffeine, Codeine interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Butalbital, Codeine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Butalbital, Codeine Phosphate interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Codeine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Codeine, Salicylamide interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Isometheptene interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Caffeine, Pyrilamine interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Vaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionJapanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with pTeroBlue Pterostilbene Blueberry Complex 350 mg — through 2 ingredients. Tap an ingredient for the detail:
Japanese Knotweed (polygonum Cuspidatum) (root) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Japanese Knotweed (polygonum Cuspidatum) (root) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionVaccinium Membranaceum Dougles Ex Torr.Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Vaccinium Membranaceum Dougles Ex Torr. + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in pTeroBlue Pterostilbene Blueberry Complex 350 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Japanese Knotweed (Polygonum cuspidatum) (root) extract
Anticoagulant/Antiplatelet Drugs
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Hu zhang contains the constituent resveratrol. Resveratrol seems to have antiplatelet effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Hu zhang contains the constituent resveratrol. In vitro research shows that resveratrol might inhibit the CYP1A2 enzyme. This interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2C19.
Hu zhang contains the constituent resveratrol. In vitro research shows that resveratrol might inhibit the CYP2C19 enzyme. This interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Hu zhang contains the constituent resveratrol. In vitro research shows that resveratrol might inhibit the CYP2E1 enzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Hu zhang contains the constituent resveratrol. In vitro research shows that resveratrol might inhibit the CYP3A4 enzyme. However, a clinical study in adults with NAFLD found that adding resveratrol 3000 mg daily for 8 weeks did not necessitate dose adjustments to any established medications metabolized by CYP3A4.
Estrogens
Theoretically, hu zhang might competitively inhibit the effects of estrogen replacement therapy.
In vitro research shows that hu zhang might have estrogenic activity.
Carbamazepine (Tegretol)
Theoretically, hu zhang might increase the effects and adverse effects of carbamazepine.
In animals, blood and tissue levels of carbamazepine were increased when given in combination with hu zhang. It is thought that increased levels of carbamazepine are due to cytochrome P450 3A4 (CYP3A4) inhibition. This interaction has not been reported in humans.
Vaccinium uliginosum
Anticoagulant/Antiplatelet Drugs
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.
Erlotinib (Tarceva)
Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.
Vaccinium myrtilloides
Antidiabetes Drugs
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.
Buspirone (Buspar)
Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.
Flurbiprofen (Ansaid, Others)
Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.
Brand information
Manufacturer and brand details for pTeroBlue Pterostilbene Blueberry Complex 350 mg, from the product label.
Genceutic Naturals
See all Genceutic Naturals products- Name
- Genceutic Naturals
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- 1-800-872-0370
- Web Address
- www.Genceutic.com
pTeroBlue Pterostilbene Blueberry Complex 350 mg by Genceutic Naturals: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind pTeroBlue Pterostilbene Blueberry Complex 350 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bilberry
Interacts with 275 drugsBilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...
Read the full Bilberry monograph → Herb & supplement monographBlueberry
Interacts with 88 drugsBlueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...
Read the full Blueberry monograph → Herb & supplement monographHu Zhang
Interacts with 826 drugsHu Zhang (Japanese knotweed root) is a traditional Chinese herb that is one of the richest natural sources of resveratrol and emodin. Some lab and early human research looks interesting for...
Read the full Hu Zhang monograph →Sources & How We Checked
pTeroBlue Pterostilbene Blueberry Complex 350 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bilberry 14 references
- Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
- Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
- Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
- Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
- Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
- Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
- Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
- Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
- Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
- Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
- Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
- Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
- Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
- Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed
Blueberry 7 references
- Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
- Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
- Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
- Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
- Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
- Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
- Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed
Hu Zhang 19 references
- Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
- Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
- Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
- Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
- Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
- Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
- Matsuda H, Shimoda H, Morikawa T, Yoshikawa M. Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorg Med Chem Lett 2001;11:1839-42. PubMed
- Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
- Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
- Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
- Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
- Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
- Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
- Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
- Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
- Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
- Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
- Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
- Chi YC, Lin SP, Hou YC. A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats. Toxicol Appl Pharmacol 2012;263(3):315-22. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC