Pure Protein Fiber Mix Unflavored Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pure Protein Fiber Mix Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pure Protein Fiber Mix Unflavored is a dietary supplement by Creative Bioscience with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,036 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dietary Fiber, Acacia Fiber powder, Whey Protein isolate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pure Protein Fiber Mix Unflavored by Creative Bioscience
Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Protein Fiber Mix Unflavored by Creative Bioscience — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pure Protein Fiber Mix Unflavored by Creative Bioscience
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This powder has 2 active ingredients: whey protein isolate and acacia fiber powder. Whey protein is a complete protein source that's been studied most for athletic performance.
Acacia fiber is a soluble fiber, though we don't have effectiveness data on file for it in this product. There are no inactive ingredients listed.
Does it work?
Strong evidence
Whey protein isolate is possibly effective for athletic performance. For other uses — osteoporosis, COPD, cognitive decline, and HIV/AIDS-related wasting — the evidence either doesn't support it or isn't established.
We don't have effectiveness data on file for acacia fiber powder.
How safe is it?
Well-documented data
Whey protein is generally well tolerated by healthy adults when used as directed. The most common side effects are dose-related and include acne, bloating, cramps, diarrhea, fatigue, headache, nausea, reflux, reduced appetite, and thirst.
Whey protein has been linked to the onset or worsening of acne in case reports of teenagers and young adults; acne typically cleared after stopping the product. Because concentrated whey supplements are not well studied, check with your doctor before starting.
We have no pregnancy or lactation safety data on file for either ingredient — talk with your pharmacist or doctor for personalized advice.
Meds to double-check
Major interaction found
If you take levodopa (Parkinson disease), quinolone antibiotics, tetracycline antibiotics, or bisphosphonates, double-check this product with your pharmacist before starting — whey protein can interfere with how your body absorbs these medications.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This product is mainly useful if you're training hard and looking to add protein to your routine. If you take levodopa for Parkinson disease or any antibiotic or bone-health medication, check with your pharmacist before using it — timing matters to avoid reduced drug absorption.
Because concentrated whey supplements aren't well studied, it's worth a quick conversation with your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pure Protein Fiber Mix Unflavored, straight from the product label.
| Brand | Creative Bioscience |
|---|---|
| Barcode (UPC) | 816907011793 |
| Net contents | 1 lb; 450 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 21, 2017 |
| DSLD ID | 79199 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pure Protein Fiber Mix Unflavored by Creative Bioscience, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 65 Calorie(s) | -- |
| Dietary Fiber | 5 Gram(s) | 20% |
| Protein | 10 Gram(s) | 20% |
| Carbohydrates | 6 Gram(s) | 2% |
| Whey Protein isolate | 11.4 Gram(s) | -- |
| Acacia Fiber powder | 6.6 Gram(s) | -- |
Other ingredients: None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Warning: Use only as suggested.
Not intended for use by anyone under the age of 18, pregnant, nursing, and/or if the packaging is broken.
Not intended for use by anyone under the age of 18, pregnant, nursing, and/or if the packaging is broken.
Not intended for use by anyone under the age of 18, pregnant, nursing, and/or if the packaging is broken. Consult a physician before use if you or a family member has been diagnosed with any medical condition. Discontinue use and contact a physician if you experience any unusual symptoms.
Keep out of reach of children.
Contains: Dairy and soy.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
cb
25 servings
Formulation
Unflavored & rBGH free No artificial ingredients
GMO Free Gluten Free Sugar Free
Seals/Symbols
GMO Free Gluten Free Sugar Free
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Mix 1 scoop with 8 oz of water, juice or other beverage. For optimal results, take post exercise. Additional servings may be taken as needed for additional protein and fiber. Due to fiber content, be sure to drink plenty of additional fluids throughout the day.
Formula
Contains: Dairy and soy.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pure Protein Fiber Mix Unflavored by Creative Bioscience label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pure Protein Fiber Mix Unflavored by Creative Bioscience
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size18 Gram(s) Dosage formPowder Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
Carbohydrates
Whey Protein isolate
Interacts with53 drugs
Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined...
Whey Protein isolate monograph & interactionsAcacia Fiber powder
Interacts with2,022 drugs
Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplement for dige...
Acacia Fiber powder monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Pure Protein Fiber Mix Unflavored by Creative Bioscience Drug Interactions
HelloPharmacist Interaction Report
Pure Protein Fiber Mix Unflavored by Creative Bioscience contains whey protein isolate, which interacts with several medication types.
The most serious interaction is with levodopa (a medication for Parkinson disease): whey protein may decrease how much levodopa your body absorbs, and studies show that protein taken alongside levodopa can make tremor, stiffness, and the "on-off" effect worse.
Read the full breakdown — every affected drug type, severity by severity
Whey protein also contains minerals like calcium that can bind to and reduce absorption of three antibiotic types: quinolone antibiotics (take them at least 2 hours before or 4–6 hours after this product), tetracycline antibiotics (same timing), and bisphosphonates used for bone health (take at least 30 minutes before, ideally at a different time of day). All three interactions are rated Moderate.
We could not check acacia fiber powder — we hold no interaction data for it. Altogether, these interactions span 53 individual medications.
Use the medication checker below to see if any of your prescriptions are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pure Protein Fiber Mix Unflavored?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pure Protein Fiber Mix Unflavored interact with 2,036 drugs. Click any drug to see the details.
3 of the 4 ingredients in Pure Protein Fiber Mix Unflavored interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Acacia Fiber powder Whey Protein isolate
Benserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Pure Protein Fiber Mix Unflavored — through 3 ingredients. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Benserazide, Levodopa interactionAcacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Benserazide, Levodopa interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Pure Protein Fiber Mix Unflavored — through 3 ingredients. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Carbidopa, Levodopa interactionAcacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Carbidopa, Levodopa interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Pure Protein Fiber Mix Unflavored — through 3 ingredients. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Carbidopa, Levodopa, Entacapone interactionAcacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Carbidopa, Levodopa, Entacapone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbidopa, Levodopa, Entacapone interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Pure Protein Fiber Mix Unflavored — through 3 ingredients. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Levodopa interactionAcacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Levodopa interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Pure Protein Fiber Mix Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Levodopa, Carbidopa interaction"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + "phentolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abacavir interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abacavir Sulfate, Dolutegravir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abacavir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abciximab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abemaciclib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abiraterone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abiraterone Acetate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acalabrutinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acamprosate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acenocoumarol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acepromazine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Butalbital, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Pure Protein Fiber Mix Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Acacia Fiber PowderOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Fiber Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine Phosphate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pure Protein Fiber Mix Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Acacia Fiber powder
Amoxicillin (Amoxil, Trimox)
Gum arabic can reduce the absorption of amoxicillin.
A small study in healthy volunteers shows that taking amoxicillin and gum arabic concurrently significantly reduces the absorption of amoxicillin. Separate doses of amoxicillin from gum arabic by at least 2 hours.
Oral Drugs
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Gum arabic has been used as a suspending osmotic agent in drug formulations. It might improve bioavailability of water-insoluble drugs like naproxen, but reduce absorption of polar drugs like amoxicillin. To avoid changes in absorption, take gum arabic 30-60 minutes after oral medications.
Whey Protein isolate
Levodopa
Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.
Bisphosphonates
Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.
Quinolone Antibiotics
Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.
Tetracycline Antibiotics
Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.
Brand information
Manufacturer and brand details for Pure Protein Fiber Mix Unflavored, from the product label.
Creative Bioscience
See all Creative Bioscience products- Name
- Creative Bioscience
- Street Address
- 4530 South 300 West
- City
- Murray
- State
- UT
- ZipCode
- 84107
- Phone Number
- 877-744-1224
- Web Address
- www.creativebioscience.com
Pure Protein Fiber Mix Unflavored by Creative Bioscience: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pure Protein Fiber Mix Unflavored’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographWhey Protein
Interacts with 53 drugsWhey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...
Read the full Whey Protein monograph → Herb & supplement monographGum Arabic
Interacts with 2,022 drugsGum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplement for digestive health and as a prebiotic. Early s...
Read the full Gum Arabic monograph →Sources & How We Checked
Pure Protein Fiber Mix Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 51 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Whey Protein 25 references
- Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
- Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
- Bell SJ. Whey protein concentrates with and without immunoglobulins: a review. J Med Food 2000;3:1-13. PubMed
- Nutt JG, Woodward WR, Hammerstad JP, et al. The "on-off" phenomenon in Parkinson's disease. Relation to levodopa absorption and transport. N Engl J Med 1984;310:483-8. PubMed
- Baruzzi A, Contin M, Riva R, et al. Influence of meal ingestion time on pharmacokinetics of orally administered levodopa in parkinsonian patients. Clin Neuropharmacol 1987;10:527-37. PubMed
- Juncos JL, Fabbrini G, Mouradian MM, et al. Dietary influences on the antiparkinsonian response to levodopa. Arch Neurol 1987;44:1003-5. PubMed
- Eriksson T, Granerus AK, Linde A, et al. "On-off" phenomenon in Parkinson's disease: relationship between dopa and other large neutral amino acids in plasma. Neurology 1988;38:1245-8. PubMed
- Semla TP, Beizer JL, Higbee MD. Geriatric Dosage Handbook. 4th ed. Hudson, OH: Lexicomp, 1998.
- Pletz MW, Petzold P, Allen A, et al. Effect of calcium carbonate on bioavailability of orally administered gemifloxacin. Antimicrob Agents Chemother 2003;47:2158-60.. PubMed
- Peters ML, Leonard M, Licata AA. Role of alendronate and risedronate in preventing and treating osteoporosis. Cleve Clin J Med 2001;68:945-51. PubMed
- Micke, P., Beeh, K. M., and Buhl, R. Effects of long-term supplementation with whey proteins on plasma glutathione levels of HIV-infected patients. Eur.J Nutr 2002;41(1):12-18. PubMed
- Chitapanarux, T., Tienboon, P., Pojchamarnwiputh, S., and Leelarungrayub, D. Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. J Gastroenterol.Hepatol. 2009;24(6):1045-1050. PubMed
- Sataloff, R. T., Bittermann, T., Marks, L., Lurie, D., and Hawkshaw, M. The effects of glutathione enhancement on sensorineural hearing loss. Ear Nose Throat J 2010;89(9):422-433.
- Zhu, K., Meng, X., Kerr, D. A., Devine, A., Solah, V., Binns, C. W., and Prince, R. L. The effects of a two-year randomized, controlled trial of whey protein supplementation on bone structure, IGF-1, and urinary calcium excretion in older postmenopausal
- Bjorkman, M. P., Pilvi, T. K., Kekkonen, R. A., Korpela, R., and Tilvis, R. S. Similar effects of leucine rich and regular dairy products on muscle mass and functions of older polymyalgia rheumatica patients: a randomized crossover trial. J Nutr Health A
- Brun, A. C., Stordal, K., Johannesdottir, G. B., Bentsen, B. S., and Medhus, A. W. The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. Clin.Nutr 2012;31(1):108-112. PubMed
- Gouni-Berthold, I., Schulte, D. M., Krone, W., Lapointe, J. F., Lemieux, P., Predel, H. G., and Berthold, H. K. The whey fermentation product malleable protein matrix decreases TAG concentrations in patients with the metabolic syndrome: a randomised plac
- Errichiello, L., Pezzella, M., Santulli, L., Striano, S., Zara, F., Minetti, C., Mainardi, P., and Striano, P. A proof-of-concept trial of the whey protein alfa-lactalbumin in chronic cortical myoclonus. Mov Disord. 2011;26(14):2573-2575. PubMed
- Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., and Nicholson, C. The randomized comparative pediatric critical illness stress-induced immune suppres
- Chungchunlam, S. M., Moughan, P. J., Henare, S. J., and Ganesh, S. Effect of time of consumption of preloads on measures of satiety in healthy normal weight women. Appetite 2012;59(2):281-288. PubMed
- Rencuzogullari I, Börekçi A, Karakoyun S, et al. Coronary thrombosis in three coronary arteries due to whey protein. Am J Emerg Med. 2017;35(4):664.e3-664.e4. PubMed
- Silverberg NB. Whey protein precipitating moderate to severe acne flares in 5 teenaged athletes. Case Reports Cutis. 2012;90(2):70-2.
- Simonart T. Acne and whey protein supplementation among bodybuilders. Dermatology. 2012;225(3):256-8. PubMed
- Pontes TC, Costa Fernandes Filho GM, Pereira Trindade AS, Sobral Filho JF. Incidence of acne vulgaris in young adult users of protein-calorie supplements in the city of João Pessoa-PB. An Bras Dermatol. 2013;88(6):907-12.
- Adebamowo CA, Spiegelman D, Berkey CS, et al. Milk consumption and acne in teenaged boys. J Am Acad Dermatol. 2008 May;58(5):787-93. PubMed
Gum Arabic 8 references
- Jensen CD, Spiller GA, Gates JE, et al. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12:147-54. PubMed
- Eltayeb IB, Awad AI, Elderbi MA, Shadad SA. Effect of gum arabic on the absorption of a single oral dose of amoxicillin in healthy Sudanese volunteers. J Antimicrob Chemother 2004;54:577-8. PubMed
- Babiker R, Merghani TH, Elmusharaf K, et al. Effects of gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr J 2012;11:111. PubMed
- Babiker R, Elmusharaf K, Keogh MB, Banaga AS, Saeed AM. Metabolic effect of gum Arabic (Acacia senegal) in patients with type 2 diabetes mellitus (T2DM): randomized, placebo controlled double blind trial. Functional Foods in Health and Disease. 2017;7(3): DOI
- Beneke CE, Viljoen AM, Hamman JH. Polymeric plant-derived excipients in drug delivery. Molecules. 2009;14(7):2602-20. PubMed
- Ali NE, Kaddam LA, Alkarib SY, et al. Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial. Int J Nephrol. 2020;2020:7214673.
- Mortensen A, Aguilar F, Crebelli R, et al. Re-evaluation of acacia gum (E 414) as a food additive. EFSA J. 2017;15(4):e04741. PubMed
- Larson R, Nelson C, Korczak R, et al. Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects. Nutrients 2021;13(2):618. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC