RapidDrive Pre-Workout Amino Complex Fruit Punch Ingredients & Drug Interactions
What is this page for?
First and foremost: checking RapidDrive Pre-Workout Amino Complex Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
RapidDrive Pre-Workout Amino Complex Fruit Punch is a dietary supplement by GNC Pro Performance with 9 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 192 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Micronized L-Taurine, micronized L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance
Ask about any prescription or over-the-counter medication and we check it for interactions with RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This powder contains 9 active ingredients, most of them branched-chain amino acids and related compounds meant to support muscle performance and endurance during exercise. You're getting L-isoleucine, L-valine, L-leucine (all in micronized form for absorption), plus L-arginine, citrulline, beta-alanine, taurine, and L-carnitine.
These are paired with inactive ingredients like citric acid, malic acid, and sucralose for flavor and texture.
Does it work?
Moderate evidence
Beta-alanine is rated possibly effective for athletic performance and physical performance based on available evidence. L-carnitine is effective for L-carnitine deficiency itself, and possibly effective for congestive heart failure, high cholesterol, and angina.
Taurine is possibly effective for hepatitis and congestive heart failure, though the evidence on most uses in this product—and on the amino acids themselves—isn't established in our data. Beta-alanine has insufficient evidence for cognitive function, age-related cognitive decline, chronic lung disease, and menopausal symptoms.
How safe is it?
Well-documented data
Beta-alanine is generally well tolerated but commonly causes harmless tingling and flushing of the skin, usually starting on the scalp within 20 minutes and lasting about an hour—it's dose-dependent and mild at lower doses. Taurine and L-carnitine are generally well tolerated at typical doses short-term, though L-carnitine can cause stomach upset, nausea, diarrhea, and rarely a fishy body odor.
Long-term safety data on taurine is less certain, and L-carnitine hasn't been well studied at high doses. Beta-alanine should be avoided in pregnancy and breastfeeding due to insufficient safety data.
Taurine is likely safe in pregnancy but caution is advised while breastfeeding. L-carnitine's safety in pregnancy isn't on file, and breastfeeding safety is possibly safe but not well studied.
Meds to double-check
Moderate interaction found
Check before starting if you take blood thinners like warfarin or acenocoumarol (moderate risk of increased bleeding), blood pressure medications (moderate risk of blood pressure dropping too low), lithium for bipolar disorder (moderate risk of lithium buildup), or thyroid hormone replacement (moderate risk of reduced effectiveness). Several ingredients here we couldn't check, so run your complete medication list through the search tool on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This pre-workout is aimed at people doing strength or endurance training who want amino acid support. If you take blood thinners, blood pressure medications, lithium, or thyroid hormone, you'll need to check with your doctor or pharmacist before starting—the interactions are real and worth discussing.
The skin tingling from beta-alanine is normal and harmless, but it's not for everyone. Talk it over with your own doctor or pharmacist before you add it to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about RapidDrive Pre-Workout Amino Complex Fruit Punch, straight from the product label.
| Brand | GNC Pro Performance |
|---|---|
| Barcode (UPC) | 048107090838 |
| Net contents | 10.92 oz.; 310 g |
| Market status | On market |
| Date entered into DSLD | Dec 23, 2011 |
| DSLD ID | 2722 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 {Calories} | -- |
| Total Carbohydrates | 1 g | 1% |
| L-Isoleucine, Micronized | 1000 mg | -- |
| L-Valine, Micronized | 1000 mg | -- |
| L-Arginine, Micronized | 1000 mg | -- |
| L-Leucine, Micronized | 3000 mg | -- |
| Citrulline, Micronized | 50 mg | -- |
| Beta-Alanine, Micronized | 3200 mg | -- |
| Micronized L-Taurine | 1000 mg | -- |
| micronized L-Carnitine | 500 mg | -- |
| Micronized alpha-Ketogluarate | 100 mg | -- |
Other ingredients: Natural and Artificial flavors, Citric Acid, Malic Acid, Lecithin, Sucralose, FD&C Red #40
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
DIRECTIONS: As a dietary supplement, mix one scoop (15.5 g) with 8 fl.oz. of water before each workout.
Precautions
KEEP OUT OF REACH OF CHILDREN.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place.
Formula
CONTAINS: Soybeans.
General Statements
AMINO SERIES
Combines micronized L-arginine with micronized citrulline, key precursors to nitric oxide (N.O.) to get you those extreme pre-workout pumps!*
GNC's Product Development Scientists were challenged to create an advanced delivery form of amino acid supplements, a critical sports nutrition component that can be used in the regimen of top athletes.
LOADED WITH 7 GRAMS OF AMINOS, BETA-ALANINE & CITRULLINE
MICRONIZED FORMULA DESIGNED TO ENHANCE FATIGUE-CONTROLLING FACTORS*
Natural and Artificial Flavor
New
Notice: Significant product settling may occur.
Pro Performance(R) RapidDrive(TM) Pre-Workout Amino complex feathures our most advanced RapidDrive(TM) Amino Acid technology. This formula has been scientifically designed to provide your body with the most important amino acids needed before exercise.
Supplies a 3:1:1 ration of micronized branched chain amino acids (BCAA) to help reduce protein breakdown, preserve glycogen stores and stimulate muscle protein syntheses.*
The result of these research efforts led to the creation of the RapidDrive(TM) Amino Series, a core group of superor and fast-absorbing amino acids for rapid muscle fuel.
These ingredients have been pulverized, or "micronized," from large molecules into smaller particles that are easier to absorb and facilitate fast fuel for powerful performance.* It features micronized beta-alanine which stimulates muscle carnosine levels - a key fatigue-controlling factor.*
This formula is sugar-free and stimulant-free so it can be taken any time, day or night.
This supreme amino formula is also equipped with L-carnitine to help convert fatty acids into energy and alpha-ketogluarate (AKG) which is important for amino acid availablilty and protein synthesis.*
This unique technology is much more advanced compared to regular amino acids. Because our team is dedicated to continually improving sports nutrition products, the Pro Performance(R) RapidDrive(TM) Amino Series helps you, the athlete, get fast fuel for your muscles.
Use of beta-Alanine are licensed from Natural Alternatives International, Inc. under U.S. Patents 5,965,596; 6,172,098; and 6,426,361B2.
General
CODE 351195 JKG
Formulation
No Sugar.
ZERO-SUGAR, STIMULANT FREE
Seals/Symbols
CarnoSyn(TM) Carnosine Synthesizer
FDA Statement of Identity
DIETARY SUPPLEMENT
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size15.5 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Isoleucine, Micronized
L-Valine, Micronized
L-Arginine, Micronized
L-Leucine, Micronized
Citrulline, Micronized
Beta-Alanine, Micronized
No knowninteractions
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...
Beta-Alanine, Micronized monograph & interactionsMicronized L-Taurine
Interacts with173 drugs
Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...
Micronized L-Taurine monograph & interactionsMicronized L-Carnitine
Interacts with19 drugs
L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...
Micronized L-Carnitine monograph & interactionsMicronized alpha-Ketogluarate
Other (inactive) ingredients: Natural and Artificial flavors, Citric Acid, Malic Acid, Lecithin, Sucralose, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.
RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance Drug Interactions
HelloPharmacist Interaction Report
RapidDrive Pre-Workout Amino Complex by GNC Pro Performance does interact with medications, primarily through its taurine and L-carnitine content.
The most serious documented concern is a moderate-severity interaction between L-carnitine and blood thinners like warfarin (Coumadin) and acenocoumarol (Sintrom), where L-carnitine may increase bleeding risk by enhancing their anticoagulant effects.
Read the full breakdown — every affected drug type, severity by severity
Taurine may lower blood pressure when combined with blood pressure medications (antihypertensives), raising the risk of blood pressure dropping too far. It also theoretically may increase lithium levels, which is a concern if you take lithium for bipolar disorder—taurine's diuretic-like properties might reduce how your kidneys clear it.
L-carnitine may also interfere with thyroid hormone replacement therapy by blocking how your cells take up thyroid hormones, potentially reducing the medication's effectiveness. Altogether, these interactions span 192 individual medications.
Several ingredients—L-isoleucine, L-valine, L-arginine, L-leucine, citrulline, and alpha-ketoglutarate—we could not check because we hold no interaction data for them. Before you start this product, run your exact medications through the search tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against RapidDrive Pre-Workout Amino Complex Fruit Punch?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in RapidDrive Pre-Workout Amino Complex Fruit Punch interact with 192 drugs. Click any drug to see the details.
2 of the 9 ingredients in RapidDrive Pre-Workout Amino Complex Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Micronized L-Taurine micronized L-Carnitine
BumetanideBurinex
How Bumetanide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Bumetanide (oral) interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptoprilAcepril, Capoten
How Captopril interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Captopril, Hydrochlorothiazide interactionCarteololCartrol, Ocupress
How Carteolol interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Carteolol interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Carvedilol interactionCeliprololCelicard
How Celiprolol interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Celiprolol interactionChlorothiazideDiuril
How Chlorothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Chlorthalidone, Clonidine interactionCilazaprilInhibace
How Cilazapril interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Cilazapril interactionClevidipineCleviprex
How Clevidipine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Clevidipine interactionClonidineCatapres
How Clonidine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Clonidine interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-carnitineThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full Micronized L-carnitine + Conjugated Estrogens interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Cyclothiazide interactionDeserpidineHarmonyl
How Deserpidine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Deserpidine interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Deserpidine, Methyclothiazide interactionDesiccated Thyroid ExtractWesthroid, WP Thyroid
How Desiccated Thyroid Extract interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-carnitineThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full Micronized L-carnitine + Desiccated Thyroid Extract interactionDesiccated Thyroid Extract (prescription Drug)Nature-Throid, Thyrar
How Desiccated Thyroid Extract (prescription Drug) interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-carnitineThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full Micronized L-carnitine + Desiccated Thyroid Extract (prescription Drug) interactionDextrothyroxineCholoxin
How Dextrothyroxine interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-carnitineThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full Micronized L-carnitine + Dextrothyroxine interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Diltiazem, Enalapril interactionDoxazosin MesylateCardura
How Doxazosin Mesylate interacts with RapidDrive Pre-Workout Amino Complex Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Micronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Doxazosin Mesylate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in RapidDrive Pre-Workout Amino Complex Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Micronized L-Taurine
Antihypertensive Drugs
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.
Lithium
Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.
micronized L-Carnitine
Acenocoumarol (Sintrom)
Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.
Thyroid Hormone
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.
Warfarin (Coumadin)
Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.
Brand information
Manufacturer and brand details for RapidDrive Pre-Workout Amino Complex Fruit Punch, from the product label.
RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance: Common Questions
Does RapidDrive Pre-Workout Amino Complex Fruit Punch by GNC Pro Performance interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this cause that tingling feeling I've heard about?
Is it safe to take while I'm pregnant or breastfeeding?
Can this cause stomach problems?
Does beta-alanine actually work for workouts?
What is L-carnitine supposed to do?
What do the amino acids in this do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if RapidDrive Pre-Workout Amino Complex Fruit Punch is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind RapidDrive Pre-Workout Amino Complex Fruit Punch’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Beta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph → Herb & supplement monographTaurine
Interacts with 173 drugsTaurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...
Read the full Taurine monograph → Herb & supplement monographL-carnitine
Interacts with 19 drugsL-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...
Read the full L-carnitine monograph →Sources & How We Checked
RapidDrive Pre-Workout Amino Complex Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 75 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-alanine 13 references
- Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
- Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
- Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
- Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
- Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
- Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
- Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
- Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
- Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
- Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
- da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
- Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
- Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed
Taurine 21 references
- Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
- Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
- Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
- Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
- Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
- Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
- Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
- Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
- Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
- Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
- Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
- Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
- Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
- Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
- Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
- Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
- Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
- Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
- Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
- Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
- Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed
L-carnitine 41 references
- Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
- Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
- Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
- Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
- Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
- Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
- Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
- Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
- 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
- Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
- Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
- Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
- Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
- Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
- Angelova-Fischer I, Rippke F, Fischer TW, Neufang G, Zillikens D. A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne. J Eur Acad Dermatol Venereol. 2013 Jul PubMed
- Hatamkhani S, Khalili H, Karimzadeh I, Dashti-Khavidaki S, Abdollahi A, Jafari S. Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial. J Gastroenterol. Hepatol. 2014 May;29(5):997-1004. PubMed
- Boehm G, Stahl B. Oligosaccharides from milk. J Nutr 2007;137(3 Suppl 2):847S-849S.
- Van Oudheusden, L. J. and Scholte, H. R. Efficacy of carnitine in the treatment of children with attention-deficit hyperactivity disorder. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(1):33-38. PubMed
- Derosa, G., Cicero, A. F., Gaddi, A., Mugellini, A., Ciccarelli, L., and Fogari, R. The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. Clin Ther 2003;25(5):1429-1439. PubMed
- Foitzik, K., Hoting, E., Heinrich, U., Tronnier, H., and Paus, R. Indications that topical L-carnitin-L-tartrate promotes human hair growth in vivo. J Dermatol.Sci 2007;48(2):141-144. PubMed
- Kumar, A., Singh, R. B., Saxena, M., Niaz, M. A., Josh, S. R., Chattopadhyay, P., Mechirova, V., Pella, D., and Fedacko, J. Effect of carni Q-gel (ubiquinol and carnitine) on cytokines in patients with heart failure in the Tishcon study. Acta Cardiol. 20
- Cruciani, R. A., Dvorkin, E., Homel, P., Culliney, B., Malamud, S., Lapin, J., Portenoy, R. K., and Esteban-Cruciani, N. L-carnitine supplementation in patients with advanced cancer and carnitine deficiency: a double-blind, placebo-controlled study. J Pa PubMed
- Malaguarnera, M., Vacante, M., Avitabile, T., Malaguarnera, M., Cammalleri, L., and Motta, M. L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes. Am J Clin.Nutr 2009;89(1):71-76. PubMed
- Alvarez, T. M., Guardiola, P. D., Roldan, J. O., Elviro, R., Wevers, R., and Guijarro, G. [Primary trimethylaminuria: the fish odor syndrome]. Endocrinol.Nutr. 2009;56(6):337-340.
- Wu, Z. M., Lu, X., Wang, Y. W., Sun, J., Tao, J. W., Yin, F. H., and Cheng, H. J. [Short-term medication of L-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia]. Zhonghua Nan.Ke.Xue 2012;18(3):253-256.
- Tarighat, Esfanjani A., Mahdavi, R., Ebrahimi, Mameghani M., Talebi, M., Nikniaz, Z., and Safaiyan, A. The effects of magnesium, L-carnitine, and concurrent magnesium-L-carnitine supplementation in migraine prophylaxis. Biol.Trace Elem.Res 2012;150(1-3): PubMed
- DiNicolantonio, J. J., Lavie, C. J., Fares, H., Menezes, A. R., and O'Keefe, J. H. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013;88(6):544-551. PubMed
- Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. B. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract
- Madsen KL, Preisler N, Orngreen MC, Andersen SP, Olesen JH, Lund AM, Vissing J. Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation. J Clin Endocri
- Prohaska ES, Muzyk AJ, Rivelli SK. Levocarnitine-induced hypophosphatemia in a hemodialysis patient with acute valproic acid toxicity. J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):E18-9. PubMed
- Shang R, Sun Z, Li H. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2014 Jul 21;14:88. PubMed
- Zhang JJ, Wu ZB, Cai YJ, Ke B, Huang YJ, Qiu CP, Yang YB, Shi LY, Qin J. L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study. Nutr J. 2014 Nov 26;13:110. PubMed
- Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL. Intestinal microbiota metabolism of L-carn
- Jun DW, Kim BI, Cho YK, Kim HJ, Kwon YO, Park SY, Han SY, Baek YH, Jung YJ, Kim HY, Kim W, Heo J, Woo HY, Hwang SG, Rim KS, Choi JY, Bae SH, Lee YS, Lim YS,Cheong JY, Cho SW, Lee BS, Kim SH, Sohn JH, Kim TY, Paik YH, Kim JK, Lee KS. Efficacy and safety of
- An JH, Kim YJ, Kim KJ, et al. L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial. Endocr J. 2016;63(10):885-95. PubMed
- Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 2017;3:CD009374. PubMed
- Khajeh B, Dashti-Khavidaki S, Nasiri-Toosi M, Mohammadi K, Jafari A. Effects of pre-transplant L-carnitine supplementation on primary graft dysfunction in liver transplant recipients: a pilot, randomized, placebo-controlled clinical trial. Res Pharm Sci. PubMed
- Kubota K, Uojima H, Shao X, et al. Additional L-carnitine Reduced the Risk of Hospitalization in Patients with Overt Hepatic Encephalopathy on Rifaximin. Dig Dis 2021. PubMed
- Amini L, Yaghini O, Ghazavi M, Aslani N. L-carnitine versus propranolol for pediatric migraine prophylaxis. Iran J Child Neurol 2021;15(2):77-86.
- Shakibaei F, Jelvani D. Effect of adding l -carnitine to risperidone on behavioral, cognitive, social, and physical symptoms in children and adolescents with autism: A randomized double-blinded placebo-controlled clinical trial. Clin Neuropharmacol 2023;4 PubMed
- Moustafa I, Connolly C, Anis M, Mustafa H, Oosthuizen F, Viljoen M. A prospective study to evaluate the efficacy and safety of vitamin E and levocarnitine prophylaxis against doxorubicin-induced cardiotoxicity in adult breast cancer patients. J Oncol Phar PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC