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Dietary supplement

Red Beetroot Juice Extract Powder Ingredients & Drug Interactions

by Materia Organica

Red Beetroot Juice Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Red Beetroot Juice Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Red Beetroot Juice Extract Powder is a dietary supplement by Materia Organica with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Red Beet Root Juice Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Red Beetroot Juice Extract Powder by Materia Organica

Ask about any prescription or over-the-counter medication and we check it for interactions with Red Beetroot Juice Extract Powder by Materia Organica — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Red Beetroot Juice Extract Powder by Materia Organica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient supplement: red beet root juice extract in powder form. There are no inactive fillers or other ingredients listed.

Beet root contains naturally occurring compounds including betanin (the pigment that gives it its deep red color) and nitrates, which are the active components responsible for the supplement's documented effects.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beet's overall clinical evidence instead.

Moderate

Some clinical evidence supports Beet for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced muscle soreness — rated "Possibly Effective" (Natural Medicines).

The data supports beet root extract as possibly effective for athletic performance and for reducing exercise-induced muscle soreness — the kind of soreness you feel a day or two after an intense workout. For other uses, the evidence is either insufficient or points the other way: it's rated possibly ineffective for COPD (chronic obstructive pulmonary disease), and there isn't enough reliable evidence to rate it for blood cholesterol levels (dyslipidemia) or cognitive function.

If you're considering this supplement for athletic recovery, the evidence is promising, but talk with your doctor about whether it fits your overall plan.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and well tolerated by most adults. However, this product is a concentrated supplement, and the safety data for concentrated supplements is thin — so use caution.

Short-term use appears well tolerated overall. The most common side effect is harmless red discoloration of urine and stools; some people have also reported black stools.

In rare cases, particularly at large doses, beet can lower blood calcium (hypocalcemia) or, theoretically, strain the kidneys due to its oxalate content. One case report described a man on blood thinners (antiplatelet drugs) who developed black stools after taking beet pills, though serious bleeding was ruled out.

There isn't enough data on this supplement's safety during lactation to advise either way — talk with your pharmacist or doctor if you're breastfeeding.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any medications processed by the liver enzyme CYP3A4 (a Moderate concern — beet may raise their levels), and any drugs that depend on the CYP1A2 enzyme (a Minor concern — beet may lower their levels). Also flag any blood pressure medications you're taking (Minor concern).

No interactions are documented for any inactive ingredients, since there are none.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Beet root extract is possibly effective for athletic performance and exercise recovery, and it's generally well tolerated as a short-term supplement. If you take any medications — especially those processed by your liver — check them against the medication checker on this page first.

Talk with your pharmacist before starting, particularly if you're on blood pressure drugs or blood thinners.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Beetroot Juice Extract Powder, straight from the product label.

Brand Materia Organica
Barcode (UPC) RBT40058-100g
Net contents 3.5 Ounce(s); 100 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336992
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Beetroot Juice Extract Powder by Materia Organica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
200
UPC/BARCODE
RBT40058-100g
IngredientAmount% DV
Red Beet Root Juice Extract, Powder500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Star-K (Kosher) Certified Star-K Kosher

100% red beetroot juice powder

Seals/Symbols

Star-K (Kosher)

General Statements

Materia Organica primarily sells bulk ingredients to manufacturers and brand owners.

Formulation

Our water extraction and low-heat vacuum drying (wind dried, not spray dried) process preserves the natural nutrients & beneficial qualities of Red Beetroot Juice with improved potency and bioavailability. Water-extracted & water-soluble Better bioavailability and potency Vegetarian/vegan, non-GMO, non-irradiated

No additives, fillers, or other ingredients No petroleum solvents in the extraction No pesticides used growing the beets Vegetarian/vegan, non-GMO, non-irradiated

Vegetarian/vegan, non-GMO, non-irradiated

Product of India 3rd party Lab Tested in USA

Suggested/Recommended/Usage/Directions

Suggested use: Mix 500 mg into water, milk, tea, or a smoothie.

Precautions

For best results consult your physician.

Not recommended for children.

Storage

Store in sealed container in a dry, cool area.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Red Beetroot Juice Extract Powder by Materia Organica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Red Beetroot Juice Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Red Beetroot Juice Extract Powder by Materia Organica

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container200 Amounts shown are per serving.

Red Beet Root Juice Extract, Powder

Interacts with
861 drugs
500 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Red Beet Root Juice Extract, Powder monograph & interactions
Interaction report

Red Beetroot Juice Extract Powder by Materia Organica Drug Interactions

Want to check YOUR meds against Red Beetroot Juice Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Red Beet Root Juice Extract, Powder 861

Individual Drug Interactions

The ingredients in Red Beetroot Juice Extract Powder interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Red Beetroot Juice Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Red Beet Root Juice Extract, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Beetroot Juice Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Red Beet Root Juice Extract, Powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Red Beet Root Juice Extract, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Red Beetroot Juice Extract Powder, from the product label.

Materia Organica

See all Materia Organica products
Name
Materia Organica
City
Quitman
State
TX
ZipCode
75783
Phone Number
800-613-6311
Web Address
www.MateriaOrganica.com
Pharmacist Counseling Corner

Red Beetroot Juice Extract Powder by Materia Organica: Common Questions

Does Red Beetroot Juice Extract Powder by Materia Organica interact with any medications?
Yes. Based on its ingredients, Red Beetroot Juice Extract Powder has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Beetroot Juice Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this turn my pee and poop red?
Yes, red or pink urine and red stools are the most common side effects — but they're completely harmless and just a sign the pigment is passing through your system. Some people report black stools instead. If it bothers you, it typically stops once you stop the supplement.
Does it actually help with muscle soreness after workouts?
The data says it's possibly effective for exercise-induced muscle soreness — the kind you feel a day or two after a hard workout. It's also possibly effective for athletic performance overall. The evidence isn't rock-solid, but it's promising enough to try if you're interested.
Is it safe to take long-term?
Beet as a food is safe eaten regularly, but this is a concentrated supplement and long-term safety data is limited. The safety notes advise caution with concentrated supplements. Stick to short-term use unless your doctor says otherwise, and talk with them about your specific situation.
Can I take this if I'm on blood thinners?
That's a question for your pharmacist or doctor — one case report described someone on blood thinners who developed black stools after taking beet pills. The serious bleeding risk was low in that case, but your doctor needs to know about both your blood thinner and this supplement before you start.
What's in it besides the beet extract?
Just the red beet root juice extract powder — no fillers, binders, or other inactive ingredients are listed.
Is it safe while breastfeeding?
There isn't enough data to know either way. Talk with your pharmacist or doctor for personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Beetroot Juice Extract Powder label
Go deeper

The Full Monographs Behind Red Beetroot Juice Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Red Beetroot Juice Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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