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Dietary supplement

Moringa Leaf Extract Paste Organic Ingredients & Drug Interactions

by Materia Organica

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Moringa Leaf Extract Paste Organic is a dietary supplement by Materia Organica with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moringa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Moringa Leaf Extract Paste Organic by Materia Organica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient moringa leaf extract in powder form. Moringa is a leafy plant traditionally used in some cultures as a nutritional supplement, and this version is certified organic.

There are no other active ingredients, and no inactive fillers or binders listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Moringa product and its label doesn't state a use — see Moringa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold does not establish that moringa leaf is effective for any condition we have data on—including iron-deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, or high cholesterol. The rating for each of these is insufficient reliable evidence, which means the research either hasn't been done or hasn't been robust enough to draw firm conclusions.

If you're considering this product for a specific health goal, talk with your pharmacist or doctor about whether the current evidence supports its use for your situation.

The evidence, ingredient by ingredient Moringa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Moringa leaf powder is generally well tolerated when used in food-like amounts, though high-quality safety studies are limited. The most common side effect is transient diarrhea—in one clinical trial, about 25% of people taking 8 grams daily experienced it.

Rare serious events including allergic reactions and Stevens-Johnson syndrome (a severe skin condition) have been reported. Avoid medicinal amounts, as the root and root bark may stimulate the uterus and lack solid safety data.

If you're breastfeeding and considering moringa for milk production, safety hasn't been well studied, so check with your pharmacist first.

Side effects, ingredient by ingredient Moringa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Moringa.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 870 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications with the search tool on this page if you take any drug metabolized by CYP3A4 enzymes—a very large group that includes many common medications. Also flag levothyroxine (thyroid hormone), P-glycoprotein substrates (like some cancer and heart drugs), antidiabetes medications, and CYP1A2 substrates (including some blood pressure and psychiatric drugs).

No interactions are documented for ingredients we could not check, but this product contains only one checked ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Moringa leaf extract is generally well tolerated as a food supplement, but the evidence for its effectiveness is not yet established in our data, and it interacts with a large number of medications—especially those your liver breaks down and thyroid hormone replacement. If you take any prescription medications, check them against the interaction tool before starting.

Talk with your pharmacist if you're pregnant, breastfeeding, or have diabetes or thyroid disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moringa Leaf Extract Paste Organic, straight from the product label.

Brand Materia Organica
Barcode (UPC) MOR5883-100g
Net contents 3.5 Ounce(s); 100 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 314589
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moringa Leaf Extract Paste Organic by Materia Organica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
200
UPC/BARCODE
MOR5883-100g
IngredientAmount% DV
Moringa500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Certified Organic by CCOF

Water extracted & water-soluble

Product of India

USDA Organic CCOF Certified Organic

Certified USDA NOP Organic

Water-extracted and water-soluble

No additives, fillers, or other ingredients Non-GMO, Vegetarian/Vegan, Non-Irradiated

Non-GMO, Vegetarian/Vegan, Non-Irradiated

Processed in a state-of-the-art facility with FSSC 22000, WHO GMP Certifications. Tested in independent 3rd-party US labs.

No other ingredients added

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic CCOF Certified Organic Star-K (Kosher)

Formula

Star-K (Kosher)

This water extracted, water soluble extract powder is much more bioavailable than ordinary root powders and extract powders. Water extraction preserves Moringa's natural nutrients and beneficial qualities. 100% Moringa Oleifera Leaf

Certified Star-K Kosher

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1/4 teaspoon (500 mg) daily. For best results consult your physician.

Precautions

Keep out of reach of children.

Storage

Store in a sealed container in a dry, cool area.

See for yourself

Moringa Leaf Extract Paste Organic by Materia Organica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Moringa Leaf Extract Paste Organic by Materia Organica

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container200 Amounts shown are per serving.

Moringa

Interacts with
869 drugs
500 mg per serving

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....

Moringa monograph & interactions
Interaction report

Moringa Leaf Extract Paste Organic by Materia Organica Drug Interactions

Want to check YOUR meds against Moringa Leaf Extract Paste Organic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
869Drugs
717 Moderate 152 Minor

Ingredients driving the most interactions

Moringa 869

Each ingredient & the kinds of drugs it affects

For each ingredient in Moringa Leaf Extract Paste Organic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Moringa6 drug types · 869 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Moringa Leaf Extract Paste Organic, from the product label.

Materia Organica

See all Materia Organica products
Name
Materia Organica
Street Address
706C E. Goode Street
City
Quitman
State
TX
ZipCode
75783
Phone Number
800-661-6851
Web Address
www.MateriaOrganica.com
Pharmacist Counseling Corner

Moringa Leaf Extract Paste Organic by Materia Organica: Common Questions

Does Moringa Leaf Extract Paste Organic by Materia Organica interact with any medications?
Yes. Based on its ingredients, Moringa Leaf Extract Paste Organic has a known interaction with 869 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Moringa Leaf Extract Paste Organic contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will moringa help with my blood sugar or diabetes?
Animal research suggests moringa can lower blood glucose, but human research hasn't shown consistent results. The evidence we hold is insufficient to say whether it works for diabetes. Talk with your pharmacist or doctor before using it alongside diabetes medication, since moringa might theoretically add to the glucose-lowering effect.
What's the most common side effect?
Diarrhea is the main side effect reported—it was transient (temporary) and occurred in about 25% of people taking 8 grams daily in a clinical trial. Rare serious allergic reactions, including anaphylaxis, have also been reported.
Can I take this if I'm breastfeeding?
Moringa has been traditionally used to boost milk supply, but safety hasn't been well studied in breastfeeding. There isn't enough data to know if it's safe, so talk with your pharmacist or doctor for personalized advice.
Is there anything other than the moringa leaf in this powder?
No—this is a single-ingredient product with no fillers, binders, or other inactive ingredients listed.
Can I take this with my thyroid medication?
Moringa leaf may interfere with levothyroxine (Synthroid) and potentially reduce how well it works by slowing the conversion of thyroid hormone in your body. If you take thyroid medication, run it through the interaction checker on this page and talk with your pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moringa Leaf Extract Paste Organic is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moringa Leaf Extract Paste Organic label
Go deeper

The Full Monographs Behind Moringa Leaf Extract Paste Organic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Moringa Leaf Extract Paste Organic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Moringa 23 references
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
  3. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  4. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  5. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  6. Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
  7. Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
  8. Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
  9. Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
  10. King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
  11. Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
  12. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  13. Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
  14. Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
  15. Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
  16. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
  17. Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
  18. Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
  19. Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
  20. Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
  21. Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
  22. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  23. Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.

See these in context on the Moringa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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