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Dietary supplement

Red Marine Algae 375 mg Ingredients & Drug Interactions

by Solaray

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Red Marine Algae 375 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement (iodine, minerals), source of plant protein, general wellness.Based on those ingredients, 85 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dulse Seaweed. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Red Marine Algae 375 mg by Solaray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dulse seaweed (375 mg per capsule). Dulse is a red marine algae that's naturally high in potassium and iodine.

The capsule also holds several inactive ingredients — cellulose, silica, magnesium stearate, and rice extract blend — which help hold the supplement together and make it easier to swallow.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Dulse product and its label doesn't state a use — see Dulse's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for dulse on high cholesterol and iodine deficiency is insufficient to rate. The data we hold doesn't establish that this supplement works for those purposes.

If you're considering it for one of those reasons, talk with your pharmacist about what the research actually shows and whether it's the right choice for you.

The evidence, ingredient by ingredient Dulse

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dulse seaweed is generally well tolerated as a food. However, this supplement delivers concentrated amounts of potassium and iodine — much higher than you'd get eating dulse seaweed in normal meals — so caution is needed.

The iodine levels in supplements can be unpredictable, and safety data in humans is limited. If you're breastfeeding, avoid supplement doses of dulse, since excess iodine can pass into breast milk; talk with your doctor for guidance.

No adverse effects have been documented in our data.

Side effects, ingredient by ingredient Dulse

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dulse.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 85 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your pharmacist if you take digoxin, any thyroid medication, antithyroid drugs, amiodarone, ACE inhibitors, ARBs, or potassium-sparing diuretics. These are the drug types most likely to interact with the potassium and iodine in dulse.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you take heart medications (especially digoxin), thyroid medications, amiodarone, or blood pressure drugs that spare potassium, you should check with your pharmacist before taking this product. The risks are theoretical but documented.

This supplement isn't clearly shown to work for the conditions it's marketed for.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Marine Algae 375 mg, straight from the product label.

Brand Solaray
Barcode (UPC) 076280014815
Net contents 100 VegCap(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326110
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Marine Algae 375 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 VegCap(s)
Maximum serving Sizes:
1 VegCap(s)
Servings per container
100
UPC/BARCODE
076280014815
IngredientAmount% DV
Dulse Seaweed375 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Rice extract Blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solaray Est. 1973 A Brighter Way 1973

Formulation

+ Herbal Support

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Non GMO Project Verified nongmoproject.org Lab Verified

General Statements

Since 1973, we've scoured the globe for the highest quality ingredients, connection you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.

100% PCR Bottles

Precautions

Warning: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product. Do not use if you have hyperthyroidism. Not recommended for excessive or long-term use.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 1 vegcap daily with a meal or glass of water.

Storage

Store in a cool, dry place.

Formula

Discussion: Red marine algae, also known as dulse, is a type of seaweed that has been used as a food staple for thousands of years. Often referred to as a sea vegetable, research suggests that the sulfated polysaccharides found in red marine algae may provide nutritive support for immune health.

True Herbs

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Red Marine Algae 375 mg by Solaray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Red Marine Algae 375 mg by Solaray

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 VegCap(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Dulse Seaweed

Interacts with
85 drugs
375 mg per serving

Dulse is a red seaweed eaten as a food in many coastal cultures and is a natural source of iodine, potassium, protein, and antioxidant compounds. As a...

Dulse Seaweed monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Rice extract Blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Red Marine Algae 375 mg by Solaray Drug Interactions

Want to check YOUR meds against Red Marine Algae 375 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
85Drugs
23 Moderate 62 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Marine Algae 375 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dulse Seaweed7 drug types · 85 drugs

Amiodarine (Cordarone)

Theoretically, combining dulse with amiodarone might cause excessively high iodine levels.
Dulse is rich in iodine, and amiodarone contains 37.3% iodine and can increase iodine levels.

Likelihood Possible Evidence D
Antithyroid Drugs

Theoretically, due to its iodine content, dulse might alter the effects of antithyroid drugs.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, dulse might increase the risk of hyperkalemia when taken with digoxin.
Dulse is rich in potassium, and digoxin can increase potassium levels in the blood. This interaction has not been demonstrated in humans.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, due to its iodine content, dulse might alter the effects of thyroid hormone.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Although dulse has been associated with a statistically significant increase in thyroid stimulating hormone (TSH) levels in clinical research, clinically significant increases have not been documented.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, dulse might increase the risk of hyperkalemia when taken with ACEIs.
Dulse is rich in potassium. ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide larger amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of ACE. However, these effects have not been demonstrated in humans.

Likelihood Possible Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, dulse might increase the risk of hyperkalemia when taken with ARBs.
Dulse is rich in potassium. ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide higher amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of angiotensin converting enzyme (ACE). However, these effects have not been demonstrated in humans.

Likelihood Possible Evidence D
Potassium-Sparing Diuretics

Theoretically, dulse might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dulse is rich in potassium, and potassium-sparing diuretics can increase potassium levels in the blood. This interaction has not been shown in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Red Marine Algae 375 mg, from the product label.

Solaray

See all Solaray products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Red Marine Algae 375 mg by Solaray: Common Questions

Does Red Marine Algae 375 mg by Solaray interact with any medications?
Yes. Based on its ingredients, Red Marine Algae 375 mg has a known interaction with 85 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Marine Algae 375 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is in this supplement?
It's dulse seaweed — a red marine algae — at 375 mg per capsule, plus inactive ingredients like cellulose and silica that help hold the capsule together. There's only one active ingredient.
Does dulse actually work for high cholesterol?
The evidence isn't strong enough to say. We don't have reliable data showing dulse lowers cholesterol, so we can't rate it for that use.
Is this safe if I'm pregnant?
The data on file doesn't tell us either way. Talk with your doctor or pharmacist before taking it — they can give you personalized advice based on your health.
What if I'm breastfeeding?
Avoid supplement doses of dulse while breastfeeding. The concentrated iodine in supplements can pass into breast milk. Check with your doctor before taking this product.
Can I take this with my blood pressure medication?
It depends which one. If you're on an ACE inhibitor, ARB, or potassium-sparing diuretic, there's a theoretical risk because dulse is high in potassium. Run your exact medication through the checker on this page or ask your pharmacist.
What are the side effects?
No adverse effects have been documented in the data we hold, but keep in mind that as a supplement high in potassium and iodine, it should be used cautiously — especially if you have kidney problems or thyroid disease.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Red Marine Algae 375 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Marine Algae 375 mg label
Go deeper

The Full Monographs Behind Red Marine Algae 375 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Red Marine Algae 375 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dulse 5 references
  1. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  2. Allsopp P, Crowe W, Bahar B, et al. The effect of consuming Palmaria palmata-enriched bread on inflammatory markers, antioxidant status, lipid profile and thyroid function in a randomised placebo-controlled intervention trial in healthy adults. Eur J Nutr PubMed
  3. McGrath BM, Harmon JP, Bishop G. Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report. J Med Case Rep. 2010;4:301. PubMed
  4. Furuta T, Miyabe Y, Yasui H, Kinoshita Y, Kishimura H. Angiotensin I converting enzyme inhibitory peptides derived from phycobiliproteins of dulse Palmaria palmata. Mar Drugs. 2016;14(2):32. PubMed
  5. Takase T, Nakamura A, Miyoshi H, et al. Effects of Palmaria palmata on lipid metabolism and glycemic control in participants with hypercholesterolemia in a randomized double-blind placebo-controlled trial. Phytother Res. 2020.

See these in context on the Dulse monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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