Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Reduced Glutathione Complex 50 mg Orange Flavored Ingredients & Drug Interactions

by Source Naturals

Lozenge Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Reduced Glutathione Complex 50 mg Orange Flavored is a dietary supplement by Source Naturals with 3 active ingredients. Its ingredients are commonly taken for correcting molybdenum deficiency, supporting enzyme function, general nutritional supplementation.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This lozenge contains three active ingredients: L-Glutathione (the primary component at 50 mg per dose), Molybdenum, and Riboflavin. L-Glutathione is an amino acid compound your body makes naturally and uses in many cellular processes.

Molybdenum is a trace mineral, and Riboflavin (also called vitamin B2) is a B vitamin that helps turn food into energy. The product also contains inactive ingredients — sorbitol and mannitol (sweeteners), natural orange flavor, and magnesium stearate (a flow agent).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: liver detoxification and free radical scavenging.
  • We looked for evidence on: Liver disease, Antioxidant support, Glutathione deficiency, Oxidative stress.
  • The closest evidence on file: Molybdenum is rated "Insufficient Reliable Evidence To Rate" for Liver disease (Natural Medicines).

We don't have effectiveness data on file for L-Glutathione or for this product as a whole in our database. For Molybdenum, the evidence shows it's likely effective for preventing molybdenum deficiency — but that deficiency is extremely rare.

For other uses like acne, anemia, asthma, osteoporosis, and cancer prevention, the evidence is too limited to rate. Riboflavin has no effectiveness ratings listed in our data for any condition.

The evidence, ingredient by ingredient Molybdenum Riboflavin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is very safe and excess amounts are shed in your urine; it's generally well tolerated, though some people report dose-related nausea or bright yellow urine at higher doses. Molybdenum from food and prenatal vitamins is fine, but high-dose supplements may cause problems and are rarely necessary — one case report documented serious effects (psychosis, seizures, brain damage) from very high supplemental doses, though this is extremely rare.

Riboflavin is considered likely safe during pregnancy and breastfeeding at recommended doses; check with your provider before using high-dose supplements. We have no pregnancy or breastfeeding safety data on file for L-Glutathione or Molybdenum.

Side effects, ingredient by ingredient Molybdenum Riboflavin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product if you take tetracycline antibiotics (doxycycline, minocycline, tetracycline, and others in that class) — a Moderate interaction with riboflavin may reduce how well they work. No interactions are documented for the ingredients we could check with any other medication types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take tetracycline antibiotics, check this product with your pharmacist first — Moderate interaction potential with riboflavin. If you don't take that class of antibiotic, the ingredients are generally well tolerated at normal doses.

Molybdenum and Riboflavin are safe in these amounts; L-Glutathione's effects we can't verify from our data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reduced Glutathione Complex 50 mg Orange Flavored, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078013051
Net contents 100 Lozenge(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 275446
Product type Other Combinations
Supplement form Lozenge
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Lozenge(s)
Maximum serving Sizes:
1 Lozenge(s)
Servings per container
100
UPC/BARCODE
021078013051
IngredientAmount% DV
L-Glutathione50 mg--
Total Carbohydrate1 Gram(s)1%
Molybdenum120 mcg160%
Riboflavin1.6 mg94%

Other ingredients: Sorbitol, Mannitol, natural Orange flavor, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Reduced Glutathione Complex 50 mg

Reduced Glutathione Complex contains glutathione (GSH), a key element of the liver's detoxifying process, and also the precursor for glutathione peroxidase, a major free radical scavenging enzyme. Recent scientific research indicates that molybdenum, a trace mineral that activates the enzymes aldehyde oxidase and sulfite oxidase, may provide necessary nutritional support for chemically sensitive individuals. Coenzymated vitamin B-2 (riboflavin) is the precursor for FAD, a coenzyme that recycles used GSH.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 lozenge 1 to 3 times daily. For best results, allow to dissolve in the mouth before swallowing.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation

Suitable for vegetarians.

Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright SOURCE NATURALS, INC.

See for yourself

Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Lozenge(s) Dosage formLozenge Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutathione

50 mg per serving

Molybdenum

No known
interactions
120 mcg per serving Form: Molybdenum Chelate

Molybdenum is an essential trace mineral your body needs in tiny amounts to help certain enzymes work. Most people get enough from a normal diet, so s...

Molybdenum monograph & interactions

Riboflavin

Interacts with
20 drugs
1.6 mg per serving Form: Flavin Mononucleotide

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Other (inactive) ingredients: Sorbitol, Mannitol, Natural Orange flavor, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals Drug Interactions

Want to check YOUR meds against Reduced Glutathione Complex 50 mg Orange Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Reduced Glutathione Complex 50 mg Orange Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Reduced Glutathione Complex 50 mg Orange Flavored, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals: Common Questions

Does Reduced Glutathione Complex 50 mg Orange Flavored by Source Naturals interact with any medications?
Yes. Based on its ingredients, Reduced Glutathione Complex 50 mg Orange Flavored has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reduced Glutathione Complex 50 mg Orange Flavored contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for boosting glutathione levels?
We don't have effectiveness data on file for L-Glutathione in our database, so I can't tell you whether this product raises your glutathione. Talk with your pharmacist or doctor about whether supplementation makes sense for you.
Is molybdenum safe at the dose in this product?
Yes — the amount here is well below the safe upper limit of 2 mg per day, and molybdenum is generally well tolerated at normal doses. High-dose supplements are rarely necessary and should only be used under medical advice.
Can I take this while pregnant or breastfeeding?
Riboflavin is likely safe during pregnancy and breastfeeding at recommended amounts, but ask your provider before using any high-dose supplements. We don't have safety data on file for L-Glutathione or Molybdenum in pregnancy and breastfeeding, so check with your doctor for personalized advice.
What side effects might I get?
Riboflavin can cause dose-related nausea and bright yellow urine at higher doses — these effects are usually harmless. Diarrhea is rare. Molybdenum is generally well tolerated in normal amounts.
Does this have fillers or just the active ingredients?
This lozenge contains sorbitol and mannitol (sweeteners), natural orange flavor, and magnesium stearate — these are inactive ingredients that help make the lozenge work and taste good.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reduced Glutathione Complex 50 mg Orange Flavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reduced Glutathione Complex 50 mg Orange Flavored label
Sources

Sources & How We Checked

Reduced Glutathione Complex 50 mg Orange Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Molybdenum 8 references
  1. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Rajagopalan KV. Molybdenum: an essential trace element in human nutrition. Annu Rev Nutr 1988;8:401-27. PubMed
  4. Selden AI, Berg NP, Soderbergh A, Bergstrom BE. Occupational molybdenum exposure and a gouty electrician. Occup Med (Lond) 2005;55:145-8. PubMed
  5. Al-Saleh E, Nandakumaran M, Al-Shammari M, Al-Harouny A. Maternal-fetal status of copper, iron, molybdenum, selenium and zinc in patients with gestational diabetes. J Matern Fetal Neonatal Med 2004;16:15-21. PubMed
  6. Koster R, Vieluf D, Kiehn M, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 2000;356:1895-7. PubMed
  7. Vyskocil A, Viau C. Assessment of molybdenum toxicity in humans. J Appl Toxicol 1999;19:185-92. DOI
  8. Momcilovic, B. A case report of acute human molybdenum toxicity from a dietary molybdenum supplement--a new member of the "Lucor metallicum" family. Arh.Hig.Rada Toksikol. 1999;50(3):289-297. DOI

See these in context on the Molybdenum monograph →

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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