Major interaction on record — check this product against your medications before combining. Based on 9 of 10 ingredients. Check your meds →
Dietary supplement

Resp-X Ingredients & Drug Interactions

by NeoLife Nutritionals

Resp-X label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Resp-X against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Resp-X is a dietary supplement by NeoLife Nutritionals with 10 active ingredients. Its ingredients are commonly taken for nerve pain (neuropathy), muscle and joint pain (arthritis), back pain.Based on those ingredients, 2,197 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Slippery Elm, Alfalfa, Fenugreek. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Resp-X by NeoLife Nutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with Resp-X by NeoLife Nutritionals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Resp-X by NeoLife Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Herbal Proprietary Blend” is a proprietary blend — the label gives one combined amount (570 mg) without saying how much of each component you get.

Resp-X contains 10 active ingredients: cayenne, yerba santa, thyme, fenugreek, bee pollen, horseradish, slippery elm, alfalfa, and hyssop, plus a proprietary herbal blend. The product also contains inactive ingredients including stearic acid, microcrystalline cellulose, gum arabic, sodium croscarmellose, silicon dioxide, magnesium stearate, hydroxypropyl methylcellulose, and glycerin, which serve as binders, fillers, and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: upper respiratory tract wellness and sinus comfort.
  • We looked for evidence on: Allergic rhinitis (hay fever), Bronchitis, Common cold, Cough, Laryngitis, Nonallergic rhinitis — and 4 related terms.
  • The strongest evidence on file: Capsicum is rated "Possibly Effective" for Nonallergic rhinitis (Natural Medicines).
  • Also on file: Bee Pollen is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever).
  • Also on file: Hyssop is rated "Insufficient Reliable Evidence To Rate" for Cough.

The evidence for Resp-X's ingredients is limited. Cayenne shows likely effectiveness for postherpetic neuralgia (nerve pain after shingles) and diabetic neuropathy (nerve damage from diabetes), and possibly effective for cluster headache, back pain, and nausea after surgery.

Fenugreek is possibly effective for sexual dysfunction and diabetes. Most other ingredients—yerba santa, thyme, bee pollen, horseradish, slippery elm, alfalfa, and hyssop—lack sufficient reliable evidence to rate their effectiveness for the conditions they're traditionally used for.

The evidence, ingredient by ingredient Capsicum Yerba Santa Thyme Fenugreek Bee Pollen Horseradish Slippery Elm Alfalfa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cayenne is generally well tolerated in food amounts or supplement doses up to 200 mg daily, though it commonly causes burning and irritation. Orally, it may cause belching, bloating, burning, diarrhea, gas, headache, nausea, skin flushing, and sweating.

Thyme is well tolerated as food or in tea; the concentrated essential oil can be toxic if swallowed. Fenugreek is generally well tolerated but may cause abdominal pain, bloating, diarrhea, gas, or nausea; serious allergic reactions including bronchospasm and shock are rare.

Bee pollen is well tolerated in most people but can trigger severe allergic reactions in those with pollen allergies. Horseradish in food amounts is safe, but large amounts can cause gastrointestinal upset and rarely vasovagal fainting.

Slippery elm is generally well tolerated for short-term use. Alfalfa in small food amounts is considered safe, but supplements carry real risks for some people.

Yerba santa, hyssop, and molasses have limited human safety data.

Side effects, ingredient by ingredient Capsicum Yerba Santa Thyme Fenugreek Bee Pollen Horseradish Slippery Elm Alfalfa

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 8 of the 9 matched ingredients can interact with medications — Alfalfa, Bee Pollen, Horseradish, Yerba Santa, Fenugreek, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 2,198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Resp-X, double-check the following medication types with your doctor or pharmacist: warfarin and other blood thinners (Major risk from alfalfa), then blood sugar medications, theophylline, birth control and estrogen therapy, blood pressure drugs, anticholinergic and cholinergic medications, ciprofloxacin, phenytoin, sildenafil, thyroid hormone, lithium, immunosuppressants, and any oral drugs you depend on for absorption. Slippery elm may slow how your body takes in oral medications generally.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Resp-X is a multi-ingredient herbal supplement with limited evidence for most of its intended uses — cayenne and fenugreek have the strongest data for specific conditions like neuropathy and diabetes. The real concern is its interactions with common medications, especially blood thinners, diabetes drugs, and several others: if you take any prescription medication, you need to check it against this product before starting.

Talk with your own doctor or pharmacist to see if Resp-X is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Resp-X, straight from the product label.

Brand NeoLife Nutritionals
Barcode (UPC) 3652s
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303289
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Resp-X by NeoLife Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
3652s
IngredientAmount% DV
Cayenne0 NP--
Yerba Santa0 NP--
Thyme0 NP--
Fenugreek0 NP--
Bee Pollen0 NP--
Herbal Proprietary Blend570 mg--
Molasses0 NP--
Horseradish0 NP--
Slippery Elm0 NP--
Alfalfa0 NP--
Hyssop0 NP--

Other ingredients: Stearic Acid, Microcrystalline Cellulose, Gum Arabic, Sodium Croscarmellose, Silicon Dioxide, Magnesium Stearate, Hydroxypropyl Methylcellulose, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

NeoLife's Resp-X natural herbal blend is a unique formulation containing the finest ingredients for the purpose of maximizing co-related benefits for upper respiratory tract wellness. Includes horseradish root to support normal airflow in the sinuses and lungs. Hyssop and thyme promote clear, open airways. Resp-X uses a synergistic Herbal Blend derived from ancient herbal knowledge and leading edge science to support sinus decongestion and free, comfortable breathing.

Certified kosher

Precautions

To be used during pregnancy and lactation only after checking with a physician/medical doctor.

Keep out of reach of children.

Packaged with safety seal.

Contains soy and wheat.

Storage

Store in a cool, dry place, away from direct sunlight.

Formulation

Based in nature

To soothe your sinuses for comfortable breathing

Based in nature. Backed by science.

Made in U.S.A.

NeoLife scientific advisory board

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 1 tablet as needed.

General Statements

Not sold in retail stores.

Available exclusively from NeoLife Promoters

Leading edge nutrition since 1958.

Seals/Symbols

SAB Scientific Advisory Board

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Resp-X by NeoLife Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Resp-X label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Resp-X by NeoLife Nutritionals

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Herbal Proprietary Blend

570 mg per serving

Other (inactive) ingredients: Stearic Acid, Microcrystalline Cellulose, Gum Arabic, Sodium Croscarmellose, Silicon Dioxide, Magnesium Stearate, Hydroxypropyl Methylcellulose, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Resp-X by NeoLife Nutritionals Drug Interactions

Want to check YOUR meds against Resp-X?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,197Drugs
2 Major 2,191 Moderate 4 Minor

Ingredients driving the most interactions

Slippery Elm 2,022
Alfalfa 583
Fenugreek 389
Thyme 379
Cayenne 239

Individual Drug Interactions

The ingredients in Resp-X interact with 2,197 drugs. Click any drug to see the details.

8 of the 10 ingredients in Resp-X interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Alfalfa Fenugreek Thyme Cayenne Horseradish Bee Pollen Yerba Santa

Each ingredient & the kinds of drugs it affects

For each ingredient in Resp-X with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm full monograph & interactions

Alfalfa6 drug types · 583 drugs

Warfarin (Coumadin)

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.

Likelihood Possible Evidence D
Alfalfa full monograph & interactions

Fenugreek9 drug types · 389 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.

Likelihood Probable Evidence B
Clopidogrel (Plavix)

Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.

Likelihood Possible Evidence D
Metoprolol (Toprol)

Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.

Likelihood Possible Evidence C
Fenugreek full monograph & interactions

Thyme4 drug types · 379 drugs

Anticholinergic Drugs

Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, thyme leaf extract might have additive effects with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that thyme leaf extract has antiplatelet effects. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of cholinergic drugs and thyme essential oil might cause additive cholinergic effects.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, thyme might competitively inhibit the effects of estrogen replacement therapy.
In vitro research shows that thyme has estrogen receptor-binding activity and phytoestrogen content. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Thyme full monograph & interactions

Cayenne6 drug types · 239 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro research shows that capsicum might increase the effects of antiplatelet drugs. Also, population research shows that capsicum is associated with an increased risk of self-reported bleeding in patients taking warfarin. However, clinical research shows that taking a single dose of capsaicin (Asian Herbex Ltd.), the active ingredient in capsicum, 400-800 mcg orally in combination with aspirin 500 mg does not decrease platelet aggregation when compared with taking aspirin 500 mg alone. Also, there was no notable effect on measures of platelet aggregation with capsaicin. It is unclear whether capsaicin must be used in more than a single dose to affect platelet aggregation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that consuming capsicum 5 grams along with a glucose drink attenuates the rise in plasma glucose after 30 minutes by 21%, decreases the 2-hour postprandial area under the curve of plasma glucose by 11%, and increases the 2-hour postprandial area under the curve of plasma insulin by 58% in healthy individuals when compared with placebo. Other clinical research shows that taking capsicum 5 mg daily for 28 days significantly reduces postprandial blood glucose and insulin levels, but not fasting blood glucose and insulin levels, in patients with gestational diabetes.

Likelihood Possible Evidence B
Aspirin

Theoretically, taking capsicum with aspirin might reduce the bioavailability of aspirin.
Animal research shows that acute or chronic intake of capsicum pepper reduces oral aspirin bioavailability. This has not been shown in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, taking capsicum with theophylline might increase the levels and adverse effects of theophylline.
In animal research, oral administration of capsicum reduced excretion of theophylline. However, capsicum does not seem to affect the pharmacokinetics of theophylline when administered intravenously.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.
There is one case report of a topically applied capsaicin cream contributing to the cough reflex in a patient using an ACEI. However, it is unclear if this interaction is clinically significant.

Likelihood Unlikely Evidence D
Ciprofloxacin (Cipro)

Theoretically, taking capsicum with ciprofloxacin might increase levels and adverse effects of ciprofloxacin.
Animal research shows that concomitant use of capsaicin, the active constituent of capsicum, and ciprofloxacin increases the bioavailability of ciprofloxacin by up to 70%.

Likelihood Possible Evidence D
Cayenne full monograph & interactions

Horseradish1 drug type · 16 drugs

Thyroid Hormone

Theoretically, horseradish might interfere with the effects of thyroid hormone.
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function.

Likelihood Possible Evidence D
Horseradish full monograph & interactions

Bee Pollen1 drug type · 2 drugs

Warfarin (Coumadin)

There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.

Likelihood Possible Evidence D
Bee Pollen full monograph & interactions

Yerba Santa1 drug type · 1 drug

Lithium

Yerba santa is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, yerba santa might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yerba Santa full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Resp-X, from the product label.

NeoLife Nutritionals

See all NeoLife Nutritionals products
Name
NeoLife International, LLC
City
Santa Clara
State
CA
ZipCode
95054
Web Address
NeoLife.com
Pharmacist Counseling Corner

Resp-X by NeoLife Nutritionals: Common Questions

Does Resp-X by NeoLife Nutritionals interact with any medications?
Yes. Based on its ingredients, Resp-X has a known interaction with 2,197 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Resp-X contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Resp-X actually work for respiratory issues?
The evidence is limited. Cayenne and thyme are traditionally used for respiratory health, but the data we hold rates most of the respiratory claims as having insufficient reliable evidence. Cayenne does have strong evidence for certain types of nerve pain, so if you're considering this for that, it may be worth a conversation with your doctor.
Can I take Resp-X if I'm on warfarin (Coumadin)?
No — not without checking with your doctor first. Alfalfa in this product is rated Major risk with warfarin because its vitamin K can block the drug's blood-thinning effect. Several other ingredients also interact with warfarin. Talk to your pharmacist or doctor before adding this to your routine.
What are the most common side effects?
Cayenne commonly causes burning, bloating, gas, nausea, and diarrhea. Fenugreek may cause similar digestive upset plus abdominal pain. Horseradish and thyme can irritate the digestive tract in larger amounts. Most people tolerate food amounts of these herbs fine, but supplement doses are a different story.
Is Resp-X safe if I'm pregnant or breastfeeding?
It depends on the ingredient. Cayenne and thyme are likely safe, but fenugreek is likely unsafe in pregnancy and alfalfa is possibly unsafe in both pregnancy and breastfeeding. Yerba santa, hyssop, and bee pollen have not been well studied. Talk with your doctor or pharmacist before using this product if you're pregnant or nursing.
Does slippery elm in Resp-X affect how my other medications work?
Yes — theoretically. Slippery elm contains mucilage that may slow down how your body absorbs oral medications. If you take other drugs regularly, especially those you depend on for timing or absorption, check with your pharmacist before combining them with Resp-X.
Can I take Resp-X with my diabetes medication?
Check with your doctor first. Both cayenne and fenugreek can lower blood sugar, so taken with diabetes drugs, they could increase the risk of low blood sugar (hypoglycemia). Your doctor may need to watch your levels more closely or adjust your dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Resp-X label
Go deeper

The Full Monographs Behind Resp-X’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Capsicum

Interacts with 239 drugs

Capsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain. Topical capsaicin products are supported by reasonable evid...

Read the full Capsicum monograph → Herb & supplement monograph

Yerba Santa

Interacts with 1 drug

Yerba Santa is an aromatic shrub from the western United States and Mexico that has long been used in folk medicine for coughs, congestion, and other respiratory complaints. Modern scientifi...

Read the full Yerba Santa monograph → Herb & supplement monograph

Thyme

Interacts with 379 drugs

Thyme is a common kitchen herb that has long been used for coughs, sore throats, and digestive complaints. It is generally safe in the amounts found in food, and some cough products that com...

Read the full Thyme monograph → Herb & supplement monograph

Fenugreek

Interacts with 389 drugs

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...

Read the full Fenugreek monograph → Herb & supplement monograph

Bee Pollen

Interacts with 2 drugs

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...

Read the full Bee Pollen monograph → Herb & supplement monograph

Horseradish

Interacts with 16 drugs

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited, and while culinary amounts are generall...

Read the full Horseradish monograph → Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Alfalfa

Interacts with 583 drugs

Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...

Read the full Alfalfa monograph → Herb & supplement monograph

Hyssop

Hyssop is a Mediterranean mint-family herb traditionally used for coughs, colds, and digestive complaints, but solid human evidence for these uses is lacking. The dried herb in tea is genera...

Read the full Hyssop monograph →
Sources

Sources & How We Checked

Resp-X's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 194 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Capsicum 89 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Cooper RL, Cooper MM. Red pepper-induced dermatitis in breast-fed infants. Dermatol 1996;93:61-2. PubMed
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Bee Pollen 15 references
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Horseradish 6 references
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Slippery Elm 3 references
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Alfalfa 32 references
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Hyssop 1 reference
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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