Rosehips Alcohol Free Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Rosehips Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Rosehips Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for joint pain and osteoarthritis, colds and flu, source of vitamin c.Based on those ingredients, 213 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rose Hip Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Rosehips Alcohol Free by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Rosehips Alcohol Free by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Rosehips Alcohol Free by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: rose hip fruit extract (dry form). Rose hip is the fruit of the wild rose plant, traditionally used for joint and digestive support.
The liquid also contains two inactive ingredients—glycerin and water—which help deliver the extract.
Does it work?
Moderate evidence
The evidence suggests rose hip may help with postoperative pain (pain after surgery) and osteoarthritis symptoms—both rated as possibly effective based on available research. We don't have enough reliable evidence to rate its use for lowering cholesterol (hyperlipidemia).
If you're considering it for one of these reasons, talk with your healthcare provider about whether the current evidence fits your situation.
How safe is it?
Well-documented data
Rose hip from common species like Rosa canina and Rosa damascena is generally well tolerated as a food and as a supplement dose. The most common side effects are mild: flatulence and loose stools.
Rarely, vertigo and headache have been reported. Gastrointestinal upset—cramping, acid reflux, nausea, diarrhea—can occur, though in clinical trials these happened just as often in people taking placebo.
Because concentrated supplement safety is less well studied than whole-food amounts, use caution and talk with your doctor before starting if you have any health concerns. We have no pregnancy or breastfeeding safety data on file for rose hip; if you're pregnant or nursing, discuss this supplement with your OB or pharmacist before use.
Meds to double-check
Moderate interaction found
Before taking this product, double-check if you're on estrogens (birth control, hormone replacement therapy), blood thinners or antiplatelet drugs (warfarin, aspirin), lithium, chemotherapy drugs (alkylating agents or antitumor antibiotics), or aluminum-containing antacids. The interaction with estrogens is the most serious.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Rose hip may help with postoperative pain or osteoarthritis, but it's not a slam-dunk for any condition. The real question is whether you're on a hormone, blood thinner, lithium, or chemotherapy drug—those are the big interactions to watch.
Talk to us or your doctor before starting, especially if you take any prescription medication.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Rosehips Alcohol Free, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253645043 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 332053 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Rosehips Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rose Hip Fruit Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Scan this QR code to get more info or reorder
Formula
Rosa canina
Formulation
Only natural ingredients Identity and purity is laboratory verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
C2H5OH Alcohol free
Made in USA, Hawaii
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Rosehips Alcohol Free by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Rosehips Alcohol Free by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Rose Hip Fruit Extract, Dry
Interacts with213 drugs
Rose hip is the vitamin C–rich fruit of the wild rose, used traditionally for colds and joint pain. A standardized rose hip powder has some research s...
Rose Hip Fruit Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Rosehips Alcohol Free by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Hawaii Pharm's Rosehips Alcohol Free contains rose hip fruit extract, which interacts with a number of medications.
The most serious concern is with estrogens—including birth control pills and hormone replacement therapy. Rose hip's vitamin C content may raise estrogen blood levels by up to 55%, which could reduce contraceptive or hormone therapy effectiveness or cause unwanted hormone effects.
Read the full breakdown — every affected drug type, severity by severity
Blood thinners and antiplatelet drugs (like warfarin and aspirin) also warrant caution. Rose hip may theoretically reduce how well these drugs work by promoting blood clotting; however, the vitamin C amount in rose hip is likely too low to cause major problems with aspirin or warfarin specifically.
If you take any blood thinner, check with us before starting.
Additionally, rose hip may affect lithium (used for mood disorders) by reducing how your kidneys clear it, potentially raising blood levels to unsafe ranges. It may also interfere with certain chemotherapy drugs—both alkylating agents and antitumor antibiotics—by counteracting their free-radical-generating action.
Finally, rose hip's vitamin C may increase how much aluminum your body absorbs if you take aluminum-containing antacids or supplements.
Although rose hip contains only one active ingredient, these interactions span 213 individual medications. Use the medication checker below to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Rosehips Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Rosehips Alcohol Free interact with 213 drugs. Click any drug to see the details.
1 of the 1 ingredient in Rosehips Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Rose Hip Fruit Extract, Dry
AbciximabReoPro
How Abciximab interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Acetylsalicylic Acid interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Alginic Acid, Aluminum Hydroxide interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of alkylating agents but might also reduce the oxidative damage caused by certain alkylating agents.
Read the full Rose Hip Fruit Extract, Dry + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin +1 Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin +1 Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAluminum Moderate
Interaction Summary
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Read the full Rose Hip Fruit Extract, Dry + Aluminum, Magnesium Hydroxide (otc Drug) interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin +1 Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Rosehips Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rose Hip Fruit Extract, DryAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip Fruit Extract, Dry + Aspirin, Butalbital, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Rosehips Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rose Hip Fruit Extract, Dry
Alkylating Agents
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of alkylating agents but might also reduce the oxidative damage caused by certain alkylating agents.
Rose hip contains vitamin C. The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. Further, some animal research suggests that the antioxidant effects of rose hip might attenuate cyclophosphamide-induced testicular toxicity. More evidence is needed to determine what effect, if any, antioxidants found in rose hip, such as vitamin C, have on the effectiveness and adverse effects of chemotherapy.
Aluminum
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Rose hip contains vitamin C. Theoretically, vitamin C increases the absorption of aluminum. Concomitant use might increase aluminum absorption, but the clinical significance of this is unknown. Administer rose hip two hours before or four hours after antacids.
Anticoagulant/Antiplatelet Drugs
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that a constituent of rose hip, rugosin E, can induce platelet aggregation. This has not been shown in humans. Theoretically, concomitant use of rose hip might reduce the effectiveness of antiplatelet or anticoagulant drugs.
Antitumor Antibiotics
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of antitumor antibiotics.
Rose hip contains the antioxidant vitamin C. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.
Estrogens
Theoretically, rose hip might increase blood levels of estrogens.
Rose hip contains vitamin C. Increases in plasma estrogen levels of up to 55% have occured under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.
Lithium
Theoretically, rose hip might increase blood levels of lithium.
Rose hip is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, rose hip might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Aspirin
Theoretically, rose hip might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Rose hip contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of rose hip is typically about 500 mg per 100 grams. Thus, a clinically significant interaction between rose hip and aspirin is unlikely.
Warfarin (Coumadin)
Theoretically, rose hip might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Rose hip contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of rose hip is typically about 500 mg per 100 grams. Thus, a clinically significant interaction between rose hip and warfarin is unlikely.
Brand information
Manufacturer and brand details for Rosehips Alcohol Free, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Rosehips Alcohol Free by Hawaii Pharm: Common Questions
Does Rosehips Alcohol Free by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on birth control?
What are the most common side effects?
Does rose hip actually work for arthritis?
Is it safe if I'm on a blood thinner like warfarin?
Can I take this while pregnant or nursing?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Rosehips Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Rosehips Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Rosehips Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rose Hip 24 references
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
- Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
- Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
- Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
- Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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