Drug & supplement interaction

Rose Hip + Alginic Acid, Aluminum Hydroxide

Alginic Acid, Aluminum Hydroxide brand name: Rafton.

Moderate Interaction
The bottom line Moderate

Rose Hip has a moderate interaction with Alginic Acid, Aluminum Hydroxide. Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Rose Hip and Alginic Acid, Aluminum Hydroxide

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ALUMINUM

Why this applies to Alginic Acid, Aluminum Hydroxide

Alginic Acid, Aluminum Hydroxide falls under ALUMINUM — the group Rose Hip interacts with.

Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Rose hip contains vitamin C. Theoretically, vitamin C increases the absorption of aluminum. Concomitant use might increase aluminum absorption, but the clinical significance of this is unknown. Administer rose hip two hours before or four hours after antacids.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version. Your Rafton contains aluminum hydroxide, and rose hip is naturally loaded with vitamin C. On paper, that vitamin C could help your body soak up a little more aluminum than it normally would from the antacid. This idea comes from how the two interact in theory, not from real-world studies showing harm, so I don't want you to worry.

For most people taking an occasional antacid, this is unlikely to cause trouble. The bigger caution is if you have kidney problems, since aluminum can build up when kidneys can't clear it well. An easy fix is timing: take rose hip about two hours before or four hours after your Rafton. Please run it by your pharmacist or doctor first.

References
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Rose Hip Also Interacts With Other Medications

Rose Hip has 212 moderate known drug interactions in our database — the Alginic Acid, Aluminum Hydroxide one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Rose Hip

Covers the 2,830 medications we’ve checked against Rose Hip. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Alginic Acid, Aluminum Hydroxide

This page covers Rose Hip only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alginic Acid, Aluminum Hydroxide page lists 35 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Calcium (moderate), Cinchona (moderate), Coffee Charcoal (moderate) and European Mandrake (moderate).

By severity: 1 major · 14 moderate · 20 minor.

From our pharmacist’s overview on the Alginic Acid, Aluminum Hydroxide page

“Rafton (alginic acid with aluminum hydroxide) treats heartburn, and the people who take it are often the same people reaching for fiber supplements, vitamins, or a charcoal detox product, which is exactly where this list turns serious. Of the 35 supplement and herbal ingredients on file, one is rated major: activated charcoal, which ca…”

Reviewed by 2 · Jul 18, 2026

Open the Alginic Acid, Aluminum Hydroxide interaction page

One more smart check

Taking Rose Hip as Part of a Dietary Supplement Product? Check It for Interactions

We hold 273 real supplement products containing Rose Hip, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rose Hip. Your product may carry other ingredients that interact with Alginic Acid, Aluminum Hydroxide too, on top of Rose Hip — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rose Hip and Alginic Acid, Aluminum Hydroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rose Hip
Top half

#379 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Alginic Acid, Aluminum Hydroxide
Top 5%

#99 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Rose Hip

What is Rose Hip?

Rose Hip
  • Joint pain and osteoarthritis
  • Colds and flu
  • Source of vitamin C
  • Digestive complaints
  • Anti-inflammatory support

Rose hip is the vitamin C–rich fruit of the wild rose, used traditionally for colds and joint pain. A standardized rose hip powder has some research support for easing osteoarthritis symptoms, but evidence for most other uses is limited. It is generally well tolerated as a food, but talk with your pharmacist or doctor before using it as a supplement.

Read the full Rose Hip monograph & all interactions
Keep checking

Other Drugs & Rose Hip

Browse every other medication we’ve checked against Rose Hip — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
212Moderate
0Minor
2,617No known interaction
Moderate

212 interactions

Showing 60 of 212 moderate interactions — see all 212 on the Rose Hip page.

No interaction 2,617 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Rose Hip and Alginic Acid, Aluminum Hydroxide Together: Common Questions

Can you take Rose Hip with Alginic Acid, Aluminum Hydroxide?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Rose Hip and Alginic Acid, Aluminum Hydroxide interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.