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Dietary supplement

Royal Jelly 100 mg Ingredients & Drug Interactions

by Indiana Botanic Gardens

Royal Jelly 100 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Royal Jelly 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Royal Jelly 100 mg is a dietary supplement by Indiana Botanic Gardens with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Royal Jelly 100 mg by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Royal Jelly 100 mg by Indiana Botanic Gardens — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Royal Jelly 100 mg by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Royal Jelly” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.

Royal Jelly 100 mg contains one active ingredient: royal jelly concentrate, a nutrient-rich secretion produced by honeybees. The softgel capsule also holds soybean oil, gelatin, yellow beeswax, and soy lecithin as inactive ingredients to hold and deliver the active component.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Royal Jelly's overall clinical evidence instead.

Moderate

Some clinical evidence supports Royal Jelly for:

Why this rating?
  • The label markets general wellness (“Helps boost vitality”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Menopausal symptoms — rated "Possibly Effective" (Natural Medicines).

Royal Jelly 100 mg shows possibly effective evidence for menopausal symptoms — meaning the data suggests it *might* help, but the evidence isn't definitive. For allergic rhinitis (hay fever), diabetes, and physical performance, the evidence rates as possibly ineffective.

Hair loss (androgenic alopecia) has insufficient reliable evidence in our data to rate either way.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal Jelly is generally well tolerated in most people. However, it can trigger serious allergic reactions in those with a personal history of asthma or atopy (a tendency toward allergic conditions).

Common allergic symptoms include itching, hives, eczema, shortness of breath, and oral allergy syndrome. In rare and severe cases — especially in people with asthma or atopy — royal jelly can cause life-threatening reactions such as anaphylaxis or status asthmaticus (severe asthma attack).

There's also one case report of hemorrhagic colitis (bleeding in the colon) with bloody diarrhea; symptoms resolved after stopping the supplement. During pregnancy and while breastfeeding, there isn't enough safety information, so the data advises against use in these situations.

Talk with your doctor or pharmacist about whether royal jelly is right for you if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take warfarin (Coumadin) or any blood thinner — royal jelly may increase your bleeding risk. Also double-check if you're on a blood pressure medication; royal jelly might lower your pressure further, which could cause dizziness or other problems.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Jelly 100 mg may be worth considering if you're looking to address menopausal symptoms and don't take blood thinners or blood pressure medications. If you do take warfarin or antihypertensive drugs, you'll need to clear this with your own doctor or pharmacist first — the interaction risk is real.

Skip it if you have a history of asthma or allergies; the allergic reaction risk is significant in that group.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Jelly 100 mg, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308830279
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 77269
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Jelly 100 mg by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
703308830279
IngredientAmount% DV
Royal Jelly100 mg--
Royal Jelly concentrate16.67 mg--

Other ingredients: Soybean Oil, Gelatin Capsule, yellow Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Helps boost vitality

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: For adults, take one (1) softgel one to three times daily, preferably with a meal, or as directed by a health care professional.

Best if used by date on bottle.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

Avoid this product if you are allergic to bee products.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store at room temperature.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Royal Jelly 100 mg by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Royal Jelly 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Royal Jelly 100 mg by Indiana Botanic Gardens

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Royal Jelly

Interacts with
174 drugs
100 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin Capsule, Yellow Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Jelly 100 mg by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Royal Jelly 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Royal Jelly 174

Individual Drug Interactions

The ingredients in Royal Jelly 100 mg interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Royal Jelly 100 mg interact with drugs. Each result below shows which ingredient is responsible. Royal Jelly

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Jelly 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
Royal Jelly full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Royal Jelly 100 mg, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Royal Jelly 100 mg by Indiana Botanic Gardens: Common Questions

Does Royal Jelly 100 mg by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Royal Jelly 100 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Jelly 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with hot flashes and night sweats?
Royal jelly rates as possibly effective for menopausal symptoms, which means the evidence suggests it *might* help with hot flashes and similar issues — but the data isn't bulletproof. You might see benefit, or you might not; individual results vary. Talk to your doctor about whether it's worth trying for your particular situation.
Is royal jelly safe if I have allergies or asthma?
No — if you have asthma or a history of allergies (atopy), royal jelly carries a real risk. People with these conditions report itching, hives, shortness of breath, and in rare severe cases, life-threatening allergic reactions. Skip this product if you fall into that group.
Can I take this while pregnant or breastfeeding?
There isn't enough safety information in our data to say it's okay either way. The evidence advises against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice based on your own situation.
What's royal jelly, and why is it in supplements?
Royal jelly is a nutrient-rich secretion honeybees produce to feed their queen bee. It contains proteins, vitamins, and other compounds; manufacturers add it to supplements because some of those compounds may offer health benefits — though for most uses, the evidence is weak or mixed.
Are there any common side effects I should know about?
In most people, royal jelly is well tolerated. If you don't have asthma or allergies, you're unlikely to have problems. People with allergies or asthma may experience itching, hives, eczema, or other allergic symptoms — and that's exactly why they should avoid it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Royal Jelly 100 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Jelly 100 mg label
Go deeper

The Full Monographs Behind Royal Jelly 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Royal Jelly

Interacts with 174 drugs

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limit...

Read the full Royal Jelly monograph →
Sources

Sources & How We Checked

Royal Jelly 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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