SAM-e Joint By Jarrow Formulas Overview & Drug Interactions
Check For Interactions With SAM-e Joint
Supplement: SAM-e Joint by Jarrow Formulas
SAM-e Joint Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Glucosamine HCl
Glucosamine is a natural compound found in the body, particularly in the fluid that surrounds joints. It is often used as a dietary supplement to help with joint health, particularly for conditions such as osteoarthritis. Glucosamine is believed to work by helping to reduce inflammation, promoting the repair of damaged cartilage, and slowing down the loss of cartilage. There are several different forms of glucosamine supplements, including glucosamine sulfate, glucosamine hydrochloride, and N-acetyl-glucosamine. Glucosamine sulfate is the most commonly used form in supplements. It is important to note that glucosamine sulfate is derived from shellfish (specifically the exoskeletons of shrimp, lobster, and crabs) and can be problematic for people with shellfish allergies.
See More Information Regarding Glucosamine| Ingredient Group | Glucosamine Hydrochloride |
|---|---|
| Category | non-nutrient/non-botanical |
S-Adenosyl Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
SAM-e Tosylate Disulfate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAM-e Joint by Jarrow Formulas
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 790011200192 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| Glucosamine HCl |
525 mg
|
Glucosamine Hydrochloride |
--
|
| S-Adenosyl Methionine |
200 mg
|
SAMe |
--
|
| SAM-e Tosylate Disulfate |
400 mg
|
SAMe |
|
| Other Ingredients: |
Cellulose
Enteric Coating
Forms
Glyceryl Behenate
Silicon Dioxide
Talc
Magnesium Silicate
Triethyl Citrate
Magnesium Stearate
Titanium Dioxide
Sorbitan Oleate
yellow Ochre
Red Iron Oxide
|
|---|
Label Statments:
| General Statements |
- Made in Italy
- SAM-e and glucosamine are known to benefit joint function and recuperation. Contains More of the Active S,S Form
SAM-e
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.
- Highest Concentration of Active S,S Form
- Promotes:
Joint Strength*
Liver Detoxification*
Mood and Brain Function*
- Enteric-Coated Tablets
- This product complies with the proposed USP Monograph for SAM-e.
- Glucosamine
Glucosamine is an aminosaccharide synthesized by transamidase enzymes from glucose and an amine group from glutamine. HCl (hydrochloric acid) stabilizes the glucosamine in this product. Glucosamine is a component of joint and intestinal tissue and is involved in the production of synovial fluid that lubricates the joints.*
SAM-e has been clinically shown to have the following benefits:
Joint Strength*
SAM-e supports the production of healthy connective tissue through transulfuration.* In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.*
Brain Metabolism*
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin).*
Liver*
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione- S-transferase), which are substances important for liver function.*
- FULL POTENCY
- In Foil Blister Pack
|
|---|---|
| Formula |
- S-Adenosyl Methionine + Glucosamine
- SAM-e + Glucosamine
- Contains: Shellfish (crab).
- Jarrow Formulas(R) SAM-e Joint(R) provides a full 200 mg SAM-e (net yield) and 525 mg of glucosamine hydrochloride in every enteric-coated tablet.
- Full potency 200 mg SAM-e is derived from 400 mg of SAM-e tosylate disulfate.
Jarrow Formulas(R) SAM-e Joint(R) is Joint Sustain(R) nutrition, providing glucosamine HCI, a SODIUM FREE form of glucosamine.
- 200 mg (net yield) SAM-e
525 mg Glucosamine HCI
|
| Suggested/Recommended/Usage/Directions |
- USAGE: Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
- For best results, use with Jarrow Formulas(R) JarroSil(R), the biologically Activated Silicon(R).
|
| Precautions |
- Individuals with Parkinson’s disease, bipolar disorder or manic depression should not use SAM-e.
- DO NOT use if seal of blister pack is broken.
- Contains: Shellfish (crab).
- WARNING: Do not use if allergic to shellfish.
- Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using.
- Keep out of the reach of children.
- Do not use if pregnant or nursing.
- Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
|
| General |
- 03513SAMJNT PROD # 120019
|
| Brand IP Statement(s) |
- Jarrow Formulas(R) SAM-e Joint(R) is foil blister-packed to maximize stability and safety.
- SAM-e Joint(R) is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
- (C) 2013 Jarrow FORMULAS(R)
- Jarrow Formulas(R) SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
|
| FDA Statement of Identity |
- DIETARY SUPPLEMENT
|
| Seals/Symbols |
- GLUTEN FREE
- v vegan
|
| Formulation |
- No wheat, no gluten, no soybeans, no dairy, no egg, no fish, no peanuts/tree nuts.
|
| Storage |
- Store in a cool, dry place.
|
| FDA Disclaimer Statement |
- *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
|
Brand Information
See all products by this brand
| Distributed Exclusively by | |
|---|---|
| Name | Jarrow Formulas Superior Nutrition and Formulation |
| Street Address | P.O. Box 35994 |
| City | Los Angeles |
| State | CA |
| ZipCode | 90035-4317 |
| Web Address | www.Jarrow.com |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.