SAMe 200 By Jarrow Formulas Overview & Drug Interactions
Check For Interactions With SAMe 200
Supplement: SAMe 200 by Jarrow Formulas
SAMe 200 Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
SAMe Tosylate Disulfate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAMe 200 by Jarrow Formulas
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 20 |
| UPC/BARCODE | 790011200147 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl Methionine |
200 mg
|
SAMe |
--
|
| SAMe Tosylate Disulfate |
400 mg
|
SAMe |
|
| Other Ingredients: |
Microcrystalline Cellulose
Mannitol
Hypromellose Acetate Succinate
Stearic Acid
Triethyl Citrate
Riboflavin
Glyceryl Behenate
Magnesium Stearate
Silicon Dioxide
Sodium Starch Glycolate
|
|---|
Label Statments:
| Formula |
- Natural SAMe 200
Jarrow Formulas SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
With more of the biologically active S,S than R,S form
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid), SAMe is a chiral molecule consisting of two forms: (S,S) SAMEe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R, S) structure is biologically inactive.
- Naturally Derived SAMe 200
S-Adenosyl methionine
Active S,S form
- Jarrow Formulas SAMe 200 is foil blister-packed to maximize stability and provides 200 mg of S-Adenosyl Methionine derived from 400 mg of SAMe Tosylate Disulfate.
- 200 mg (net yield) SAMe from 400 mg SAMe tosylate disulfate
- EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
|
|---|---|
| Formulation |
- Jarrow Formulas SAMe is made by microbiological fermentation and processed without chemical solvents to preserve 68-80% (S,S) SAMe.
SAMe Supports:
Brain Metabolism and Mood
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes. It also has been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood.
Joint Health
SAMe supports the production for healthy connective tissue through transsulfuration. In this transsulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.
Liver Function
SAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.
- Vegan
- Supports balanced mood, joint health, and liver function
- In foil blister pack
- Enteroguard coating
- Gluten free
- No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
- Regular Strength
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| Brand IP Statement(s) |
- Copyright 2023 Jarrow Formulas
|
| Suggested/Recommended/Usage/Directions |
- Suggested Use: Adults take 1 tablet 1-2 times a day on an empty stomach or as directed by your qualified healthcare professional.
|
| Precautions |
- Warning: Do not use if pregnant or nursing.
Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use.
- Individuals with Parkinson's disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinal upset in some persons.
- Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use.
Keep out of the reach of children.
- Do not use if safety seal or blister is broken, damaged or missing.
|
| Storage |
- Store in a cool, dry place.
|
| FDA Statement of Identity |
- Dietary Supplement
|
| General Statements |
- Mood support
|
Brand Information
See all products by this brand
| Distributed by | |
|---|---|
| Name | Jarrow Formulas, Inc. |
| City | Sherman Oaks |
| State | CA |
| Country | USA |
| ZipCode | 91403 |
| Phone Number | 1-866-459-4154 |
| Web Address | www.Jarrow.com |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.