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Dietary supplement

Seanol with BroccoRaphanin Ingredients & Drug Interactions

by Progressive Professional from Progressive Laboratories

Seanol with BroccoRaphanin label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Seanol with BroccoRaphanin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Seanol with BroccoRaphanin is a dietary supplement by Progressive Professional from Progressive Laboratories with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, heart and circulation health, blood sugar support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BroccoRaphanin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients. Seanol-P is an extract from Ecklonia Cava, a brown seaweed.

BroccoRaphanin is a concentrated broccoli extract. The capsule itself is made with rice flour and hypromellose (a plant-based binder).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Broccoli) (Natural Medicines).
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Ecklonia Cava) (Natural Medicines).

Seanol-P is possibly effective for high cholesterol. The evidence for its use in athletic performance, cancer prevention, and diabetes is not established.

BroccoRaphanin is possibly effective for colorectal cancer. Its role in other cancers, fibromyalgia, and other conditions is not yet established in the data we hold.

The evidence, ingredient by ingredient Ecklonia Cava Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Seanol-P has limited long-term safety data, and because seaweed can carry high iodine levels, the safety information advises against its use — especially if you have thyroid concerns or are pregnant or breastfeeding. A small number of trial participants reported hair loss, nausea, indigestion, or diarrhea.

BroccoRaphanin (broccoli as a food) is generally well tolerated, but concentrated extracts are less studied than the food itself. Loose stools, diarrhea, belly pain, and cramping have been reported with broccoli seed and sprout extracts, particularly at higher doses.

Broccoli is likely safe during pregnancy and breastfeeding, but there isn't enough data on file for Seanol-P to know either way — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Ecklonia Cava Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medications metabolized by CYP1A2 or CYP2A6 enzymes — these include some antiarrhythmics, antipsychotics, pain relievers, and smoking cessation drugs. The broccoli extract can reduce how well these drugs work.

Talk with your doctor or pharmacist to confirm your medications are safe to take alongside this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines two botanical extracts with limited evidence for most of their marketed uses. The broccoli component has documented interactions with medications your liver metabolizes, which may affect their effectiveness — so checking your prescriptions first is important.

Seanol-P has not been studied long-term, and iodine content is a concern. If you're considering this product, especially alongside any prescription medications, talk it over with your doctor or pharmacist beforehand.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Seanol with BroccoRaphanin, straight from the product label.

Brand Progressive Professional from Progressive Laboratories
Barcode (UPC) 351821011455
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261296
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
30
UPC/BARCODE
351821011455
IngredientAmount% DV
Seanol-P130 mg--
BroccoRaphanin20 mg--

Other ingredients: Rice Flour, Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Two vegetable capsules daily with meals, or more as directed by a health care professional.

General Statements

Sold only for dispensing by a licensed health care professional.

Precautions

Pregnant and/or lactatingwomen should consult their physician prior to use.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of reach of children.

Brand IP Statement(s)

Seanol-P is a registered trademark of Simply Healthy, LLC, BroccoRaphanin is produced under US patents 5,725,895; 5,968,505; 5,968,567; 6,177,122; 6,242,018; 6,521,818 and other US patents. Process patents pending to CS Health.

Progressive Professional from Progressive Laboratories

Formulation

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Seals/Symbols

GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 111

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Seanol with BroccoRaphanin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Seanol-P

No known
interactions
130 mg per serving Form: Ecklonia cava extract

Ecklonia cava is an edible brown seaweed rich in plant compounds called phlorotannins that are studied as antioxidants. Early human and lab research h...

Seanol-P monograph & interactions

BroccoRaphanin

Interacts with
187 drugs
20 mg per serving Form: Sulforophane Glucosinolate

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

BroccoRaphanin monograph & interactions

Other (inactive) ingredients: Rice Flour, Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories Drug Interactions

Want to check YOUR meds against Seanol with BroccoRaphanin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

BroccoRaphanin 187

Individual Drug Interactions

The ingredients in Seanol with BroccoRaphanin interact with 187 drugs. Click any drug to see the details.

1 of the 2 ingredients in Seanol with BroccoRaphanin interact with drugs. Each result below shows which ingredient is responsible. BroccoRaphanin

Each ingredient & the kinds of drugs it affects

For each ingredient in Seanol with BroccoRaphanin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BroccoRaphanin2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
BroccoRaphanin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Seanol with BroccoRaphanin, from the product label.

Progressive Professional from Progressive Laboratories

See all Progressive Professional from Progressive Laboratories products
Name
Progressive Laboratories, Inc.
City
Irving
State
Texas
ZipCode
75038
Phone Number
1-800-527-9512
Pharmacist Counseling Corner

Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories: Common Questions

Does Seanol with BroccoRaphanin by Progressive Professional from Progressive Laboratories interact with any medications?
Yes. Based on its ingredients, Seanol with BroccoRaphanin has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Seanol with BroccoRaphanin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Seanol safe during pregnancy?
There isn't enough safety data on file for Seanol-P during pregnancy to know either way. Because seaweed can carry high iodine levels, the safety information advises against it. Talk with your doctor or pharmacist for personalized advice before taking this product if you're pregnant or planning to become pregnant.
What is Seanol-P, and what does it do?
Seanol-P is an extract from Ecklonia Cava, a brown seaweed. It's possibly effective for high cholesterol, but evidence for other uses like athletic performance, cancer prevention, and diabetes is not yet established.
Can I take this if I'm breastfeeding?
Seanol-P has no reliable safety data during breastfeeding and should be avoided. BroccoRaphanin (broccoli) is likely safe during breastfeeding, but the combination product hasn't been studied in nursing mothers — talk with your doctor or pharmacist before taking it.
What side effects have been reported?
A small number of trial participants reported hair loss with Seanol-P, and a few reported nausea, indigestion, or diarrhea. With the broccoli extract, loose stools, diarrhea, belly pain, and cramping have been reported, especially at higher doses.
Does this product help with cancer?
BroccoRaphanin is possibly effective for colorectal cancer. Evidence for its use in other cancers is not yet established. Seanol-P has insufficient evidence for cancer prevention.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Seanol with BroccoRaphanin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Seanol with BroccoRaphanin label
Go deeper

The Full Monographs Behind Seanol with BroccoRaphanin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ecklonia Cava

Ecklonia cava is an edible brown seaweed rich in plant compounds called phlorotannins that are studied as antioxidants. Early human and lab research hints at possible benefits for blood vess...

Read the full Ecklonia Cava monograph → Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Seanol with BroccoRaphanin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ecklonia Cava 1 reference
  1. Lee DH, Park MY, Shim BJ, et al. Effects of Ecklonia cava polyphenol in individuals with hypercholesterolemia: a pilot study. J Med Food. 2012;15(11):1038-44.

See these in context on the Ecklonia Cava monograph →

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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