Selenium 200 mcg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Selenium 200 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Selenium 200 mcg is a dietary supplement by Nature's Blend with 1 active ingredient. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 321 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Selenium 200 mcg by Nature's Blend
Ask about any prescription or over-the-counter medication and we check it for interactions with Selenium 200 mcg by Nature's Blend — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Selenium 200 mcg by Nature's Blend
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: selenium at 200 micrograms per tablet. Selenium is a mineral your body needs in small amounts for healthy thyroid function, immune support, and antioxidant protection.
The tablet also contains inactive ingredients — calcium phosphate, cellulose, croscarmellose sodium, magnesium stearate, and silica — which are fillers and binders that help hold the tablet together.
Does it work?
Strong evidence
Selenium is likely effective for treating selenium deficiency, which is uncommon in well-nourished populations but can happen in certain regions or medical conditions. The evidence also suggests it may be possibly effective for Kashin-Beck disease (a joint condition linked to selenium deficiency), pre-eclampsia (high blood pressure in pregnancy), and autoimmune thyroiditis (an autoimmune thyroid condition).
However, it appears possibly ineffective for dyslipidemia (abnormal blood fat levels).
How safe is it?
Well-documented data
Selenium at this dose (200 mcg) is generally well-tolerated when you stay below the upper safe limit of 400 mcg daily. The most common side effects at normal doses are mild — gastric discomfort, headache, and rash.
However, excess selenium is toxic and can cause hair loss, nail damage, nausea, vomiting, fatigue, and skin problems. In rare cases, very high doses have caused serious multi-organ damage.
The safety data for pregnancy shows it's possibly safe, though there's also a possibly unsafe rating listed — talk with your doctor or pharmacist about whether it's right for you if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before taking this if you're on blood thinners or antiplatelet drugs — selenium may raise your bleeding risk (Moderate). Barbiturates (sedating medications), immunosuppressants, warfarin (Coumadin), birth control pills, and niacin supplements all have documented interactions and should be reviewed with your pharmacist beforehand.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
If you have selenium deficiency or are interested in the possibly effective uses (Kashin-Beck disease, pre-eclampsia, or autoimmune thyroiditis), this supplement may be worth considering — but only at the recommended dose and with your doctor's okay. Anyone taking blood thinners, sedating drugs, immunosuppressants, or other regular medications should check with their pharmacist or doctor before adding this in.
Pregnant or breastfeeding folks should also talk it over with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Selenium 200 mcg, straight from the product label.
| Brand | Nature's Blend |
|---|---|
| Barcode (UPC) | 079854011630 |
| Net contents | 100 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 274699 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Selenium 200 mcg by Nature's Blend, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Selenium | 200 mcg | 364% |
Other ingredients: Calcium Phosphate, Cellulose, Croscarmellose Sodium, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Precautions
Keep out of the reach of children.
Double safety sealed for your protection. Do not use if either seal is broken or missing.
Formulation
Preservative & gluten free. No sugar, starch, artificial colors, artificial flavors, wheat, or corn added.
This product is manufactured under strict quality control guidelines; therefore, purity and label potency are guaranteed. Made in USA & American Owned
General Statements
Questions/Comments Call 1-800-682-9862
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one tablet daily, preferably with a meal.
Formula
Selenium is an essential trace mineral important for cognitive function and may support a healthy immune system.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Selenium 200 mcg by Nature's Blend label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Selenium 200 mcg by Nature's Blend
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.
Selenium
Interacts with321 drugs
Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...
Selenium monograph & interactionsOther (inactive) ingredients: Calcium Phosphate, Cellulose, Croscarmellose Sodium, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Selenium 200 mcg by Nature's Blend Drug Interactions
HelloPharmacist Interaction Report
Nature's Blend Selenium 200 mcg does interact with several medication types.
Through its selenium content, the most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs — selenium may increase bleeding risk by thinning your blood further or making platelets less sticky.
Read the full breakdown — every affected drug type, severity by severity
Selenium can also interfere with immunosuppressants (drugs that deliberately weaken your immune system), potentially reducing how well they work, and with barbiturates (sedating drugs), which it may make work longer or stronger than intended. There's also a theoretical concern with warfarin (Coumadin), a specific blood thinner — selenium might change how your body handles it.
Birth control pills and niacin (a B vitamin used for cholesterol) may be affected too, though these are Minor concerns.
Altogether, these interactions span 321 individual medications. You'll want to run any blood thinners, sedating medications, immunosuppressants, or other regular prescriptions through the interaction checker below before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Selenium 200 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Selenium 200 mcg interact with 321 drugs. Click any drug to see the details.
1 of the 1 ingredient in Selenium 200 mcg interact with drugs. Each result below shows which ingredient is responsible. Selenium
DeucravacitinibSotyktu
How Deucravacitinib interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Deucravacitinib interactionDexamethasoneDecadron, Dexone, Dextenza, Dexycu, Hemady, Hexadrol +1 more
How Dexamethasone interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Dexamethasone interactionDiclofenacZorvolex
How Diclofenac interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diclofenac interactionDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
How Diclofenac Potassium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diclofenac Potassium interactionDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
How Diclofenac Sodium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diclofenac Sodium interactionDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
How Diclofenac Sodium, Misoprostol interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
How Diclofenac Epolamine interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diclofenac Epolamine interactionDicumarolDicumarol
How Dicumarol interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Dicumarol interactionDicyclomine, PhenobarbitalBentyl w/ Pb
How Dicyclomine, Phenobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Dicyclomine, Phenobarbital interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
How Diphenhydramine Hydrochloride, Naproxen Sodium interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Diphenhydramine Hydrochloride, Naproxen Sodium interactionDipyridamoleDipyridamole, Persantin, Persantin Injection, Persantin Retard, Persantine
How Dipyridamole interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Dipyridamole interactionDiroximel FumarateVumerity
How Diroximel Fumarate interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Diroximel Fumarate interactionDurvalumabImfinzi
How Durvalumab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Durvalumab interactionDyphylline, Ephedrine, Guaifenesin, PhenobarbitalLufyllin-EPG
How Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interactionEculizumabSoliris
How Eculizumab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Eculizumab interactionEdoxabanSavaysa
How Edoxaban interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Edoxaban interactionEfalizumabRaptiva
How Efalizumab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Efalizumab interactionEffientPrasugrel
How Effient interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Effient interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Efgartigimod Alfa-fcab interactionElranatamabElrexfio
How Elranatamab interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Elranatamab interactionEmapalumab-lzsgGamifant
How Emapalumab-lzsg interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Emapalumab-lzsg interactionEnoxaparinLovenox
How Enoxaparin interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Enoxaparin interactionEpcoritamab-byspEpkinly
How Epcoritamab-bysp interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Epcoritamab-bysp interactionEphedrine, Guaifenesin, Phenobarbital, TheophyllineMudrane GG
How Ephedrine, Guaifenesin, Phenobarbital, Theophylline interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionEphedrine, Phenobarbital, Potassium Iodide, TheophyllineMudrane, Quadrinal
How Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interactionEphedrine, Phenobarbital, TheophyllineTedral
How Ephedrine, Phenobarbital, Theophylline interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Ephedrine, Phenobarbital, Theophylline interactionEptifibatideIntegrilin
How Eptifibatide interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Eptifibatide interactionErgotamine, Belladonna, PhenobarbitalBellamine, Bellaspas, Eperbel-S
How Ergotamine, Belladonna, Phenobarbital interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Ergotamine, Belladonna, Phenobarbital interactionEsomeprazole, NaproxenVimovo
How Esomeprazole, Naproxen interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Esomeprazole, Naproxen interactionEtanercept-szzsErelzi
How Etanercept-szzs interacts with Selenium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Etanercept-szzs interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Selenium 200 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Selenium
Anticoagulant/Antiplatelet Drugs
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.
Barbiturates
Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.
Immunosuppressants
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.
Warfarin (Coumadin)
Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.
Contraceptive Drugs
Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.
Niacin
Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.
Brand information
Manufacturer and brand details for Selenium 200 mcg, from the product label.
Nature's Blend
See all Nature's Blend products- Name
- National Vitamin Company
- City
- Casa Grande
- State
- AZ
- ZipCode
- 85122
- Phone Number
- 1-800-682-9862
- Web Address
- www.nationalvitamin.com
Selenium 200 mcg by Nature's Blend: Common Questions
Does Selenium 200 mcg by Nature's Blend interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is 200 mcg of selenium safe to take every day?
What are the side effects of selenium at this dose?
Can I take this if I'm pregnant?
Can I take this if I'm breastfeeding?
Does selenium actually work for thyroid problems?
Will this interact with my birth control?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Selenium 200 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Selenium 200 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Selenium 200 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Selenium 36 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
- Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
- Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
- Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
- Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
- Capel ID, Jenner M, Williams DC, et al. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem 1981;14:729-32. PubMed
- Contempre B, Dumont JE, Ngo B, et al. Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. J Clin Endocrinol PubMed
- Hofbauer LC, Spitzweg C, Magerstadt RA, Heufelder AE. Selenium-induced thyroid dysfunction. Postgrad Med J 1997;73:103-4. PubMed
- Debski B, Milner JA. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem 2004;15:548-53. PubMed
- Ishikawa M, Sasaki M, Koiwai K, et al. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J Pharmacobiodyn 1992;15:377-85. PubMed
- Lippmann SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). JAMA 2009;301:39-51. DOI
- Reid SM, Middleton P, Cossich MC, Crowther CA. Interventions for clinical and subclinical hypothyroidism in pregnancy. Cochrane Database Syst Rev 2010;(7):CD007752. PubMed
- Vinceti, M., Wei, E. T., Malagoli, C., Bergomi, M., and Vivoli, G. Adverse health effects of selenium in humans. Rev.Environ.Health 2001;16(4):233-251. PubMed
- Abrams, C. K., Siram, S. M., Galsim, C., Johnson-Hamilton, H., Munford, F. L., and Mezghebe, H. Selenium deficiency in long-term total parenteral nutrition. Nutr Clin Pract 1992;7(4):175-178. PubMed
- Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. Forensic Sci Int 8-24-2007;171(1):67-72. PubMed
- Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol.Metab 2007;92(4):1263-1268. PubMed
- Alexander, J. Selenium. Novartis.Found.Symp 2007;282:143-149.
- Salonen, J. T., Salonen, R., Seppanen, K., Rinta-Kiikka, S., Kuukka, M., Korpela, H., Alfthan, G., Kantola, M., and Schalch, W. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial
- Kupka, R., Mugusi, F., Aboud, S., Msamanga, G. I., Finkelstein, J. L., Spiegelman, D., and Fawzi, W. W. Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and chil
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