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Dietary supplement

Serradrene Ingredients & Drug Interactions

by Desert Burn

Serradrene label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Serradrene against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Serradrene is a dietary supplement by Desert Burn with 1 active ingredient. Its ingredients are commonly taken for inflammation and swelling, sinus and respiratory congestion, pain after surgery or injury.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Serrapeptase. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Serradrene by Desert Burn

Ask about any prescription or over-the-counter medication and we check it for interactions with Serradrene by Desert Burn — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Serradrene by Desert Burn

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Serrapeptase.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Serradrene, straight from the product label.

Brand Desert Burn
Net contents 1 Veggie Capsule(s)
Market status Off market
Date entered into DSLD Mar 23, 2012
DSLD ID 7028
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Serradrene by Desert Burn, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
IngredientAmount% DV
Serrapeptase450 mg--

Other ingredients: Vegetable Cellulose, Rice Flour, hydroxpropyl methylcellulose phthalate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

CAUTION: Do not exceed recommended dose.

Do not purchase if seal is broken or missing.

Keep out of the reach of children.

Do not use this product if you are taking any type of blood platelet inhibitors to include but not limited to: Ticlid, Palvix or Coumadin or any other prescription drugs. This product is not to be used by pregnant or nursing mothers, children under 18, or any individual with a known medical condition.

Discontinue use if you experience stomach cramps or dry eyes as some people may e sensitive to serrapeptase enzyme.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement take one Serradrene(TM) vegetarian capsule at bedtime with a glass of water or as directed by your healthcare professional. Discontinue use if you experience stomach cramps dry eyes as some people may be sensitive to serrapeptase enzyme.

Storage

Store Serradrene(TM) in a cool, dry place.

General Statements

To report an adverse event: 1-702-997-2531.

LAB CERTIFIED (butterfly) PROFESSIONAL GRADE SERRAPEPTASE ENZYME (butterfly)

THE ORIGINAL SERRAPEPTASE

POWERFUL 40,000 I.U. / MICRO ENTERIC COATED POWDER

FAST ACTING 40,000 IU

Serrapeptase is a powerful enzyme which was discovered by Japanese and European scientists investigating the process by which a silkworm is able to dissolve it's cocoon and emerge as a butterfly. Serrapeptase is now commercially produced through a unique fermentation process and available as a dietary supplement to happy customers around the world.

Since 2004 we have set the standard for Serrapeptase supplements worldwide.

JOB 22:25 Yea, the Almighty shall be thy defence, and thou shalt have plenty of silver.

REAL SERRAPEPTASE

FDA Statement of Identity

DIETARY SUPPLEMENT

Formulation

Contains no milk or milk by-products, gluten, sugar, yeast, artificial colors, dyes, flavors, or preservatives.

100% VEGETARIAN

FDA Disclaimer Statement

The statements on this label have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

(C)2004-2010 Copyright DESERT BURN(R) All Rights Reserved.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Serradrene by Desert Burn label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Serradrene label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Serradrene by Desert Burn

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Serrapeptase

Interacts with
122 drugs
450 mg per serving

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you...

Serrapeptase monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Rice Flour, Hydroxpropyl methylcellulose phthalate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Serradrene by Desert Burn Drug Interactions

Serradrene contains a single active ingredient, and it has known interactions with 122 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Serradrene?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Serrapeptase 122

Individual Drug Interactions

The ingredients in Serradrene interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Serradrene interact with drugs. Each result below shows which ingredient is responsible. Serrapeptase

Each ingredient & the kinds of drugs it affects

For each ingredient in Serradrene with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Serrapeptase1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleeding.
In vitro research shows that serrapeptase has fibrinolytic activity.

Likelihood Possible Evidence D
Serrapeptase full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Serradrene, from the product label.

Desert Burn

See all Desert Burn products
Name
DESERT BURN(R)
Street Address
9030 W. SAHARA AVE #665
City
LAS VEGAS
State
NV
ZipCode
89117
Pharmacist Counseling Corner

Serradrene by Desert Burn: Common Questions

Does Serradrene by Desert Burn interact with any medications?
Yes. Based on its ingredients, Serradrene has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Serradrene contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Serradrene is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Serradrene label
Go deeper

The Full Monographs Behind Serradrene’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Serrapeptase

Interacts with 122 drugs

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you want to try it, choose an enteric-coate...

Read the full Serrapeptase monograph →
Sources

Sources & How We Checked

Serradrene's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serrapeptase 2 references
  1. Tachibana M, Mizukoshi O, Harada Y, et al. A multi-centre, double-blind study of serrapeptase versus placebo in post-antrotomy buccal swelling. Pharmatherapeutica 1984;3:526-30..
  2. Mazzone A, Catalani M, Costanzo M, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990;18:379-88.. PubMed

See these in context on the Serrapeptase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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