Shark Cartilage 740 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Shark Cartilage 740 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Shark Cartilage 740 mg is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for cancer support (popular use), arthritis and joint pain, psoriasis.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shark Cartilage Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Shark Cartilage 740 mg by Puritan's Pride
Ask about any prescription or over-the-counter medication and we check it for interactions with Shark Cartilage 740 mg by Puritan's Pride — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Shark Cartilage 740 mg by Puritan's Pride
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Shark Cartilage.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
- For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Shark Cartilage 740 mg, straight from the product label.
| Brand | Puritan's Pride |
|---|---|
| Barcode (UPC) | 074312165801 |
| Net contents | 100 Rapid Release Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 285982 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Shark Cartilage 740 mg by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Shark Cartilage Powder | 740 mg | -- |
Other ingredients: Dicalcium Phosphate, Gelatin, Vegetable Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Puritan’s Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.
USA 3004329138 EEC
To reorder item # 6580 www.puritan.com 1-800-645-1030
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if seal under cap is broken or missing.
Contains fish (shark) ingredients.
Storage
Store at room temperature.
Brand IP Statement(s)
Copyright 2020 Puritan’s Pride, Inc.
Seals/Symbols
QA Quality Assured
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) capsule four to six times daily, preferably with meals.
Formulation
No artificial color, flavor or sweetener, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no shellfish. Sodium free.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Shark Cartilage 740 mg by Puritan's Pride label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Shark Cartilage 740 mg by Puritan's Pride
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Shark Cartilage Powder
Interacts with121 drugs
Shark cartilage is a supplement made from the skeletal tissue of sharks that was heavily promoted for cancer and joint conditions, but good-quality cl...
Shark Cartilage Powder monograph & interactionsOther (inactive) ingredients: Dicalcium Phosphate, Gelatin, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Shark Cartilage 740 mg by Puritan's Pride Drug Interactions
Shark Cartilage 740 mg contains a single active ingredient, and it has known interactions with 121 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Shark Cartilage 740 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Shark Cartilage 740 mg interact with 121 drugs. Click any drug to see the details.
1 of the 1 ingredient in Shark Cartilage 740 mg interact with drugs. Each result below shows which ingredient is responsible. Shark Cartilage Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Abrocitinib interactionAdalimumabHumira
How Adalimumab interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Alemtuzumab interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Azathioprine interactionBasiliximabSimulect
How Basiliximab interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Beclomethasone Dipropionate interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Betamethasone Valerate interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Bimekizumab-bkzx interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Ciclesonide interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Cisplatin interactionCladribineLeustatin, Mavenclad
How Cladribine interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Cladribine interactionCopanlisibAliqopa
How Copanlisib interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Copanlisib interactionCortisone AcetateCortisone Tablets, Cortone
How Cortisone Acetate interacts with Shark Cartilage 740 mg — through 1 ingredient. Tap an ingredient for the detail:
Shark Cartilage PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage Powder + Cortisone Acetate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Shark Cartilage 740 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Shark Cartilage Powder
Immunosuppressants
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
In vitro evidence suggests that shark cartilage might stimulate immune responses. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Shark Cartilage 740 mg, from the product label.
Puritan's Pride
See all Puritan's Pride products- Name
- Puritan's Pride, Inc.
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-800-645-1030
- Web Address
- www.puritan.com
Shark Cartilage 740 mg by Puritan's Pride: Common Questions
Does Shark Cartilage 740 mg by Puritan's Pride interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Shark Cartilage 740 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Shark Cartilage 740 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Shark Cartilage 740 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Shark Cartilage 12 references
- Ashar B, Vargo E. Shark cartilage-induced hepatitis [letter]. Ann Intern Med 1996;125:780-1. PubMed
- Lane IW, Comac L. Sharks don't get cancer. Garden City, NY: Avery Publishing Group; 1992.
- Miller DR, Anderson GT, Stark JJ, et al. Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer. J Clin Oncol 1998;16:3649-55. PubMed
- Leitner SP, Rothkopf MM, Haverstick L, et al. Two phase II studies of oral dry shark cartilage powder (SCP) in patients (pts) with either metastatic breast or prostate cancer refractory to standard treatment. Proc Am Soc Clinical Oncol 1998;17:A240.
- Batist G, Patenaude F, Champagne P, et al. Neovastat (AE-941) in refractory renal cell carcinoma patients: report of a phase II trial with two dose levels. Ann Oncol 2002;13:1259-63..
- Merly, L., Simjee, S., and Smith, S. L. Induction of inflammatory cytokines by cartilage extracts. Int Immunopharmacol. 2007;7(3):383-391. PubMed
- Bargahi, A., Hassan, Z. M., Rabbani, A., Langroudi, L., Noori, S. H., and Safari, E. Effect of shark cartilage derived protein on the NK cells activity. Immunopharmacol.Immunotoxicol. 2011;33(3):403-409. PubMed
- Leitner SP, Rothkopf MM, Haverstick DD, and et al. Two phase II studies of oral dry shark cartilage powder (SCP) in patients with either metastatic breast or prostate cancer refractory to standard treatment. Amer Soc Clin Oncol 1998;17:A240.
- Milner M. A guide to the use of shark cartilage in the treatment of arthritis and other inflammatory joint diseases. Amer Chiropractor 1999;21:40-42.
- Rosenbluth, RJ, Jennis, AA, Cantwell, S, and et al. Oral shark cartilage in the treatment of patients with advanced primary brain tumors. A phase II pilot study (meeting abstract). Proc Annu Meet Am Soc Clin Oncol 1999;18:A554.
- Saad F, Klotz L, Babaian R, Lacombe L, Champagne P, and Dupont E. Phase I/II trial on AE-941 (Neovastat) in patients with metastatic refractory prostate cancer (abstract presentation). Canadian Urological Association Annual Meeting (June 24-27, 2001).
- Merly L, Smith SL. Pro-inflammatory properties of shark cartilage supplement. Immunopharmacol Immunotoxicol. 2015;37(2):140-7. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC