Siberian Cocklebur Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Siberian Cocklebur against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Siberian Cocklebur is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for nasal congestion and sinus problems, allergic rhinitis (hay fever), headache.Based on those ingredients, 662 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Siberian Cocklebur dried fruit liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Siberian Cocklebur by Herbal Terra
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Siberian Cocklebur by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Siberian cocklebur dried fruit liquid extract. The inactive ingredient is menstruum, a liquid used to extract and preserve the herb.
The fruit itself has been used in traditional medicine, but it contains toxic compounds that can pose serious health risks.
Does it work?
Couldn't assess
We hold no effectiveness data for Siberian cocklebur in our records. That doesn't mean the herb has no traditional uses, but the evidence for its benefits isn't established in the data we have available.
How safe is it?
Well-documented data
Siberian cocklebur is considered unsafe for use. The fruit contains toxic compounds and has caused serious poisoning; it requires careful processing and professional oversight that's difficult to verify in over-the-counter products.
Any potential benefit is unlikely to outweigh the toxicity risk. Adverse effects can be severe and develop quickly.
Within hours of taking the seeds or seedlings, people have experienced abdominal pain, nausea, vomiting, dangerous low blood sugar, liver damage (shown by elevated liver function tests), increased bleeding risk, drowsiness, dizziness, shortness of breath, sweating, fever, and irregular heartbeats (palpitations). In serious cases, symptoms have progressed to metabolic acidosis (dangerous blood pH imbalance), worsening blood sugar swings, heart rhythm problems (arrhythmia), elevated heart enzymes, and in fatal cases, immune cell infiltration in the heart muscle.
The safety data advises against use during pregnancy and while breastfeeding due to potential toxicity and unknown safety.
Meds to double-check
Major interaction found
Before taking Siberian cocklebur, double-check with your doctor or pharmacist if you take any diabetes medications (Major risk of severe low blood sugar), any drugs that can damage the liver (Major risk of compounded liver injury), or any drugs that can harm the kidneys (Major risk of compounded kidney damage). The interaction list is extensive — use the search tool on this page to verify your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Siberian cocklebur is rated unsafe for use — the serious toxicity risks outweigh any claimed benefits. If you're taking any medications, especially for diabetes, liver disease, kidney disease, or any drug known to affect the liver or kidneys, this product poses a Major interaction risk.
Talk with your doctor or pharmacist before considering this supplement.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Siberian Cocklebur, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 617503353108 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 234374 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Siberian Cocklebur by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Siberian Cocklebur dried fruit liquid extract | 970 mg | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Manufactured in the USA in an FDA registered facility
Sugar free
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
Formula
Xanthium strumarium
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Siberian Cocklebur by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Siberian Cocklebur by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Siberian Cocklebur dried fruit liquid extract
Interacts with662 drugs
Siberian cocklebur is a fruit used in traditional Chinese and other Asian herbal medicine, mainly for nasal congestion, sinus issues, and allergies. H...
Siberian Cocklebur dried fruit liquid extract monograph & interactionsOther (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Siberian Cocklebur by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Siberian Cocklebur by Herbal Terra interacts with a significant number of medications, and the interactions are serious.
The single active ingredient — Siberian cocklebur dried fruit liquid extract — has documented Major-severity interactions with three key drug types: drugs that can damage the kidneys (nephrotoxic drugs), drugs that can damage the liver (hepatotoxic drugs), and diabetes medications.
Read the full breakdown — every affected drug type, severity by severity
With nephrotoxic drugs like cyclosporine and aminoglycosides (gentamicin, amikacin), combining them with Siberian cocklebur could compound kidney damage. The herb itself can harm kidney function, so using it alongside other kidney-damaging medications raises the risk.
With hepatotoxic drugs — medications that can injure the liver, such as acarbose, amiodarone, and atorvastatin — the risk is especially serious. Siberian cocklebur has been linked to liver toxicity and even liver failure in reported cases, and pairing it with other liver-damaging drugs could significantly increase that danger.
With diabetes medications (like glimepiride and glyburide), there's a Major risk of dangerous low blood sugar (hypoglycemia). Siberian cocklebur seeds and seedlings have caused severe, worsening low blood sugar in humans, sometimes within hours.
Altogether, these interactions span 663 individual medications. Before you take this product, use the search tool below to check every prescription and over-the-counter medication you're on.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Siberian Cocklebur?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Siberian Cocklebur interact with 662 drugs. Click any drug to see the details.
1 of the 1 ingredient in Siberian Cocklebur interact with drugs. Each result below shows which ingredient is responsible. Siberian Cocklebur dried fruit liquid extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractAntidiabetes Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Siberian Cocklebur — through 1 ingredient. Tap an ingredient for the detail:
Siberian Cocklebur Dried Fruit Liquid ExtractNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur Dried Fruit Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Siberian Cocklebur with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Siberian Cocklebur dried fruit liquid extract
Antidiabetes Drugs
Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans. Hypoglycemia occurs soon after consumption and worsens with time in most cases. Do not use Siberian cocklebur in people taking medications that also lower blood glucose.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Hepatotoxic Drugs
Siberian cocklebur can adversely affect the liver. It has been linked to many cases of hepatotoxicity and some cases of liver failure. Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage. Some of these drugs include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (TriCor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo).
Nephrotoxic Drugs
Siberian cocklebur can adversely affect the kidney. Theoretically, combining Siberian cocklebur with potentially nephrotoxic drugs might have additive harmful effects on kidney function.
Some potentially nephrotoxic drugs include cyclosporine (Neoral, Sandimmune); aminoglycosides including amikacin (Amikin), gentamicin (Garamycin, Gentak, others), and tobramycin (Nebcin, others); nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene); and numerous others.
Brand information
Manufacturer and brand details for Siberian Cocklebur, from the product label.
Siberian Cocklebur by Herbal Terra: Common Questions
Does Siberian Cocklebur by Herbal Terra interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Siberian Cocklebur is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Siberian Cocklebur’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Siberian Cocklebur's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Siberian Cocklebur 4 references
- Wu, M. L., Wang, C. P., and Deng, J. F. Fatal hepatic failure due to fructus xanthii in a child. Abstracts of the 2005 North American Congress of Clinical Toxicology Annual Meeting. Clin Toxicol 2005;43:639. DOI
- Gurley ES, Rahman M, Hossain MJ, et al. Fatal outbreak from consuming Xanthium strumarium seedlings during time of food scarcity in northeastern Bangladesh. PLoS One 2010 Mar 18;5(3):e9756. PubMed
- Turgut M, Alhan CC, Gurgoze M, et al. Carboxyatractyloside poisoning in humans. Ann Trop Paediatr 2005;25(2):125-34. PubMed
- Karabiber H, Almis H, Selimoglu MA, Yakinci C, Yilmaz S. Xanthium strumarium poisoning requiring liver transplantation. J Pediatr Gastroenterol Nutr. 2014;58(1):e6-9.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC