Super S.G. Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Super S.G. against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Super S.G. is a dietary supplement by Princess Lifestyle with 10 active ingredients. Its ingredients are commonly taken for alcohol cravings and reduction, menopausal symptoms, heart and blood vessel health.Based on those ingredients, 1,453 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Scutellaria baicalensis, Paeonia lactiflora, Xanthium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Super S.G. by Princess Lifestyle
Ask about any prescription or over-the-counter medication and we check it for interactions with Super S.G. by Princess Lifestyle — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Super S.G. by Princess Lifestyle
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Super S.G. contains 10 ingredients, of which several are traditional botanicals. The checked active herbal ingredients are kudzu, peony, Baikal skullcap, red magnolia, Siberian cocklebur, and asarabacca.
There is also a proprietary blend listed, which means some ingredients are grouped and not itemized separately. The product also contains gelatin as an inactive ingredient (the capsule material) and gypsum, for which we hold no interaction data.
Does it work?
Not established
The evidence for this product's effectiveness is limited. Kudzu is rated possibly effective for alcohol use disorder, but the other ingredients lack reliable evidence or have not been rated for established health uses.
Peony, Baikal skullcap, red magnolia, and asarabacca all show insufficient evidence for the conditions they've been studied in, or no effectiveness data is on file. Because the product is a blend and we do not know the quantity of each ingredient, it is not possible to assess whether the formulation would deliver an effective dose of any single component.
How safe is it?
Well-documented data
Kudzu is generally well tolerated short-term, but long-term safety isn't established. Peony and Baikal skullcap are considered generally well tolerated for short-term use, though high-quality safety data are limited.
Reported side effects from peony include nausea, diarrhea, and abdominal discomfort, and from Baikal skullcap include abdominal pain, constipation, nausea, and vomiting. Red magnolia appears well tolerated in the limited data available.
Siberian cocklebur is generally regarded as unsafe due to serious poisoning risk, with initial effects including abdominal pain, nausea, vomiting, low blood sugar, drowsiness, dizziness, fever, and palpitations that can progress to metabolic acidosis and heart rhythm problems. Asarabacca, particularly when contaminated with aristolochic acid (a known nephrotoxin and carcinogen), poses a significant kidney and cancer risk.
Meds to double-check
Major interaction found
Before taking this product, check your medications against these drug types, especially if you take multiple ones from this list: any drugs that affect your kidneys (nephrotoxic drugs), any drugs that affect your liver (hepatotoxic drugs), diabetes medications, blood thinners or antiplatelet drugs (like warfarin or aspirin), blood pressure medications, birth control or hormone replacement therapy, caffeine-based products, sedating drugs, medications metabolized by your liver (especially those involving CYP enzymes), thyroid medications, methotrexate, tamoxifen, phenytoin, lithium, and clozapine. Do not use this product without discussing it with your pharmacist.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
This product carries serious safety concerns, especially due to the presence of Siberian cocklebur and asarabacca—both linked to organ damage and listed as unsafe or likely unsafe by major safety standards. Even the other ingredients interact with many common medications.
If you take any prescription drugs or have kidney or liver disease, talk with your pharmacist or doctor before considering this product. The evidence for effectiveness is not established.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Super S.G., straight from the product label.
| Brand | Princess Lifestyle |
|---|---|
| Barcode (UPC) | 687729000377 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 21, 2022 |
| DSLD ID | 268487 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Super S.G. by Princess Lifestyle, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1000 mg | -- |
| Gypsum | 0 NP | -- |
| Kudzu | 0 NP | -- |
| Paeonia lactiflora | 0 NP | -- |
| Scutellaria baicalensis | 0 NP | -- |
| Fragrant Angelica | 0 NP | -- |
| Balloon Flower | 0 NP | -- |
| Ligusticum chuanxiong | 0 NP | -- |
| Red Magnolia | 0 NP | -- |
| Xanthium | 0 NP | -- |
| Asarum | 0 NP | -- |
Other ingredients: Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended use: As a dietary supplement. In spring season, adults may take 3 capsules 3 times daily with warm water on an empty stomach one hour before meals. In other seasons, adults may take 3 capsules daily, children over 12 years old may take 2 capsules daily in all seasons.
Precautions
Not recommended for children under the age of 12. Keep out of reach of children.
Do not use if pregnant or nursing.
Results may vary. Consult your health care provider if need more help.
Storage
Warning: Store in a cool and dry place at room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Helps support healthy immune function
Manufactured in a certified food processor and quality assured facility.
General Statements
Best wishes for Spring Good
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Super S.G. by Princess Lifestyle label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Super S.G. by Princess Lifestyle
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Gypsum
- › Kudzu
- › Paeonia lactiflora
- › Scutellaria baicalensis
- › Fragrant Angelica
- › Balloon Flower
- › Ligusticum chuanxiong
- › Red Magnolia
- › Xanthium
- › Asarum
Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.
Super S.G. by Princess Lifestyle Drug Interactions
HelloPharmacist Interaction Report
Super S.G. by Princess Lifestyle contains multiple herbal ingredients with documented interactions with medications.
The most serious concern is Siberian cocklebur (Xanthium), which carries Major-severity interactions with drugs that affect the kidneys (nephrotoxic drugs), drugs that affect the liver (hepatotoxic drugs), and diabetes medications. Siberian cocklebur itself can damage both organs and cause severe low blood sugar (hypoglycemia), and combining it with medications that do the same could be dangerous.
Read the full breakdown — every affected drug type, severity by severity
The other checked ingredients—kudzu, peony (Paeonia lactiflora), Baikal skullcap (Scutellaria baicalensis), red magnolia, and asarabacca—carry Moderate-severity interactions. Kudzu may increase bleeding risk with blood thinners (anticoagulants or antiplatelets), raise caffeine levels, increase methotrexate toxicity, interfere with tamoxifen or estrogen therapy, and lower blood sugar with diabetes medications.
Peony may raise levels of certain medications metabolized by your liver, interfere with birth control or hormone therapy, increase bleeding risk, and affect the anticonvulsant phenytoin. Baikal skullcap may lower blood pressure with blood pressure drugs, raise caffeine and other drug levels, interfere with thyroid or diabetes medications, and increase bleeding risk.
Red magnolia may add to the effects of sedating drugs and increase bleeding risk. Asarabacca carries a Major-severity interaction with kidney-damaging drugs due to contamination with aristolochic acid, a nephrotoxic compound.
We could not check three other ingredients—gypsum, Fragrant Angelica, Balloon Flower, and Ligusticum chuanxiong—because we hold no interaction data for them. Altogether, these interactions span 1,432 individual medications.
Use the medication checker below to search your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Super S.G.?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Super S.G. interact with 1,453 drugs. Click any drug to see the details.
6 of the 10 ingredients in Super S.G. interact with drugs. Each result below shows which ingredient is responsible. Scutellaria baicalensis Paeonia lactiflora Xanthium Kudzu Asarum Red Magnolia
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Super S.G. — through 2 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + 6-mercaptopurine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Super S.G. — through 2 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Abacavir Sulfate, Dolutegravir, Lamivudine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Super S.G. — through 2 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Abacavir, Lamivudine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Super S.G. — through 3 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Abiraterone interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Abiraterone interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Super S.G. — through 3 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Abiraterone Acetate interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Abiraterone Acetate interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Super S.G. — through 3 ingredients. Tap an ingredient for the detail:
XanthiumAntidiabetes Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans.
Read the full Xanthium + Acarbose interactionScutellaria BaicalensisAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Baikal skullcap with antidiabetes drugs might enhance blood glucose lowering effects.
Read the full Scutellaria Baicalensis + Acarbose interactionKudzuAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Kudzu + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Super S.G. — through 3 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acebutolol interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acebutolol interactionScutellaria BaicalensisAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Scutellaria Baicalensis + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Aspirin interactionXanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Aspirin interactionKudzuAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu + Acetaminophen, Aspirin interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Aspirin interactionPaeonia LactifloraAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Lactiflora + Acetaminophen, Aspirin interactionRed MagnoliaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Red Magnolia + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Aspirin, Caffeine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Aspirin, Caffeine interactionScutellaria BaicalensisAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis + Acetaminophen, Aspirin, Caffeine interactionKudzuAnticoagulant/antiplatelet Drugs, Caffeine +1 Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu + Acetaminophen, Aspirin, Caffeine interactionRed MagnoliaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Red Magnolia + Acetaminophen, Aspirin, Caffeine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Butalbital interactionXanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Butalbital interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Butalbital interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Butalbital interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Butalbital, Caffeine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Butalbital, Caffeine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Butalbital, Caffeine interactionKudzuCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Acetaminophen, Butalbital, Caffeine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Butalbital, Caffeine, Codeine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Butalbital, Caffeine, Codeine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Butalbital, Caffeine, Codeine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Butalbital, Caffeine, Codeine interactionKudzuHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Butalbital, Caffeine, Codeine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Butalbital, Codeine interactionXanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Butalbital, Codeine interactionScutellaria BaicalensisCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis + Acetaminophen, Butalbital, Codeine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Butalbital, Codeine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Butalbital, Codeine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Butalbital, Codeine Phosphate interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Butalbital, Codeine Phosphate interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Butalbital, Codeine Phosphate interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Butalbital, Codeine Phosphate interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Butalbital, Codeine Phosphate interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionKudzuHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionScutellaria BaicalensisCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Codeine interactionXanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Caffeine, Codeine interactionScutellaria BaicalensisCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Codeine interactionKudzuCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Acetaminophen, Caffeine, Codeine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Caffeine, Codeine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Codeine, Salicylamide interactionKudzuCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Acetaminophen, Caffeine, Codeine, Salicylamide interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Codeine, Salicylamide interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Caffeine, Dihydrocodeine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Dihydrocodeine interactionKudzuHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Caffeine, Dihydrocodeine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Dihydrocodeine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Caffeine, Dihydrocodeine interactionScutellaria BaicalensisCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Isometheptene interactionXanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Caffeine, Isometheptene interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Isometheptene interactionKudzuCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Acetaminophen, Caffeine, Isometheptene interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Caffeine, Pyrilamine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Caffeine, Pyrilamine interactionKudzuCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Acetaminophen, Caffeine, Pyrilamine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Caffeine, Pyrilamine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Super S.G. — through 6 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionXanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionScutellaria BaicalensisCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionRed MagnoliaCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Red Magnolia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionXanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumHepatotoxic Drugs, Nephrotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the liver.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionPaeonia LactifloraCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
XanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Super S.G. — through 5 ingredients. Tap an ingredient for the detail:
AsarumNephrotoxic Drugs Major
Interaction Summary
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarum + Acetaminophen, Chlorpheniramine, Phenylephrine interactionXanthiumNephrotoxic Drugs, Hepatotoxic Drugs Major
Interaction Summary
Siberian cocklebur can adversely affect the kidney.
Read the full Xanthium + Acetaminophen, Chlorpheniramine, Phenylephrine interactionScutellaria BaicalensisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis + Acetaminophen, Chlorpheniramine, Phenylephrine interactionKudzuHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu + Acetaminophen, Chlorpheniramine, Phenylephrine interactionPaeonia LactifloraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Super S.G. with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Scutellaria baicalensis
Anticoagulant/Antiplatelet Drugs
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Preliminary clinical research suggests that taking capsules containing a combination of astragalus, goldthread, and Baikal skullcap daily for 4 weeks inhibits platelet aggregation; the effect seems to be similar to that of aspirin 50 mg daily. It is unclear if this effect is due to Baikal skullcap, other ingredients, or the combination.
Antidiabetes Drugs
Theoretically, concomitant use of Baikal skullcap with antidiabetes drugs might enhance blood glucose lowering effects.
Baicalein, a constituent of Baikal skullcap, has alpha-glucosidase inhibitory activity in vitro. Animal research also suggests that Baikal skullcap enhances the antidiabetic effects of metformin. However, in a small human study, taking Baikal skullcap extract did not enhance the antidiabetic effects of metformin, although it did modestly lower glucose levels during an oral glucose tolerance test (OGTT). Until more is known, use cautiously.
Antihypertensive Drugs
Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Animal research suggests that baicalein, a constituent of Baikal skullcap, might lower blood pressure.
Antithyroid Drugs
Theoretically, concomitant use of Baikal skullcap and antithyroid drugs may result in additive activity and increase the risk of hypothyroidism.
In an animal hyperthyroid model, Baikal skullcap improved levels of triiodothyronine (T3), thyroxine (T4), and thyroid stimulating hormone (TSH). The clinical significance of this effect is unclear.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
In vitro evidence suggests that constituents of Baikal skullcap inhibit the activity of CYP1A2. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Baikal skullcap might increase levels of drugs metabolized by CYP2C19 enzymes.
In vitro evidence suggest that wogonin, a constituent of Baikal skullcap, modestly inhibits the activity of CYP2C19 enzymes. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of Baikal skullcap might interfere with hormone replacement therapy, due to competition for estrogen receptors.
In vitro evidence suggests that Baikal skullcap has estrogenic activity.
Lithium
Theoretically, Baikal skullcap might reduce lithium excretion and increase serum levels of lithium.
Baikal skullcap is thought to have diuretic properties, which may reduce lithium excretion. The dose of lithium might need to be decreased.
Alcohol (Ethanol)
Theoretically, Baikal skullcap might potentiate the sedative effects of alcohol.
In vitro and animal research suggests that Baikal skullcap binds to GABA-A receptors and causes sedation. Theoretically, Baikal skullcap might potentiate the sedative effects of alcohol. Preliminary clinical research has not identified clinically relevant sedation after use of Baikal skullcap; however, a thorough evaluation of safety outcomes has not been conducted.
Cns Depressants
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
In vitro and animal research suggests that Baikal skullcap binds to GABA-A receptors and causes sedation. Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties. Preliminary clinical research has not identified clinically relevant sedation after use of Baikal skullcap; however, a thorough evaluation of safety outcomes has not been conducted.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, Baikal skullcap might alter the levels and clinical effects of OATP substrates.
Some pharmacokinetic research shows that baicalin, a constituent of Baikal skullcap, can decrease plasma levels of rosuvastatin. The mechanism is thought to involve stimulation of the activity of the organic anion-transporting polypeptide 1B1 (OATP1B1), which transports rosuvastatin into the liver. This decreases plasma levels of the drug, but increases levels at the site of action in the liver. The degree to which rosuvastatin levels are affected depends on the OATP1B1 haplotype of the individual. Baikal skullcap might also affect other OATP1B1 substrates.
P-Glycoprotein Substrates
Theoretically, Baikal skullcap might increase levels of drugs transported by P-glycoprotein.
In vitro and animal research suggests that baicalein, oroxylin A, and wogonin, constituents of Baikal skullcap, can inhibit P-glycoprotein. This effect has not been reported in humans.
Paeonia lactiflora
Anticoagulant/Antiplatelet Drugs
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.
Clozapine (Clozaril)
Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.
Contraceptive Drugs
Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.
Phenytoin (Dilantin)
Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.
Xanthium
Antidiabetes Drugs
Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans. Hypoglycemia occurs soon after consumption and worsens with time in most cases. Do not use Siberian cocklebur in people taking medications that also lower blood glucose.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Hepatotoxic Drugs
Siberian cocklebur can adversely affect the liver. It has been linked to many cases of hepatotoxicity and some cases of liver failure. Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage. Some of these drugs include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (TriCor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo).
Nephrotoxic Drugs
Siberian cocklebur can adversely affect the kidney. Theoretically, combining Siberian cocklebur with potentially nephrotoxic drugs might have additive harmful effects on kidney function.
Some potentially nephrotoxic drugs include cyclosporine (Neoral, Sandimmune); aminoglycosides including amikacin (Amikin), gentamicin (Garamycin, Gentak, others), and tobramycin (Nebcin, others); nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene); and numerous others.
Kudzu
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Asarum
Nephrotoxic Drugs
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects. Aristolochic acid can damage the kidneys and is deemed unsafe by the FDA, leading to the classification of products containing it as adulterated. When considering medications that may also pose a risk of kidney damage, caution is advised when combining them with asarabacca due to potential additive nephrotoxicity. It is advisable to consult healthcare professionals before using asarabacca alongside nephrotoxic drugs to minimize the risk of adverse effects on kidney function.
Red Magnolia
Anticoagulant/Antiplatelet Drugs
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.
Cns Depressants
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.
Brand information
Manufacturer and brand details for Super S.G., from the product label.
Princess Lifestyle
See all Princess Lifestyle products- Name
- Princess Lifestyle, LLC
- City
- Baldwin Park
- State
- CA
Super S.G. by Princess Lifestyle: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Super S.G. is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Super S.G.’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Kudzu
Interacts with 584 drugsKudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...
Read the full Kudzu monograph → Herb & supplement monographPeony
Interacts with 811 drugsPeony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...
Read the full Peony monograph → Herb & supplement monographBaikal Skullcap
Interacts with 946 drugsBaikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baicalin and baicalein studied mostly in the lab. Human...
Read the full Baikal Skullcap monograph → Herb & supplement monographMagnolia
Interacts with 351 drugsMagnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...
Read the full Magnolia monograph → Herb & supplement monographSiberian Cocklebur
Interacts with 662 drugsSiberian cocklebur is a fruit used in traditional Chinese and other Asian herbal medicine, mainly for nasal congestion, sinus issues, and allergies. Human evidence is very limited, and the p...
Read the full Siberian Cocklebur monograph → Herb & supplement monographAsarabacca
Interacts with 355 drugsAsarabacca is a European woodland plant traditionally used to clear the nose, cause sweating, or trigger vomiting, but it is rarely used today. It belongs to a plant family that often contai...
Read the full Asarabacca monograph →Sources & How We Checked
Super S.G.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 87 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Kudzu 21 references
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- Luo ZR, Zheng B. [Effect of Puerarin on platelet activating factors CD63 and CD62P, plasminogen activator inhibitor and C-reactive protein in patients with unstable angia pectoris]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2001;21:31-3 .
- Lee KT, Sohn IC, Kim DH, et al. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. Arch Pharm Res 2000;23:461-6.
- Yu Z, Zhang G, Zhao H. [Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function]. Zhong Yao Cai 1997;20:468-9.
- Hsu FL, Liu IM, Kuo DH, et al. Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. J Nat Prod 2003;66:788-92. PubMed
- Chiang HM, Fang SH, Wen KC, et al. Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats. Toxicol Appl Pharmacol 2005;209:263-8.
- Zheng, J., Chen, B., Jiang, B., Zeng, L., Tang, Z. R., Fan, L., and Zhou, H. H. The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo. Arch Pharm Res 2010;33(2):243-246. PubMed
- Hsu, H. H., Chang, C. K., Su, H. C., Liu, I. M., and Cheng, J. T. Stimulatory effect of puerarin on alpha1A-adrenoceptor to increase glucose uptake into cultured C2C12 cells of mice. Planta Med 2002;68(11):999-1003.
- Zheng, G., Zhang, X., Zheng, J., Meng, Q., and Zheng, D. [Estrogen-like effects of puerarin and total isoflavones from Pueraria lobata]. Zhong.Yao Cai. 2002;25(8):566-568.
- Qi, B. L. and Qi, B. M. [Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats]. Zhongguo Zhong.Yao Za Zhi. 2002;27(11):850-852.
- Akita, H., Sowa, J., Makiura, M., Akamatsu, H., and Matsunaga, K. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48(6):348-349. PubMed
- Manonai, J., Chittacharoen, A., Theppisai, U., and Theppisai, H. Effect of Pueraria mirifica on vaginal health. Menopause. 2007;14(5):919-924. PubMed
- Chandeying, V. and Sangthawan, M. Efficacy comparison of Pueraria mirifica (PM) against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of climacteric symptoms in perimenopausal women: phase III study. J M
- Virojchaiwong, P., Suvithayasiri, V., and Itharat, A. Comparison of Pueraria mirifica 25 and 50 mg for menopausal symptoms. Arch.Gynecol.Obstet. 2011;284(2):411-419. PubMed
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- Kim HJ, Kim H, Ahn JH, Suk JH. Liver injury induced by herbal extracts containing mistletoe and kudzu. J Altern Complement Med 2015;21(3):180-5. PubMed
- Santosh N, Mohan K, Royana S, Yamini TB. Hepatotoxicity of tubers of Indian Kudzu (Pueraria tuberosa) in rats. Food Chem Toxicol. 2010 Apr;48(4):1066-71. PubMed
- Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol. 2015 Jan-Feb;14(1):7-19. DOI
- Wang D, Qiu L, Wu X, Wei H, Xu F. Evaluation of kudzu root extract-induced hepatotoxicity. J Ethnopharmacol. 2015 Dec 24;176:321-6. PubMed
- Warinsiriruk P, Tantitham C, Cherdshewasart W, Shobeiri SA, Manonai J. Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause. Maturitas 2022;160:4-10. PubMed
Peony 15 references
- Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
- Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
- Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
- Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
- Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
- Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
- Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
- Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
- Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
- Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
- Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
- Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
- Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
- Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
- Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i
Baikal Skullcap 34 references
- Huang KC. The pharmacology of Chinese herbs. 2nd ed. New York, NY: CRC Press LLC. 1999;385-6, 400-1.
- Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. Planta Med 2000;66:91-3.
- Liao JF, Wang HH, Chen MC, et al. Benzodiazepine binding site-interactive flavones from Scutellaria baicalensis root. Planta Med 1998;64:571-2.
- Nishioka T, Kawabata J, Aoyama Y. Baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis. J Nat Prod 1998;61:1413-5.
- Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
- Fan L, Zhang W, Guo D, et al. The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1. Clin Pharmacol Ther 2007;83:471-6. PubMed
- Chen C, Mireles RJ, Campbell SD, et al. Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab Dispos 2005;33:537-46. PubMed
- Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther 2007;82:726-33. PubMed
- Konig J, Seithel A, Gradhand U, Fromm MF. Pharmacogenomics of human OATP transporters. Naunyn-Schmiedeberg Arch Pharmacol 2006;372:432-43. PubMed
- Chalasani N, Vuppalanchi R, Navarro V, et al. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Ann Intern Med 2012;156:857-60. PubMed
- Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Ann Intern Med 2012;156:894-5. PubMed
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- Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. Pl PubMed
- Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. J Med Chem 10-21-2004;47(22):5555-5566. PubMed
- Huang, Y., Tsang, S. Y., Yao, X., and Chen, Z. Y. Biological properties of baicalein in cardiovascular system. Curr Drug Targets.Cardiovasc.Haematol.Disord 2005;5(2):177-184. PubMed
- Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. Ann N Y Acad Sci 2007;1095:521-526. PubMed
- Waisundara, V. Y., Hsu, A., Huang, D., and Tan, B. K. Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats. Am J Chin Med 2008;36(3):517-540.
- Go, W. J., Ryu, J. H., Qiang, F., and Han, H. K. Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. J Nat Prod 2009;72(9):1616-1619. PubMed
- Linnebur, S. A., Rapacchietta, O. C., and Vejar, M. Hepatotoxicity associated with chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. Pharmacotherapy 2010;30(7):750, 258e-750, 262e. PubMed
- Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. PubMed
- Chang, H. H., Yi, P. L., Cheng, C. H., Lu, C. Y., Hsiao, Y. T., Tsai, Y. F., Li, C. L., and Chang, F. C. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. J Ethnopharmacol. 5- PubMed
- Li, T., Li, N., Guo, Q., Ji, H., Zhao, D., Xie, S., Li, X., Qiu, Z., Han, D., Chen, X., and You, Q. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. Eur J Drug Metab Pharmacokinet. 6-29-2011; PubMed
- Lin H, Zhou J, Lin K, et al. Efficacy of Scutellaria baicalensis for the treatment of hand, foot, and mouth disease associated with encephalitis in patients infected with EV71: a multicenter, retrospective analysis. Biomed Res Int 2016;2016:5697571.
- Papafragkakis C, Ona MA, Reddy M, Anand S. Acute hepatitis after ingestion of a preparation of Chinese skullcap and black catechu for joint pain. Case Reports Heptal 2016;2016:4356749. PubMed
- Kim M, Lee BC. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. Evid Based Complement Alternat Med. 2019;2019:3239649.
- Braude MR, Bassily R. Drug-induced liver injury secondary to Scutellaria baicalensis (Chinese skullcap). Intern Med J. 2019;49(4):544-546. PubMed
- Shin NR, Gu N, Choi HS, Kim H. Combined effects of Scutellaria baicalensis with metformin on glucose tolerance of patients with type 2 diabetes via gut microbiota modulation. Am J Physiol Endocrinol Metab. 2020;318(1):E52-E61.
- Li WJ, Bao J, Zheng DC, et al. Treatments of Peyronie's disease with Scutellaria baicalensis and surgery according to the disease course: a single-center retrospective study of 261 patients. Ann Palliat Med. 2021 Mar;10(3):2979-2989. PubMed
- Adam T, Bursztejn AC, Schmutz JL. Facial eczema from a sunscreen: Scutellaria baicalensis, a novel allergen beginning to attract attention. Contact Dermatitis. 2020 Apr;82(4):253-254.
- Luna-Bastante L, Gatica-Ortega ME, Pastor-Nieto MA, et al. Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics. Contact Dermatitis. 2020 May;82(5):307-309.
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Magnolia 9 references
- Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
- Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
- Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
- Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
- Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
- Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
- Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.
Siberian Cocklebur 4 references
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