No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Silica Ingredients & Drug Interactions

by Zemvelo

Silica label
See full label image
Liquid Category: Mineral
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Silica against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Silica is a dietary supplement by Zemvelo with 1 active ingredient. Its ingredients are commonly taken for hair, skin, and nail health, bone health and osteoporosis, joint and connective tissue support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Silica by Zemvelo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Zemvelo Silica is a liquid supplement containing one active ingredient: silica (also called silicon). Silica is a mineral that plays a role in bone structure, connective tissue, and hair and nail strength.

The product also contains inactive ingredients including reverse osmosis water, fulvic acid, citric acid, and sorbic acid, which serve as a base, pH buffer, and preservative.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: collagen, hair, skin, nails, bones, joints.
  • We looked for evidence on: Aging skin, Osteoporosis, Androgenic alopecia, Cardiovascular disease (CVD), connective tissue health, tendon and ligament strength — and 1 related terms.
  • The strongest evidence on file: Silicon is rated "Possibly Effective" for Osteoporosis (Natural Medicines).
  • Also on file: Silicon is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Androgenic alopecia, Cardiovascular disease (CVD).

The evidence for silica is mixed. For osteoporosis, it's rated possibly effective — meaning there's some promising evidence, but we'd need more research to be sure.

For hair loss (androgenic alopecia) and gum disease around dental implants (peri-implantitis), the evidence isn't established enough for us to rate it. If bone or hair health is your main reason for considering this supplement, talk with your doctor about whether silica fits your plan.

The evidence, ingredient by ingredient Silicon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Silica from food and typical supplement doses is generally well tolerated, though long-term safety at higher doses hasn't been well studied. The safety data advises against use during pregnancy and while breastfeeding, so if you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this product.

Note: the serious adverse effects listed in our data relate to inhaled crystalline silica dust in occupational settings (like mining or construction), not to silica taken by mouth in supplement form.

Side effects, ingredient by ingredient Silicon

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for silica. That said, it's always smart to mention any supplement you're adding to your doctor or pharmacist, especially if you have kidney problems or are on dialysis, since the adverse effects section notes a link between high silicon levels and liver disease in dialysis patients.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Zemvelo Silica may be worth considering if you're looking for support for bone health, though the evidence is still developing. It's not suitable during pregnancy or while breastfeeding.

Since no interactions with medications are documented for this ingredient, it's generally compatible with most drug regimens — but confirm with your own doctor or pharmacist, especially if you take multiple medications or have kidney disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Silica, straight from the product label.

Brand Zemvelo
Barcode (UPC) 891663002407
Net contents 8.1 Fluid Ounce(s); 240 mL
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 249810
Product type Mineral
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Silica by Zemvelo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
5 mL
Servings per container
48
UPC/BARCODE
891663002407
IngredientAmount% DV
Silica125 mg--

Other ingredients: reverse osmosis Water, CHD-FA Fulvic Acid, Citric Acid, non-GMO Sorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Aids in collagen production Supports strong hair, skin, & nails Provides joint, tendon, ligament, & cartilage support Supports bone health & formation Supports healthy blood vessels & arteries

Vegan

Gluten-free Non GMO

Third party tested

Formula

+CHD-Fulvic acid for enhanced absorption

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Vegan

Manufactured in the U.S.A. cGMP

Suggested/Recommended/Usage/Directions

Directions: Adults: Place 1 teaspoon (5mL) into 6-8 oz of water or juice as maintenance. Use more if needed or as recommended by your healthcare professional.

Shake well before use.

For freshness, keep refrigerated after opening

Precautions

Children under 4: Consult your physician.

Do not use if temper evident seal is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Silica by Zemvelo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Silica label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Silica by Zemvelo

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container48 Amounts shown are per serving.

Silica

No known
interactions
125 mg per serving Form: Orthosilicic Acid

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...

Silica monograph & interactions

Other (inactive) ingredients: Reverse osmosis Water, CHD-FA Fulvic Acid, Citric Acid, Non-GMO Sorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Silica by Zemvelo Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Silica. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Silica, from the product label.

Zemvelo

See all Zemvelo products
Name
Zemvelo by MINERALIFE "Love & Gratitude"
Street Address
1435 Woolsey Hts
City
Colorado Springs
State
CO
ZipCode
80915
Phone Number
8003031376
Web Address
zemvelo.com
Pharmacist Counseling Corner

Silica by Zemvelo: Common Questions

Does Silica by Zemvelo interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Silica. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Silica contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is silica safe to take long-term?
Silica from food and typical supplement doses is generally well tolerated, but the safety data shows that high-dose or long-term safety hasn't been well studied. If you're planning to take this regularly, it's a good idea to mention it to your doctor.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against silica supplements during pregnancy and while breastfeeding because there isn't enough reliable safety data. Talk with your doctor or pharmacist about alternatives if either applies to you.
What does silica do?
Silica is a mineral involved in bone structure and connective tissue strength, and it plays a role in hair and nail health. Research shows it's possibly effective for osteoporosis, but the evidence for hair loss and gum disease is still developing.
Does silica interact with my medications?
No interactions are documented in our data for silica. That said, it's always worth mentioning any new supplement to your own doctor or pharmacist to make sure it fits with your specific medications and health situation.
Is this the same as the silica that causes lung disease?
No — the lung disease risk comes from inhaling crystalline silica dust in occupational settings like mining or construction, not from silica taken by mouth in supplement form. Oral silica from food and supplements at normal doses is not associated with those risks.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Silica is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Silica label
Go deeper

The Full Monographs Behind Silica’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Silicon

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for hair, skin, nail, and bone health. Some s...

Read the full Silicon monograph →
Sources

Sources & How We Checked

Silica's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Silicon 19 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
  3. Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
  4. Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
  5. Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
  6. Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
  7. Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
  8. Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
  9. McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
  10. Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
  11. Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
  12. Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
  13. Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
  14. Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
  15. McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
  16. Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
  17. Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
  18. Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
  19. Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed

See these in context on the Silicon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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