Sleep Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sleep against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sleep is a dietary supplement by Warrior Strong Wellness with 2 active ingredients. Its ingredients are commonly taken for anxiety and stress, relaxation and calm, sleep support.Based on those ingredients, 565 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sleep by Warrior Strong Wellness
Ask about any prescription or over-the-counter medication and we check it for interactions with Sleep by Warrior Strong Wellness — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sleep by Warrior Strong Wellness
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Warrior Strong Wellness Sleep contains 2 active ingredients: L-theanine and apigenin. L-theanine is an amino acid that may help with relaxation and cognitive function, while apigenin is a plant compound.
The capsule also contains three inactive ingredients—hypromellose, rice flour, and stearate—which are fillers and binders that give the supplement its form.
Does it work?
Not established
For L-theanine, the evidence supports it as possibly effective for cognitive function. For age-related cognitive decline, Alzheimer disease, generalized anxiety disorder, obsessive-compulsive disorder, and cancer, we don't have enough reliable evidence to rate whether it works.
We hold no effectiveness data for apigenin.
How safe is it?
Well-documented data
L-theanine is generally well tolerated in healthy adults when used short-term, but long-term safety hasn't been well studied. The most common side effects are headaches and drowsiness; some people also report longer sleep duration and more vivid dreams.
One case of facial tics was reported in a child, but it wasn't clearly tied to the supplement. There isn't enough safety data on L-theanine in pregnancy or while breastfeeding, so it's best to avoid it during those times.
We hold no safety data for apigenin.
Meds to double-check
Moderate interaction found
Before you take this, check with your pharmacist if you're on blood pressure medications—L-theanine could potentiate their effect and lower your pressure too much. Also flag any sedatives, sleep aids, pain relievers, or serotonergic drugs like certain antidepressants.
We could not check apigenin against our database, so mention all your medications to be thorough.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This sleep formula may help with relaxation, but it's important to check it against any blood pressure or neurological medications you take. If you're pregnant, breastfeeding, or taking multiple prescriptions, talk to your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sleep, straight from the product label.
| Brand | Warrior Strong Wellness |
|---|---|
| Barcode (UPC) | X003W1SOJ9 |
| Net contents | 60 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 321108 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sleep by Warrior Strong Wellness, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Theanine | 200 mg | -- |
| Apigenin | 50 mg | -- |
Other ingredients: Hypromellose, Rice Flour, Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
L-Theanine is an amino acid commonly found in tea leaves, particularly in green tea (Camellia sinensis). May have a calming and relaxing effect on the mind and body. Apigenin is a powerful bioflavonoid found in chamomile tea and an antioxidant compound found in many different plants, herbs, fruit and vegetables. May improve sleep quality.
L-Theanine & Apigenin
General Statements
St. Baldrick's Foundation Conquer Childhood Cancers A portion of the proceeds will be donated to childhood cancer research
Save 15% on www.warriorstrongwellness.com
Warrior Strong Wellness has been providing quality products since 2017
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Caution: Consult your doctor Before using this product, if you are taking any medications. Especially, if you are taking SSRIs, hormones or blood thinning type medications. Interactions: L-Theanine may interact with certain medications, including blood pressure medications, stimulants, and medications that affect neurotransmitter levels. Consult with your healthcare provider to ensure there are no potential interactions with your current medications. Do not take this product if you are pregnant or nursing or under the age of 18.
Allergens: If you have known allergies or sensitivities to amino acids, tea, or tea-related products, your should exercise caution when taking L-Theanine.
Do not take this product if you are pregnant or nursing or under the age of 18. Keep out of reach of children.
Discontinue use and consult a doctor immediately if any adverse reactions occur. Do not take this product, L-Theanine and Apigenin and operate any heavy machinery or drive until you know how it affects you. It is best to take it before bedtime. Do not exceed more than 4 capsules per day.
Suggested/Recommended/Usage/Directions
Recommended dosage 1 capsule in the evening before bed.
Suggested use: Take 1 capsule per day in the evening before bedtime, as a dietary supplement.
Storage
Storage: Store in a cool, dark, dry place.
Formulation
Natural rest Restful sleep Calm mind & body Relaxation support
Tested in an ISO Certified Lab
Soy free GMO free Dairy free Gluten free
Vegan
Seals/Symbols
Made in a GMP Certified Facility Made in a FDA Registered Facility
Manufactured in the US
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sleep by Warrior Strong Wellness label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sleep by Warrior Strong Wellness
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Theanine
Interacts with565 drugs
Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...
L-Theanine monograph & interactionsApigenin
Other (inactive) ingredients: Hypromellose, Rice Flour, Stearate. These complete the product’s ingredient list but are not active constituents.
Sleep by Warrior Strong Wellness Drug Interactions
HelloPharmacist Interaction Report
Warrior Strong Wellness Sleep contains L-theanine, which has documented interactions with several medication types.
The most serious concern is with blood pressure medications (antihypertensives): L-theanine may lower blood pressure on its own, and combining it with your blood pressure drug could push your pressure too low.
Read the full breakdown — every affected drug type, severity by severity
L-theanine also has minor interactions with drugs that depress your central nervous system (CNS depressants)—including sedatives, sleep aids, and some pain relievers. While the concern is mainly theoretical, there's a possibility of extra drowsiness or sedation.
It also has a minor interaction with serotonergic drugs (medications that affect serotonin, like some antidepressants), though no cases of serotonin syndrome have been reported with L-theanine.
We could not check apigenin, the second ingredient, against our interaction database. Altogether, these interactions span 563 individual medications.
Use the medication checker on this page to look up your specific prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sleep?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sleep interact with 565 drugs. Click any drug to see the details.
1 of the 2 ingredients in Sleep interact with drugs. Each result below shows which ingredient is responsible. L-Theanine
AcepromazineAtravet
How Acepromazine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acepromazine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs, Cns Depressants Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants, Serotonergic Drugs Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineCns Depressants Minor
Interaction Summary
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full L-theanine + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Sleep — through 1 ingredient. Tap an ingredient for the detail:
L-theanineSerotonergic Drugs Minor
Interaction Summary
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting.
Read the full L-theanine + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sleep with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Theanine
Antihypertensive Drugs
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.
Cns Depressants
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.
Serotonergic Drugs
Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.
Brand information
Manufacturer and brand details for Sleep, from the product label.
Warrior Strong Wellness
See all Warrior Strong Wellness products- Name
- Warrior Strong Enterprises, LLC
- Street Address
- 9850 S Maryland Parkway Ste A-5-569
- City
- Las Vegas
- State
- NV
- ZipCode
- 89183
- Web Address
- www.warriorstrongwellness.com
Sleep by Warrior Strong Wellness: Common Questions
Does Sleep by Warrior Strong Wellness interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects of L-theanine?
Does L-theanine actually improve sleep or cognitive function?
What is apigenin, and why can't you check it for interactions?
Is L-theanine safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sleep is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sleep’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sleep's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Theanine 6 references
- Yokogoshi H, Kobayashi M. Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. Life Sci 1998;62:1065-8.
- Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., and Scholey, A. B. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol.Psychol. 2008;77(2):113-122. PubMed
- Yokogoshi, H., Kato, Y., Sagesaka, Y. M., Takihara-Matsuura, T., Kakuda, T., and Takeuchi, N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci.Biotechnol.Biochem. 1995;59(4):615-618. PubMed
- Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-
- Hidese S, Ota M, Wakabayashi C, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr 2017;29(2):72-9.
- Tsuchiya T, Honda H, Oikawa M, et al. Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients. Int J Clin Oncol 2016;21(6):1085-90. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC