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Dietary supplement

Slippery Elm Bark Extract Powder 750 mg Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Slippery Elm Bark Extract Powder 750 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: slippery elm bark extract at 750 mg per serving. Slippery elm inner bark is a traditional botanical used to coat and soothe the digestive tract, and it gets its name from the slick mucilage it produces.

The powder also includes dextrin as an inactive ingredient (a filler or flow agent).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Slippery Elm product and its label doesn't state a use — see Slippery Elm's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have isn't established yet for slippery elm's use in any of the conditions it's marketed for — cancer, constipation, cough, diarrhea, and inflammatory bowel disease (IBD). The data available rates all of these as insufficient reliable evidence to rate.

That doesn't mean it doesn't work; it means rigorous clinical trials haven't confirmed its benefit for any of these uses in our current data.

The evidence, ingredient by ingredient Slippery Elm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited, so we don't know everything about long-term safety. If you apply it to your skin, it can cause contact dermatitis (a rash at the site of contact).

The pollen and an oily substance in the bark called oleoresin can trigger allergic reactions, including hives. Pregnant and breastfeeding people should be cautious — there isn't enough reliable safety data to know whether it's safe, so talk with your doctor or pharmacist before taking it during pregnancy or while nursing.

Side effects, ingredient by ingredient Slippery Elm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Any oral medications (pills, capsules, liquids taken by mouth) are affected — the mucilage in slippery elm can slow their absorption and lower their blood levels. This is a Moderate-severity interaction, so don't skip the interaction checker on this page.

Space this supplement at least two hours away from your drugs if you do take it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Slippery elm may appeal to you if you're looking for a traditional approach to digestive comfort, but the evidence of benefit isn't established yet. The main thing to watch is that it may interfere with how your body absorbs oral medications — and that affects thousands of drugs.

Check your exact medications with our tool, space out doses carefully, and talk to your pharmacist to make sure it's okay for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slippery Elm Bark Extract Powder 750 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X001A3D7R5
Net contents 500 Gram(s); 17.6 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330740
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
750 Milligram(s)
Maximum serving Sizes:
750 Milligram(s)
Servings per container
667
UPC/BARCODE
X001A3D7R5
IngredientAmount% DV
Slippery Elm Bark Extract750 mg--

Other ingredients: Dextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Slippery Elm Bark Extract Powder 750 mg per serving

Brand IP Statement(s)

BulkSupplements.com Clean & Pure Bulk Supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 750 mg (about 1/3 tsp) once daily, or as directed by a physician.

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

General Statements

Use an accurate milligram scale. New

See for yourself

Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size750 Milligram(s) Dosage formPowder Servings per container667 Amounts shown are per serving.

Slippery Elm Bark Extract

Interacts with
2,022 drugs
750 mg per serving Form: Ulmus rubra Bark Extract

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...

Slippery Elm Bark Extract monograph & interactions

Other (inactive) ingredients: Dextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Slippery Elm Bark Extract Powder 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,022Drugs
2,022 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Slippery Elm Bark Extract Powder 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm Bark Extract1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Slippery Elm Bark Extract Powder 750 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com: Common Questions

Does Slippery Elm Bark Extract Powder 750 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Slippery Elm Bark Extract Powder 750 mg has a known interaction with 2,022 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slippery Elm Bark Extract Powder 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will slippery elm help with my digestive symptoms?
The evidence isn't there yet to say for sure. Our data rates its use for constipation, diarrhea, and inflammatory bowel disease as insufficient reliable evidence — meaning clinical trials haven't confirmed a benefit. It's been used traditionally for these, but we can't promise it'll work for you based on what we know.
Can I take this while I'm pregnant or breastfeeding?
There isn't enough reliable safety data to know whether it's safe during pregnancy or breastfeeding. Talk with your doctor or pharmacist before you take it — they can weigh the potential risks and benefits for your specific situation.
What's in this powder besides the slippery elm?
Just dextrin, which is an inactive ingredient used as a filler. There are no other active ingredients.
Can slippery elm cause an allergic reaction?
Yes — the pollen and an oily component in the bark can trigger hives, rash, and contact dermatitis in sensitive people. If you're allergic to elm trees or have a history of skin sensitivity, be cautious and test a small amount first.
How far apart should I take this from my medications?
At least two hours apart is ideal, since slippery elm may slow how your body absorbs oral drugs. But check your exact medications using the tool on this page, and talk to your pharmacist about the best timing for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slippery Elm Bark Extract Powder 750 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slippery Elm Bark Extract Powder 750 mg label
Go deeper

The Full Monographs Behind Slippery Elm Bark Extract Powder 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Slippery Elm Bark Extract Powder 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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