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Dietary supplement

Sprouted Broccoli Seed 400 mg Ingredients & Drug Interactions

by Swanson GreenFoods Formulas

Sprouted Broccoli Seed 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sprouted Broccoli Seed 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sprouted Broccoli Seed 400 mg is a dietary supplement by Swanson GreenFoods Formulas with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic sprouted Broccoli. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic sprouted broccoli in a 400 mg capsule. Inactive ingredients include pullulan (a plant-based capsule material), organic rice concentrate and extract, organic sunflower oil, and de-oiled sunflower lecithin — all there to hold the capsule together and help with absorption.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Broccoli's overall clinical evidence instead.

Moderate

Some clinical evidence supports Broccoli for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Natural Medicines).

Broccoli appears to be possibly effective for colorectal cancer prevention based on the data we hold. For bladder cancer, breast cancer, fibromyalgia, and gastric cancer, the evidence isn't established enough to rate it either way — there's just not enough reliable research yet to say whether it works.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is generally well tolerated by most people. However, concentrated broccoli supplements like this one are less studied than the whole vegetable, and the facts note that safety data for concentrated extracts isn't well established yet.

Some people report loose stools, diarrhea, abdominal pain, or cramping after taking broccoli seed and sprout extracts, especially at higher doses. Allergic contact dermatitis from broccoli has also been reported when applied to skin.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medications processed by CYP2A6 (Moderate severity) or CYP1A2 (Moderate severity) enzymes with your doctor or pharmacist — this includes smoking-cessation drugs, some cancer therapies, and other prescription medications. The broccoli in this supplement can speed up how your body clears these drugs, potentially weakening them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take medications that are processed through CYP1A2 or CYP2A6 enzymes — including certain drugs for smoking cessation, some cancer treatments, or specific pain relievers — you'll need to check with your doctor or pharmacist before using this. Pregnancy and lactation data shows it's likely safe, but the evidence base for concentrated supplements is thinner than for eating broccoli as a vegetable.

Talk it over with your own healthcare provider if you have questions about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sprouted Broccoli Seed 400 mg, straight from the product label.

Brand Swanson GreenFoods Formulas
Barcode (UPC) 087614060835
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 176236
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614060835
IngredientAmount% DV
organic sprouted Broccoli400 mg--

Other ingredients: Pullulan, organic Rice concentrate, organic Rice extract, organic Sunflower Oil, de-oiled Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Phytonutrient-rich green foods

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Formula

Made with organic Broccoli seed

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

V Vegetarian formula Guaranteed purity & potency

Formulation

V Vegetarian formula

Certified organic by Minnesota Crop Improvement Association (MCIA), St. Paul, MN 55108.

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Suggested Use: As a dietary supplement, take one veggie capsule one to two times per day with water.

General

SWR083 Rev 0 07 21 17

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sprouted Broccoli Seed 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Organic sprouted Broccoli

Interacts with
187 drugs
400 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Organic sprouted Broccoli monograph & interactions

Other (inactive) ingredients: Pullulan, Organic Rice concentrate, Organic Rice extract, Organic Sunflower Oil, De-oiled Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas Drug Interactions

Want to check YOUR meds against Sprouted Broccoli Seed 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

organic sprouted Broccoli 187

Individual Drug Interactions

The ingredients in Sprouted Broccoli Seed 400 mg interact with 187 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sprouted Broccoli Seed 400 mg interact with drugs. Each result below shows which ingredient is responsible. organic sprouted Broccoli

Each ingredient & the kinds of drugs it affects

For each ingredient in Sprouted Broccoli Seed 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic sprouted Broccoli2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
organic sprouted Broccoli full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sprouted Broccoli Seed 400 mg, from the product label.

Swanson GreenFoods Formulas

See all Swanson GreenFoods Formulas products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas: Common Questions

Does Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas interact with any medications?
Yes. Based on its ingredients, Sprouted Broccoli Seed 400 mg has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sprouted Broccoli Seed 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me the same dose of broccoli as eating fresh broccoli?
No. This is a 400 mg concentrated supplement, not the same as eating a whole cup of fresh broccoli. The research showing strong enzyme effects used 500 grams (over a pound) of fresh broccoli daily, so the dose and form here are quite different. If you're taking medications affected by broccoli's enzyme-inducing compounds, the supplement dose may still matter — that's why checking with your doctor or pharmacist is important.
Is this safe during pregnancy or breastfeeding?
According to the data we hold, broccoli in pregnancy and lactation is rated likely safe. That said, most of the safety research is on eating broccoli as food, not on concentrated supplements, so there's less evidence for this form specifically. Talk with your doctor or pharmacist about whether this particular supplement is right for you during pregnancy or while breastfeeding.
Can this help prevent cancer?
Broccoli is possibly effective for colorectal cancer based on the evidence we hold. For bladder, breast, and gastric cancers, the research isn't strong enough yet to say whether it works. If you're interested in cancer prevention, have a conversation with your doctor about what the science currently supports.
What side effects might I experience?
Some people experience loose stools, diarrhea, abdominal pain, or cramping after taking broccoli seed and sprout extracts, especially at higher doses. These are usually digestive issues. Allergic skin reactions (contact dermatitis) have been reported with broccoli, though that's less common with supplements taken by mouth.
Why does this supplement interact with so many medications?
Broccoli contains glucosinolates — compounds that rev up your liver's CYP1A2 and CYP2A6 enzymes, which break down many different medications. When these enzymes work faster, they clear drugs from your system more quickly, which can lower drug levels and reduce their effectiveness. That's why 187 different medications are potentially affected — not because broccoli is toxic, but because it changes how your liver processes a wide range of prescriptions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sprouted Broccoli Seed 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sprouted Broccoli Seed 400 mg label
Go deeper

The Full Monographs Behind Sprouted Broccoli Seed 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Sprouted Broccoli Seed 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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