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Dietary supplement

Sprouted Broccoli Seed 400 mg Ingredients & Drug Interactions

by Swanson GreenFoods Formulas

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sprouted Broccoli Seed 400 mg is a dietary supplement by Swanson GreenFoods Formulas with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic sprouted Broccoli. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 400 mg of organic sprouted broccoli. Sprouted broccoli is broccoli seed that has been allowed to germinate, concentrating its nutrients.

The remaining ingredients are inactive — pullulan (a plant-based capsule material), organic rice concentrate, organic rice extract, organic sunflower oil, and de-oiled sunflower lecithin — used to fill the capsule and improve absorption.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Phytonutrient-rich green foods.
  • We looked for evidence on: Bladder cancer, Breast cancer, Colorectal cancer, Gastric cancer, Prostate cancer, Hypercholesterolemia — and 4 related terms.
  • The strongest evidence on file: Broccoli is rated "Possibly Effective" for Colorectal cancer (Natural Medicines).
  • Also on file: Broccoli is rated "Insufficient Reliable Evidence To Rate" for Bladder cancer, Breast cancer, Gastric cancer, Hypercholesterolemia, and more.

Broccoli is possibly effective for reducing colorectal cancer risk. For bladder cancer, breast cancer, fibromyalgia, and gastric cancer, the evidence in our data is insufficient — we don't have enough reliable evidence to say whether it works or doesn't.

If you're considering this supplement for any of these conditions, talk with your doctor or pharmacist about what the research actually supports.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as food is well tolerated in normal amounts, but concentrated supplements like this one are less studied. The facts note caution with concentrated extracts unless your doctor approves.

Some people taking broccoli seed or sprout extracts have reported loose stools, diarrhea, stomach pain, and cramping, especially at higher doses. Topically, allergic reactions causing contact dermatitis have occurred, though that's less relevant to a capsule.

Broccoli is rated Likely Safe in pregnancy and lactation.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check any medications that are broken down by CYP1A2 or CYP2A6 liver enzymes — broccoli can reduce how well they work. Use the medication checker on this page to verify your exact prescriptions, as these two enzyme groups affect a broad range of drugs.

Altogether, these interactions span 187 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is a concentrated form of broccoli, and while broccoli as food is fine, concentrated extracts are less well studied. The main concern is that it may make certain medications less effective by speeding up how your liver processes them.

If you take any prescription drugs — especially those metabolized by CYP1A2 or CYP2A6 enzymes — check them against the interaction tool before starting. Talk with your pharmacist about whether this product is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sprouted Broccoli Seed 400 mg, straight from the product label.

Brand Swanson GreenFoods Formulas
Barcode (UPC) 087614060835
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 176236
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614060835
IngredientAmount% DV
organic sprouted Broccoli400 mg--

Other ingredients: Pullulan, organic Rice concentrate, organic Rice extract, organic Sunflower Oil, de-oiled Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Phytonutrient-rich green foods

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Formula

Made with organic Broccoli seed

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

V Vegetarian formula Guaranteed purity & potency

Formulation

V Vegetarian formula

Certified organic by Minnesota Crop Improvement Association (MCIA), St. Paul, MN 55108.

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Suggested Use: As a dietary supplement, take one veggie capsule one to two times per day with water.

General

SWR083 Rev 0 07 21 17

See for yourself

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Organic sprouted Broccoli

Interacts with
187 drugs
400 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Organic sprouted Broccoli monograph & interactions

Other (inactive) ingredients: Pullulan, Organic Rice concentrate, Organic Rice extract, Organic Sunflower Oil, De-oiled Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas Drug Interactions

Want to check YOUR meds against Sprouted Broccoli Seed 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sprouted Broccoli Seed 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic sprouted Broccoli2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Sprouted Broccoli Seed 400 mg, from the product label.

Swanson GreenFoods Formulas

See all Swanson GreenFoods Formulas products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas: Common Questions

Does Sprouted Broccoli Seed 400 mg by Swanson GreenFoods Formulas interact with any medications?
Yes. Based on its ingredients, Sprouted Broccoli Seed 400 mg has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sprouted Broccoli Seed 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant or breastfeeding?
Broccoli is rated Likely Safe in pregnancy and lactation. That said, concentrated supplements are less studied than broccoli as food. If you're pregnant or nursing, it's worth checking with your doctor or pharmacist for personalized advice.
Can I take this if I'm on medication?
It depends on what you take. Broccoli can speed up how your liver processes certain drugs — particularly those broken down by two liver enzymes called CYP1A2 and CYP2A6 — which might make them less effective. Use the medication checker on this page to see if any of your prescriptions are affected.
What side effects might I experience?
Some people report loose stools, diarrhea, stomach pain, and cramping from broccoli seed extracts, especially at higher doses. Start with the recommended amount and see how you feel. If you have digestive issues, talk to your pharmacist.
Does this really help prevent cancer?
The evidence is limited. Broccoli is possibly effective for colorectal cancer risk. For bladder cancer, breast cancer, gastric cancer, and fibromyalgia, we don't have enough reliable evidence to say whether it works. Your doctor can discuss whether it's worth trying alongside your regular care.
Is this the same as eating broccoli?
No. This is a concentrated extract of sprouted broccoli seed. Broccoli as food is safe and well tolerated in normal amounts, but concentrated supplements are less studied. That's why caution is recommended unless your doctor approves it.
What are the inactive ingredients?
The capsule is made of pullulan, a plant-based material. The other inactive ingredients are organic rice concentrate, organic rice extract, organic sunflower oil, and de-oiled sunflower lecithin — they help fill and stabilize the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sprouted Broccoli Seed 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sprouted Broccoli Seed 400 mg label
Go deeper

The Full Monographs Behind Sprouted Broccoli Seed 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sprouted Broccoli Seed 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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