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Dietary supplement

Klamath Blue-Green Algae 500 mg Ingredients & Drug Interactions

by Swanson GreenFoods Formulas

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Klamath Blue-Green Algae 500 mg is a dietary supplement by Swanson GreenFoods Formulas with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic, wild-harvest Blue-Green Algae. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic, wild-harvest blue-green algae at 500 mg per tablet. It also includes two inactive ingredients—maltodextrin and silica—which serve as binders and flow agents in the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Blue-green Algae's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Phytonutrient-rich green foods general nutrition.
  • We looked for evidence on: Malnutrition, General wellness, Nutritional supplementation.
  • The closest evidence on file: Blue-green Algae is rated "Insufficient Reliable Evidence To Rate" for Malnutrition (Natural Medicines).

The evidence for blue-green algae is mixed and limited. It's rated possibly effective for high blood pressure based on available research.

For other uses listed—acne, hay fever (allergic rhinitis), iron-deficiency anemia, and arsenic poisoning—the evidence isn't established enough to rate. The data we hold doesn't support or refute effectiveness for these conditions.

The evidence, ingredient by ingredient Blue-green Algae

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue-green algae are generally well tolerated orally, though a range of mild gastrointestinal side effects have been reported, including abdominal cramps, bloating, diarrhea, nausea, vomiting, flatulence, headache, dizziness, and fatigue. Allergic reactions are rare but possible—urticaria (hives) and itching have occurred, and one case of severe anaphylaxis (a life-threatening allergic reaction) was reported in a teenager within 6 hours of taking spirulina tablets.

A critical safety concern: quality varies widely between brands, and some products can be contaminated with toxins or heavy metals. The safety data available advises caution, and contamination risk is real.

Side effects, ingredient by ingredient Blue-green Algae

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blue-green Algae.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your pharmacist before starting if you take blood thinners or antiplatelet drugs (Moderate severity), immunosuppressive medications (Moderate severity), or diabetes drugs (Moderate severity). No other medication types are documented to interact with the ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you have high blood pressure and want to explore blue-green algae, talk with your pharmacist or doctor first—especially if you're on blood thinners, diabetes drugs, or immunosuppressants. Quality and contamination are serious concerns with this category of product.

Always check your exact medications against our interaction tool before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klamath Blue-Green Algae 500 mg, straight from the product label.

Brand Swanson GreenFoods Formulas
Barcode (UPC) 087614060583
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Jan 7, 2019
DSLD ID 184770
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
087614060583
IngredientAmount% DV
certified organic, wild-harvest Blue-Green Algae500 mg--

Other ingredients: Maltodextrin, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Phytonutrient-Rich Green Foods

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Formula

Made with Certified Organic Klamath Blue-Green Algae

Wild-harvested freshwater Algae

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one tablet one to two times per day, preferably on an empty stomach, with an 8-ounce glass of water.

General

SWR058 Rev 0 02 27 18

Formulation

Certified Organic by Minnesota Crop Improvement Association (MCIA), St. Paul, MN 55108.

See for yourself

Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

500 mg per serving Form: freshwater Algae

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...

Certified organic, wild-harvest Blue-Green Algae monograph & interactions

Other (inactive) ingredients: Maltodextrin, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas Drug Interactions

Want to check YOUR meds against Klamath Blue-Green Algae 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Klamath Blue-Green Algae 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic, wild-harvest Blue-Green Algae3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D
Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Klamath Blue-Green Algae 500 mg, from the product label.

Swanson GreenFoods Formulas

See all Swanson GreenFoods Formulas products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas: Common Questions

Does Klamath Blue-Green Algae 500 mg by Swanson GreenFoods Formulas interact with any medications?
Yes. Based on its ingredients, Klamath Blue-Green Algae 500 mg has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klamath Blue-Green Algae 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood thinners like warfarin?
Not without talking to your pharmacist first. Blue-green algae may increase bleeding risk when combined with blood thinners, though actual risk in real patients seems low. Your pharmacist needs to weigh the algae's potential benefit against your individual bleeding risk.
Will this help my hay fever or acne?
The evidence isn't established. We have insufficient reliable data to say whether blue-green algae works for allergic rhinitis (hay fever) or acne, so we can't recommend it for those uses based on the research we hold.
What are the most common side effects?
Gastrointestinal complaints—abdominal cramps, bloating, diarrhea, nausea, vomiting, and flatulence—are the most frequently reported. Headache, dizziness, and fatigue can occur too. Allergic reactions like hives or itching are rarer but do happen.
Is this product safe if I'm pregnant or breastfeeding?
There isn't enough safety data on file to say either way. Talk with your doctor or pharmacist about whether it's right for you during pregnancy or while nursing—it's an individual decision we can't make for you.
I'm on diabetes medication. Is this safe?
Blue-green algae can lower blood sugar, so theoretically taking it with diabetes drugs increases the risk of low blood sugar (hypoglycemia). Check with your pharmacist before starting, and if you do take it, monitor your blood sugar closely.
Should I worry about contamination?
Yes. Quality varies widely between brands, and some blue-green algae products are contaminated with toxins or heavy metals. Buy from a reputable manufacturer and ask your pharmacist for guidance on safe brands.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Klamath Blue-Green Algae 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klamath Blue-Green Algae 500 mg label
Go deeper

The Full Monographs Behind Klamath Blue-Green Algae 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Klamath Blue-Green Algae 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue-green Algae 22 references
  1. Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
  2. Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
  3. Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
  4. Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
  5. Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
  6. Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
  7. Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
  8. Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
  9. Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
  10. Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
  11. Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
  12. Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
  13. Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
  14. Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
  15. Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
  16. Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
  17. Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
  18. Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
  19. Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
  20. Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
  21. Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
  22. Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed

See these in context on the Blue-green Algae monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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