Standardized Olive Leaf Extract Ingredients & Drug Interactions
by 21st Century
What is this page for?
First and foremost: checking Standardized Olive Leaf Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Standardized Olive Leaf Extract is a dietary supplement by 21st Century with 1 active ingredient. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Standardized Olive Leaf Extract by 21st Century
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: olive leaf extract (a concentrated form derived from the leaves of the olive plant). Olives and olive oil as everyday foods are well tolerated, but this supplement is a more concentrated preparation and hasn't been studied as thoroughly.
The capsule also includes inactive ingredients — rice bran, oat fiber, vegetable cellulose, magnesium silicate, and magnesium stearate — which are fillers and binders that hold the supplement together.
Does it work?
Couldn't assess
The evidence supporting olive leaf extract for any of its claimed uses — osteoporosis, indigestion (dyspepsia), exercise-related respiratory infections, shingles, flu, or osteoarthritis — is insufficient to rate. The data we hold doesn't show it's been proven effective for these conditions.
That doesn't mean it doesn't work; it means the research backing it up isn't solid enough yet for us to say one way or the other.
How safe is it?
Well-documented data
Olive leaf extract appears to be generally well tolerated when taken by mouth. The most common side effects reported in trials were headache and stomach discomfort.
One person in one trial reported skin problems and acne, and people with seasonal allergies to olive tree pollen may react to this product. Because concentrated olive leaf supplements haven't been studied as extensively as olive oil or whole olives used as food, the safety profile isn't fully known.
The caution here is to get your doctor's approval before starting a concentrated supplement, especially if you have any underlying health concerns.
Meds to double-check
No known interactions
No interactions are documented in our data for the olive leaf extract in this product. Before you start, you can still use the medication search tool on this page to double-check your exact prescriptions, but there are no specific drug types flagged as a concern.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Olive leaf extract is generally well tolerated, but the evidence for what it actually does isn't established yet. If you're interested in trying it for one of the conditions listed, talk it over with your doctor or pharmacist first — they can help you decide whether it's a reasonable option for you and whether it fits with the rest of your health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Standardized Olive Leaf Extract, straight from the product label.
| Brand | 21st Century |
|---|---|
| Barcode (UPC) | 740985217160 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2012 |
| DSLD ID | 11492 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Standardized Olive Leaf Extract by 21st Century, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Olive Leaf Extract | 500 mg | -- |
Other ingredients: Rice Bran, Oat Fiber, Vegetable Cellulose, Magnesium Silicate, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take up to two (2) vegetarian capsules daily with meals for maximum daily results, or as directed by your healthcare provider.
Precautions
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Formulation
No added Sugar, Salt, Yeast, Preservatives or Artificial Flavors.
Formula
100% Vegetarian Formula
General Statements
The Natural Alternative for Improved Circulation and General Well Being*
Unconditionally guaranteed for purity, freshness and label potency.
HERBAL EXTRACT
21st Century's Extract (Olea europaea) standardized to 8% oleuropein is a valued nutritional discovery in support of the immune system.* For centuries the cultures of the Mediterranean have used olive daily in food preparations promoting good health and long life. 21st Century's standardized herbal extracts are thoroughly tested to assure specific levels of the important active ingredients are present for maximum benefit.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
21ST Century(R)...for a healthier future.
Storage
Store at room temperature.
Seals/Symbols
MADE IN USA
General
0505
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Standardized Olive Leaf Extract by 21st Century label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Standardized Olive Leaf Extract by 21st Century
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Olive Leaf Extract
No knowninteractions
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...
Olive Leaf Extract monograph & interactionsOther (inactive) ingredients: Rice Bran, Oat Fiber, Vegetable Cellulose, Magnesium Silicate, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Standardized Olive Leaf Extract by 21st Century Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Standardized Olive Leaf Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Standardized Olive Leaf Extract, from the product label.
21st Century
See all 21st Century products- Name
- 21st Century Healthcare, Inc.
- Street Address
- 2119 S. Wilson Street
- City
- Tempe
- State
- AZ
- ZipCode
- 85282
- Web Address
- www.21stcenturyvitamins.com
Standardized Olive Leaf Extract by 21st Century: Common Questions
Does Standardized Olive Leaf Extract by 21st Century interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with the flu or a cold?
What are the most common side effects?
Is this safe if I'm pregnant or breastfeeding?
How does this differ from olive oil I cook with?
Can I take this with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Standardized Olive Leaf Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Standardized Olive Leaf Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Standardized Olive Leaf Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Olive 2 references
- Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
- Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC