Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Stomach Mender Ingredients & Drug Interactions

by BioAnue

Stomach Mender label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stomach Mender against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Stomach Mender is a dietary supplement by BioAnue with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chaga Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Stomach Mender by BioAnue

Ask about any prescription or over-the-counter medication and we check it for interactions with Stomach Mender by BioAnue — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Stomach Mender by BioAnue

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (260 mg) without saying how much of each component you get.

Stomach Mender contains 3 active ingredients: pepsin (a digestive enzyme), bile extract, and chaga extract, blended together in a proprietary formula. Pepsin is a protease — an enzyme that breaks down protein in the stomach.

Bile extract supports fat digestion and nutrient absorption. Chaga is a mushroom extract used traditionally in teas and foods.

The capsule itself is made of gelatin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The product facts we hold don't include effectiveness ratings for pepsin or bile extract. For chaga extract, the evidence isn't established — we have insufficient reliable data to rate it for cardiovascular disease, diabetes, or COVID-19.

That doesn't mean it doesn't work; it means the science isn't settled yet.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Chaga

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pepsin is generally well tolerated for most adults, though it may cause digestive upset or allergic reactions in some people. Occupational exposure to airborne pepsin has rarely caused allergic rhinitis or asthma in workers.

Chaga is generally used in foods and teas, but human safety data are limited. There have been two reported cases of kidney failure and one case of acute kidney disease related to excessive chaga consumption due to its high oxalate content.

Safety hasn't been established in pregnancy or breastfeeding for either pepsin or chaga, so both should be avoided during pregnancy and breastfeeding unless your doctor advises otherwise.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Chaga

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Chaga.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use blood thinners or antiplatelet drugs like warfarin or clopidogrel, immunosuppressants, or antidiabetes medications — chaga may affect how they work. These are moderate-severity interactions that haven't been seen in humans yet, but they're worth confirming beforehand.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Stomach Mender may be worth considering if you're looking for digestive enzyme support, but the evidence for chaga's effectiveness isn't well established yet. If you take blood thinners, immunosuppressants, or diabetes medications, talk with your doctor or pharmacist before starting it.

Same goes if you're pregnant, breastfeeding, or have a history of kidney problems — get personalized advice from your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stomach Mender, straight from the product label.

Brand BioAnue
Net contents 90 Capsule(s); 260 mg
Market status On market
Date entered into DSLD Nov 25, 2013
DSLD ID 27485
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stomach Mender by BioAnue, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Proprietary Blend260 mg--
Pepsin0 Not Present--
Bile Extract0 Not Present--
Chaga Extract0 Not Present--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Your Edge - Your New Beginning

Date Code:

Suggested/Recommended/Usage/Directions

Usage: As a dietary supplement consume 1 capsule per meal, increasing by one capsule per day until stool is a dark brown color, or as directed by a health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stomach Mender by BioAnue label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stomach Mender label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stomach Mender by BioAnue

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

260 mg per serving

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stomach Mender by BioAnue Drug Interactions

Want to check YOUR meds against Stomach Mender?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Chaga Extract 327

Individual Drug Interactions

The ingredients in Stomach Mender interact with 327 drugs. Click any drug to see the details.

1 of the 3 ingredients in Stomach Mender interact with drugs. Each result below shows which ingredient is responsible. Chaga Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Stomach Mender with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chaga Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stomach Mender, from the product label.

BioAnue

See all BioAnue products
Name
BioAnue Laboratories Inc.
Street Address
P.O. Box 1056, 123 Wood Tech Dr.
City
Rochelle
State
GA
ZipCode
31079
Phone Number
(229) 365-7222
Pharmacist Counseling Corner

Stomach Mender by BioAnue: Common Questions

Does Stomach Mender by BioAnue interact with any medications?
Yes. Based on its ingredients, Stomach Mender has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stomach Mender contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Stomach Mender affect my blood thinner?
Chaga extract in this product may theoretically increase bleeding risk if you're on blood thinners or antiplatelet drugs — that's a moderate concern. This hasn't been reported in actual people, but it's important enough to discuss with your doctor or pharmacist before you start.
Can I take this while pregnant or breastfeeding?
No — safety data for both pepsin and chaga are too limited during pregnancy and breastfeeding. The facts advise against using either ingredient unless your doctor prescribes it. Talk with your own healthcare provider about whether it's right for you.
Does Stomach Mender actually work for digestion?
We don't have effectiveness ratings for pepsin or bile extract in our data. For chaga, the evidence isn't established — we can't say it works yet. That said, pepsin is a well-known digestive enzyme, but we can only tell you what the science we hold shows.
Are there any side effects I should know about?
Pepsin may cause digestive upset or allergic reactions in some people. Chaga is generally used in foods, but if you consume a lot of it, the high oxalate content has rarely caused kidney problems — so if you have kidney issues, mention this product to your doctor.
Is this safe if I take diabetes medication?
Chaga may theoretically increase the risk of low blood sugar if you're on antidiabetes drugs — a moderate concern that hasn't been seen in people yet. Check with your doctor or pharmacist before starting, especially if your blood sugar is already hard to manage.
What's bile extract for?
Bile extract supports fat digestion and nutrient absorption. We don't hold safety or effectiveness data for it, so we can't tell you much more — but your pharmacist can discuss it with you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stomach Mender label
Go deeper

The Full Monographs Behind Stomach Mender’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph →
Sources

Sources & How We Checked

Stomach Mender's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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