Interactions on record — worth a quick check against your medications. Based on 4 of 7 ingredients. Check your meds →
Dietary supplement

Super Healthy Prostate Ingredients & Drug Interactions

by Dr. David Williams

Super Healthy Prostate label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Healthy Prostate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Healthy Prostate is a dietary supplement by Dr. David Williams with 7 active ingredients. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 922 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cranberry powder, Selenium, Saw Palmetto extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Super Healthy Prostate by Dr. David Williams

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Healthy Prostate by Dr. David Williams — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Super Healthy Prostate by Dr. David Williams

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 7 active ingredients. Selenium is a trace mineral involved in thyroid function and antioxidant defense.

Saw palmetto extract is derived from the fruit of the saw palmetto plant and is commonly used for prostate health. Flower Pollen extract, Beta Sitosterol (a plant sterol), Meriva Curcumin Phytosome (a form of turmeric's active compound), Picea abies lignan extract (from spruce wood), and Cranberry powder round out the formula.

The inactive ingredients—including olive oil, gelatin, glycerin, and others—serve as fillers, binders, and capsule materials.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate health and function support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Urinary flow, Prostate size.
  • The strongest evidence on file: Beta-sitosterol is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Beta-sitosterol is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

The evidence for this product's ingredients is mixed. Selenium is likely effective for selenium deficiency and possibly effective for Kashin-Beck disease, pre-eclampsia, and autoimmune thyroiditis, but it appears ineffective for dyslipidemia (abnormal cholesterol).

Saw palmetto is possibly effective for symptoms after prostate surgery (TURP) but appears ineffective for benign prostatic hyperplasia (BPH), the condition many people take it for; evidence for other uses is insufficient. Beta-sitosterol is likely effective for benign prostatic hyperplasia and possibly effective for high cholesterol and heart disease.

Cranberry powder is possibly effective for urinary tract infections but has insufficient evidence for BPH, cognitive decline, cancer prevention, or other conditions. We hold no effectiveness data for Flower Pollen extract, Meriva Curcumin Phytosome, or Picea abies lignan extract.

The evidence, ingredient by ingredient Selenium Saw Palmetto Beta-sitosterol Cranberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Selenium is generally well tolerated in small recommended amounts, but excess selenium is toxic. Most common side effects from selenium are gastric discomfort, headache, and rash; excess amounts can cause hair loss, skin inflammation, fatigue, nail changes, nausea, vomiting, and weight loss.

Rare serious effects from excessive ingestion include multi-organ failure and death. Long-term exposure may increase the risk of ALS.

Selenium supplementation has been linked to increased risk of squamous cell skin cancer and total nonmelanoma skin cancer in one large trial. Saw palmetto is generally well tolerated with mild, infrequent, reversible side effects including abdominal pain, constipation, decreased libido, diarrhea, dizziness, fatigue, headache, nausea, and rhinitis.

A fixed drug eruption (blisters and erosions) was reported in one case, and worsening acne in combination with beta-sitosterol. Occasional reports exist of heart problems including high blood pressure, irregular heartbeat, and heart attack, though these are rare.

Saw palmetto is likely unsafe in pregnancy and lactation. Beta-sitosterol is generally well tolerated but can cause constipation, diarrhea, gas, indigestion, and nausea; it may worsen acne when taken alone or with saw palmetto.

There is insufficient safety data for beta-sitosterol in pregnancy and breastfeeding. Cranberry is likely safe in pregnancy and lactation.

It is generally well tolerated but can cause diarrhea and gastrointestinal discomfort; very large doses may cause nausea and vomiting. Skin rash has been reported rarely.

Side effects, ingredient by ingredient Selenium Saw Palmetto Beta-sitosterol Cranberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Cranberry, Saw Palmetto, Selenium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 923 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any blood thinners or antiplatelet drugs you take—selenium and saw palmetto may increase bleeding risk. If you take estrogens or contraceptive drugs, saw palmetto may reduce their effectiveness.

Patients on immune-suppressing medications should verify their use with a pharmacist, as selenium may interfere. If you take cholesterol-lowering statins (like atorvastatin), the blood pressure drug nifedipine, or warfarin, cranberry may increase their levels and side effects.

Selenium may also prolong the effects of barbiturates. Use the medication checker below with your complete medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines ingredients with some evidence for prostate and urinary health, but the evidence is stronger for some than others—and saw palmetto may not work as well as many people hope for BPH. If you take blood thinners, antiplatelet drugs, estrogens, contraceptives, statins, blood pressure medications, or immune suppressors, you'll need to check your exact medications before starting, because there are documented interactions.

Talk with your pharmacist or doctor about whether this product makes sense for you and your current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Healthy Prostate, straight from the product label.

Brand Dr. David Williams
Barcode (UPC) 678829214661
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230469
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Healthy Prostate by Dr. David Williams, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
60
UPC/BARCODE
678829214661
IngredientAmount% DV
Calories15 Calorie(s)--
Selenium100 mcg182%
Total Fat1.5 Gram(s)2%
Saw Palmetto extract160 mg--
Flower Pollen extract200 mg--
Beta Sitosterol30 mg--
Meriva Curcumin Phytosome125 mg--
Picea abies lignan extract15 mg--
Cranberry powder250 mg--

Other ingredients: Olive Oil, Gelatin, Glycerin, Microcrystalline Cellulose, yellow Beeswax, Maltodextrin, Sunflower Lecithin, purified Water, Carob extract, Dicalcium Phosphate, Silica, Calcium Stearate, Monocalcium Phosphate, Gum Arabic

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Almost out? Call 1-800-888-1415 or visit drwilliams.com Choose refill & save, get free shipping forever

Searching the world for better health

Formulation

Unconditionally guaranteed for purity and labeled potency.

Advanced support for prostate and urinary health

GF Gluten free

Storage

Store bottle with cap tightly closed in a cool, dry place.

Precautions

Precautions: Not intended for use by women.

Consult a health care practitioner before use if you have a serious medical condition or use any medications.

Keep out of reach of children.

Brand IP Statement(s)

Flowens is a tradeamrk of Naturex, Inc. Graminex G63 is trademark of Graminex LLC. Meriva is a registered trademark of Indena S.p.A. HMRlignan is a trademark of Linnea.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Standardization Levels: Saw palmetto extract: 85-95% free fatty acids

With flowens cranberry powder and graminex G63 flower pollen extract

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Doctor’s Suggested Use: Take 4 softgels daily- 2 softgels with a morning meal and 2 softgels with an evening meal.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Healthy Prostate by Dr. David Williams label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Healthy Prostate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Healthy Prostate by Dr. David Williams

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Selenium

Interacts with
321 drugs
100 mcg per serving Form: Selenomethionine

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...

Selenium monograph & interactions

Saw Palmetto extract

Interacts with
174 drugs
160 mg per serving

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto extract monograph & interactions

Flower Pollen extract

200 mg per serving

Beta Sitosterol

No known
interactions
30 mg per serving Form: Vegetable Oil

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta Sitosterol monograph & interactions

Meriva Curcumin Phytosome

125 mg per serving Form: Sunflower Lecithin, Turmeric extract

Picea abies lignan extract

15 mg per serving

Cranberry powder

Interacts with
712 drugs
250 mg per serving

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...

Cranberry powder monograph & interactions

Other (inactive) ingredients: Olive Oil, Gelatin, Glycerin, Microcrystalline Cellulose, Yellow Beeswax, Maltodextrin, Sunflower Lecithin, Purified Water, Carob extract, Dicalcium Phosphate, Silica, Calcium Stearate, Monocalcium Phosphate, Gum Arabic. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Healthy Prostate by Dr. David Williams Drug Interactions

Want to check YOUR meds against Super Healthy Prostate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
922Drugs
871 Moderate 51 Minor

Ingredients driving the most interactions

Cranberry powder 712
Selenium 321
Saw Palmetto extract 174

Individual Drug Interactions

The ingredients in Super Healthy Prostate interact with 922 drugs. Click any drug to see the details.

3 of the 7 ingredients in Super Healthy Prostate interact with drugs. Each result below shows which ingredient is responsible. Cranberry powder Selenium Saw Palmetto extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Healthy Prostate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cranberry powder6 drug types · 712 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
Cranberry powder full monograph & interactions

Selenium6 drug types · 321 drugs

Anticoagulant/Antiplatelet Drugs

Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.

Likelihood Possible Evidence D
Barbiturates

Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.

Likelihood Possible Evidence D
Contraceptive Drugs

Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.

Likelihood Possible Evidence B
Niacin

Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Selenium full monograph & interactions

Saw Palmetto extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Healthy Prostate, from the product label.

Dr. David Williams

See all Dr. David Williams products
Name
Healthy Directions
City
Bethesda
State
MD
ZipCode
20817
Web Address
healthydirections.com
Pharmacist Counseling Corner

Super Healthy Prostate by Dr. David Williams: Common Questions

Does Super Healthy Prostate by Dr. David Williams interact with any medications?
Yes. Based on its ingredients, Super Healthy Prostate has a known interaction with 922 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Healthy Prostate contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for benign prostatic hyperplasia (BPH)?
The evidence is mixed. Beta-sitosterol is likely effective for BPH, so that ingredient may help. But saw palmetto, which many people take specifically for BPH, appears to be ineffective based on the data we have. Cranberry has insufficient evidence for BPH. Talk with your doctor about whether it's worth trying.
Can I take this if I'm pregnant or breastfeeding?
Saw palmetto is likely unsafe during pregnancy and breastfeeding due to hormone effects and insufficient safety data—avoid it. Beta-sitosterol has insufficient safety data, so it's best to avoid supplemental use during pregnancy and breastfeeding. Cranberry is likely safe in both. Always check with your doctor or pharmacist before starting any supplement during pregnancy or lactation.
What are the most common side effects?
Selenium can cause gastric discomfort, headache, and rash. Saw palmetto may cause abdominal pain, diarrhea, dizziness, fatigue, headache, and nausea. Beta-sitosterol can cause constipation, diarrhea, gas, and indigestion. Cranberry may cause diarrhea and gastrointestinal discomfort. Most are mild and reversible.
Is there a risk of taking too much selenium in this product?
Selenium is generally well tolerated up to 400 mcg daily, but excess amounts are toxic. High doses can cause hair loss, skin inflammation, nail changes, nausea, vomiting, weight loss, and in rare cases multi-organ failure. Don't exceed recommended doses, and avoid combining with other selenium supplements.
What is beta-sitosterol and what does it do?
Beta-sitosterol is a plant sterol that is likely effective for benign prostatic hyperplasia and possibly effective for lowering cholesterol and supporting heart health. It is generally well tolerated, though it can cause mild gastrointestinal symptoms in some people.
Can cranberry in this product interact with my medications?
Yes. Cranberry may increase the levels of statins (like atorvastatin), the blood pressure drug nifedipine, warfarin (a blood thinner), and some other medications metabolized by your liver. It can also modestly affect diclofenac. Check your exact medications with the tool on this page before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Healthy Prostate label
Go deeper

The Full Monographs Behind Super Healthy Prostate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Selenium

Interacts with 321 drugs

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who eat a varied diet get enough, and supple...

Read the full Selenium monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Beta-sitosterol

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Evidence is moderate for these uses and weaker...

Read the full Beta-sitosterol monograph → Herb & supplement monograph

Cranberry

Interacts with 712 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph →
Sources

Sources & How We Checked

Super Healthy Prostate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 98 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Selenium 36 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  2. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  3. Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
  4. Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
  5. Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
  6. Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
  7. Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
  8. Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
  9. Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
  10. Capel ID, Jenner M, Williams DC, et al. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem 1981;14:729-32. PubMed
  11. Contempre B, Dumont JE, Ngo B, et al. Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. J Clin Endocrinol PubMed
  12. Hofbauer LC, Spitzweg C, Magerstadt RA, Heufelder AE. Selenium-induced thyroid dysfunction. Postgrad Med J 1997;73:103-4. PubMed
  13. Debski B, Milner JA. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem 2004;15:548-53. PubMed
  14. Ishikawa M, Sasaki M, Koiwai K, et al. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J Pharmacobiodyn 1992;15:377-85. PubMed
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Saw Palmetto 22 references
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Beta-sitosterol 7 references
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Cranberry 33 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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