Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Sweet Clover (Melilot) Herb Ingredients & Drug Interactions

by TerraVita

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sweet Clover (Melilot) Herb is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for varicose veins and poor circulation, leg swelling (edema), hemorrhoids.Based on those ingredients, 480 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sweet Clover Herb Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sweet Clover (Melilot) Herb by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Sweet Clover Herb Glycerite Liquid Extract. Sweet clover is an herb traditionally used for symptoms related to poor circulation in the legs and other conditions, though the evidence supporting these uses is not yet well established.

The liquid is made using glycerin, which is also listed as an inactive ingredient to help preserve and deliver the herb.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Sweet Clover's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: circulatory health and swelling support.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Hemorrhoids, Bruises, varicose veins, edema, poor circulation.
  • The closest evidence on file: Sweet Clover is rated "Insufficient Reliable Evidence To Rate" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Sweet Clover is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Bruises.

The evidence for sweet clover is insufficient to establish whether it works for any of its traditional uses — chronic venous insufficiency (leg swelling from poor circulation), diabetic nerve pain, hemorrhoids, or postoperative pain. The data we hold doesn't show that it's proven effective for these conditions, but it also doesn't mean it doesn't work; it means more study is needed.

The evidence, ingredient by ingredient Sweet Clover

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sweet clover is generally used in small amounts, but its coumarin content — the same compound in blood thinners — means you need to be cautious, especially with bleeding or liver concerns. The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know it's safe.

Large amounts can cause temporary liver injury in susceptible people, and rare cases of headache have been reported. One case of bleeding problems was reported after taking a multi-herb tea containing sweet clover and other coumarin-rich herbs for two months, though it's unclear whether sweet clover alone was responsible.

Side effects, ingredient by ingredient Sweet Clover

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Clover.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 481 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take blood thinners (anticoagulants or antiplatelets like warfarin or clopidogrel) or any medication that's hard on the liver. Both interactions are moderate severity.

The medication search tool on this page can help you confirm whether any of your specific drugs are affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in sweet clover for circulation or nerve pain, know that the evidence doesn't yet support these uses. More importantly, don't start this if you take blood thinners or medications that stress your liver without checking with your pharmacist first.

Pregnant or breastfeeding? This one's best avoided.

Talk to us before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sweet Clover (Melilot) Herb, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435230975
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279382
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sweet Clover (Melilot) Herb by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435230975
IngredientAmount% DV
Sweet Clover Herb Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free

No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

See for yourself

Sweet Clover (Melilot) Herb by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sweet Clover (Melilot) Herb by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

0.13 mL per serving

Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limited. It con...

Sweet Clover Herb Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sweet Clover (Melilot) Herb by TerraVita Drug Interactions

Want to check YOUR meds against Sweet Clover (Melilot) Herb?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
480Drugs
480 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sweet Clover (Melilot) Herb with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sweet Clover Herb Glycerite Liquid Extract2 drug types · 480 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Fresh sweet clover contains coumarinic acids, which are converted to free coumarins during drying. Dicoumarol, which has anticoagulant activity, also has been found in some sweet clover preparations and can be formed if fresh sweet clover is allowed to spoil.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of sweet clover with hepatoxic drugs might increase the risk of hepatotoxicity.
Orally, large amounts of sweet clover can cause transient liver injury in susceptible individuals, possibly due to coumarin content. In one case report, a patient with multiple sclerosis developed jaundiced palms and a slight elevation in serum alanine aminotransferase (ALT) after taking sweet clover containing coumarin 10 mg daily for 3 years. Two weeks after starting therapy with subcutaneous interferon (IFN)-beta 1b, aspartate transaminase (AST) and ALT levels increased to 7 and 17 times the upper limit of normal, respectively. Levels normalized after discontinuation of both products. Subsequent use of IFN-beta 1a alone, without sweet clover, resulted in only a very slight increase in AST.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sweet Clover (Melilot) Herb, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Sweet Clover (Melilot) Herb by TerraVita: Common Questions

Does Sweet Clover (Melilot) Herb by TerraVita interact with any medications?
Yes. Based on its ingredients, Sweet Clover (Melilot) Herb has a known interaction with 480 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sweet Clover (Melilot) Herb contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No — the safety data advises against it during pregnancy because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about whether it's right for you before you use it.
Is this safe while breastfeeding?
The safety data advises against it while breastfeeding because it's not known whether it's safe. Speak with your doctor or pharmacist for personalized advice.
What is sweet clover actually used for?
Traditionally, sweet clover has been used to help with poor circulation in the legs, nerve pain from diabetes, hemorrhoids, and pain after surgery. However, we don't have reliable evidence showing it works for any of these yet.
Can large amounts of this cause side effects?
Yes. Large amounts can cause temporary liver injury in some people, and in rare cases, headache has been reported. There's also one reported case of bleeding problems after taking a multi-herb tea containing sweet clover and similar herbs for two months.
Why does sweet clover interact with blood thinners?
Sweet clover contains coumarin compounds — the same active ingredient in blood-thinning medications like warfarin. Using them together could increase your bleeding risk, so you need to check with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sweet Clover (Melilot) Herb is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sweet Clover (Melilot) Herb label
Go deeper

The Full Monographs Behind Sweet Clover (Melilot) Herb’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sweet Clover (Melilot) Herb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Clover 6 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  3. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Hogan RP III. Hemorrhagic diathesis caused by drinking an herbal tea. JAMA 1983;249:2679-80. DOI
  6. Tamura S, Warabi Y, Matsubara S. Severe liver dysfunction possibly caused by the combination of interferon beta-1b therapy and melilot (sweet clover) supplement. J Clin Pharm Ther 2012;37(6):724-5. PubMed

See these in context on the Sweet Clover monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring