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Dietary supplement

LymphaQOL Ingredients & Drug Interactions

by OncoQOL

LymphaQOL label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LymphaQOL against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LymphaQOL is a dietary supplement by OncoQOL with 1 active ingredient. Its ingredients are commonly taken for varicose veins and poor circulation, leg swelling (edema), hemorrhoids.Based on those ingredients, 480 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Yellow Sweetclover extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against LymphaQOL by OncoQOL

Ask about any prescription or over-the-counter medication and we check it for interactions with LymphaQOL by OncoQOL — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of LymphaQOL by OncoQOL

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

LymphaQOL contains one active ingredient: yellow sweetclover extract. The product also includes inactive ingredients — hypromellose capsule, microcrystalline cellulose, silicon dioxide, and leucine — which are fillers and binders that help form and fill the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Sweet Clover's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promotes healthy lymphatic flow.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Hemorrhoids, Postoperative swelling, lymphedema, lymphatic dysfunction, edema.
  • The closest evidence on file: Sweet Clover is rated "Insufficient Reliable Evidence To Rate" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Sweet Clover is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Postoperative swelling.

The evidence for yellow sweetclover in this product isn't established. We have insufficient reliable evidence to rate its use for chronic venous insufficiency (swelling and heaviness in the legs from poor circulation), diabetic neuropathy (nerve pain from diabetes), hemorrhoids, or postoperative pain.

That doesn't mean it doesn't work — it means the studies we have don't yet prove it does.

The evidence, ingredient by ingredient Sweet Clover

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sweetclover is generally used in small amounts, but its coumarin content (a compound that affects bleeding and liver function) means you should be cautious. In rare cases, large amounts can cause headache or even liver injury — one case report described a woman who developed jaundiced skin after taking a sweetclover supplement with 10 mg of coumarin daily.

There's also one report of bleeding problems after someone took a multi-herb tea containing sweetclover and other coumarin-rich herbs for two months, though it's unclear whether sweetclover alone was responsible. The safety data advises against using this product during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations.

Talk with your doctor or pharmacist about whether this product is right for you, especially if you're pregnant, nursing, or considering either.

Side effects, ingredient by ingredient Sweet Clover

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Clover.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 481 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking LymphaQOL, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, dabigatran, or aspirin) — the sweetclover extract might increase bleeding risk. Also flag any medications that stress the liver (hepatotoxic drugs).

No interactions are documented in our data for other ingredient categories we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

LymphaQOL is a single-ingredient product best suited for people with chronic venous insufficiency or related conditions who are not on blood thinners or liver-stressing medications. If you take any anticoagulants, antiplatelet drugs, or medications that affect the liver, you'll need to clear this with your doctor or pharmacist first.

Pregnant or breastfeeding? Skip it and talk with your healthcare provider about safer options.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LymphaQOL, straight from the product label.

Brand OncoQOL
Barcode (UPC) 693749001195
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2012
DSLD ID 15557
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LymphaQOL by OncoQOL, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
693749001195
IngredientAmount% DV
Yellow Sweetclover extract400 mg--

Other ingredients: Hypromellose (derived from Cellulose) Capsule, Microcrystalline Cellulose, Silicon Dioxide, Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

This product uses Indena S.p.A.’s yellow sweetclover, Lymphaselect(R), which is a trademark of Indena S.p.A., standardized to 17% Coumarin.

Enhancing Quality of Life Through Targeted Nutraceuticals(TM)

General Statements

Promotes healthy lymphatic flow

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily or as recommended by your health-care practitioner.

Precautions

Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Storage

Store tightly sealed in a cool, dry place.

Seals/Symbols

(pulled apart capsule)(R)

Formula

HYPOALLERGENIC

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

QOL107 LQOL10702

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LymphaQOL by OncoQOL label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LymphaQOL label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LymphaQOL by OncoQOL

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Yellow Sweetclover extract

Interacts with
480 drugs
400 mg per serving

Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limited. It con...

Yellow Sweetclover extract monograph & interactions

Other (inactive) ingredients: Hypromellose (derived from Cellulose) Capsule, Microcrystalline Cellulose, Silicon Dioxide, Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

LymphaQOL by OncoQOL Drug Interactions

Want to check YOUR meds against LymphaQOL?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
480Drugs
480 Moderate

Ingredients driving the most interactions

Yellow Sweetclover extract 480

Individual Drug Interactions

The ingredients in LymphaQOL interact with 480 drugs. Click any drug to see the details.

1 of the 1 ingredient in LymphaQOL interact with drugs. Each result below shows which ingredient is responsible. Yellow Sweetclover extract

Each ingredient & the kinds of drugs it affects

For each ingredient in LymphaQOL with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Yellow Sweetclover extract2 drug types · 480 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Fresh sweet clover contains coumarinic acids, which are converted to free coumarins during drying. Dicoumarol, which has anticoagulant activity, also has been found in some sweet clover preparations and can be formed if fresh sweet clover is allowed to spoil.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of sweet clover with hepatoxic drugs might increase the risk of hepatotoxicity.
Orally, large amounts of sweet clover can cause transient liver injury in susceptible individuals, possibly due to coumarin content. In one case report, a patient with multiple sclerosis developed jaundiced palms and a slight elevation in serum alanine aminotransferase (ALT) after taking sweet clover containing coumarin 10 mg daily for 3 years. Two weeks after starting therapy with subcutaneous interferon (IFN)-beta 1b, aspartate transaminase (AST) and ALT levels increased to 7 and 17 times the upper limit of normal, respectively. Levels normalized after discontinuation of both products. Subsequent use of IFN-beta 1a alone, without sweet clover, resulted in only a very slight increase in AST.

Likelihood Possible Evidence D
Yellow Sweetclover extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LymphaQOL, from the product label.

OncoQOL

See all OncoQOL products
Name
Thorne Research, Inc.
Street Address
P.O. Box 25
City
Dover
State
Idaho
ZipCode
83825
Phone Number
1-855-662-6765
Pharmacist Counseling Corner

LymphaQOL by OncoQOL: Common Questions

Does LymphaQOL by OncoQOL interact with any medications?
Yes. Based on its ingredients, LymphaQOL has a known interaction with 480 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LymphaQOL contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is yellow sweetclover extract supposed to do?
Yellow sweetclover extract is used in traditional herbalism for chronic venous insufficiency — that's the swelling and heaviness you feel in your legs when circulation isn't great. We don't yet have solid evidence it works for that condition or for nerve pain, hemorrhoids, or postoperative pain, though that doesn't mean it won't help you.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking with your doctor or pharmacist first. Sweetclover contains compounds that have anticoagulant activity — meaning they can thin your blood — so combining it with prescription blood thinners could increase your bleeding risk. Your healthcare provider needs to weigh the benefits against that risk for your situation.
Is it safe to take large amounts of this?
No. While this product is meant to be used in small amounts, large doses of sweetclover can cause liver injury in some people and have been tied to headache and even bleeding problems when combined with other coumarin-containing herbs. Stick to the label dose and tell your doctor or pharmacist if you're taking it.
Can I take this while pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know whether it's safe during pregnancy or while breastfeeding, so it's best avoided in both. Talk with your doctor or pharmacist about what might work better for you during these times.
What are the side effects I should watch for?
Headache has been reported rarely. The main concern is liver injury — one documented case involved jaundiced skin and elevated liver enzymes. There's also a report of bleeding problems after someone took a multi-herb tea containing sweetclover for two months, though it's not clear whether sweetclover alone caused it.
Does this product contain any fillers or binders?
Yes. Besides the active sweetclover extract, it contains microcrystalline cellulose, hypromellose (a plant-derived capsule material), silicon dioxide, and leucine — all inactive ingredients that help form the capsule and keep the product stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LymphaQOL label
Go deeper

The Full Monographs Behind LymphaQOL’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sweet Clover

Interacts with 480 drugs

Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limited. It contains coumarin, which can become dangero...

Read the full Sweet Clover monograph →
Sources

Sources & How We Checked

LymphaQOL's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Clover 6 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  3. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Hogan RP III. Hemorrhagic diathesis caused by drinking an herbal tea. JAMA 1983;249:2679-80. DOI
  6. Tamura S, Warabi Y, Matsubara S. Severe liver dysfunction possibly caused by the combination of interferon beta-1b therapy and melilot (sweet clover) supplement. J Clin Pharm Ther 2012;37(6):724-5. PubMed

See these in context on the Sweet Clover monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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