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Dietary supplement

Sweet Clover Herb (Melilot) 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Sweet Clover Herb (Melilot) 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sweet Clover Herb (Melilot) 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sweet Clover Herb (Melilot) 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for varicose veins and poor circulation, leg swelling (edema), hemorrhoids.Based on those ingredients, 482 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sweet Clover. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 450 mg of sweet clover (also called melilot), a traditional herb. Sweet clover gets its activity from compounds called coumarins, which are naturally present in the plant and can increase to higher levels as the herb dries.

The capsule itself is made from gelatin and water — those are the only inactive ingredients here.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sweet Clover product and its label doesn't state a use — see Sweet Clover's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that sweet clover works for any of the conditions it's traditionally used for. These include chronic venous insufficiency (poor circulation in leg veins), diabetic neuropathy (nerve pain from diabetes), hemorrhoids, and postoperative pain — all rated as having insufficient reliable evidence to rate in our data.

The evidence, ingredient by ingredient Sweet Clover

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sweet clover is generally used in small amounts, but its coumarin content means you need to be cautious, especially regarding bleeding and liver health. Large amounts can cause temporary liver injury in susceptible people — one case report documented a woman with multiple sclerosis who developed yellowing of her palms and a slight rise in liver enzymes after taking 10 mg of coumarin daily from a sweet clover supplement.

During pregnancy, there isn't enough safety information available, so it's best avoided. The same goes for breastfeeding — safety data just isn't on file.

Although rare, headache has been reported, and very large amounts can cause stupor. One case of bleeding problems was reported after long-term use of a multi-herb tea containing sweet clover and other coumarin-containing herbs, though it's unclear whether sweet clover alone was responsible.

Side effects, ingredient by ingredient Sweet Clover

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Clover.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 483 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check your medications against blood thinners and antiplatelet drugs (warfarin, aspirin, clopidogrel, and similar medications) — sweet clover may increase bleeding risk. Also flag any drugs known to stress your liver (hepatotoxic medications), as sweet clover can add to that burden.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Sweet clover may be worth considering if you're exploring options for poor leg circulation or related conditions, but the evidence supporting it isn't solid yet. If you take blood thinners, antiplatelet drugs, or medications that stress your liver, this supplement needs a careful review with your doctor or pharmacist before you start.

Avoid it during pregnancy and breastfeeding. Talk with your own healthcare provider about whether it's right for you and your specific situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sweet Clover Herb (Melilot) 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435126711
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 286628
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435126711
IngredientAmount% DV
Sweet Clover450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2005 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sweet Clover Herb (Melilot) 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Sweet Clover

Interacts with
482 drugs
450 mg per serving

Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limited. It con...

Sweet Clover monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Sweet Clover Herb (Melilot) 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
482Drugs
482 Moderate

Ingredients driving the most interactions

Sweet Clover 482

Individual Drug Interactions

The ingredients in Sweet Clover Herb (Melilot) 450 mg interact with 482 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sweet Clover Herb (Melilot) 450 mg interact with drugs. Each result below shows which ingredient is responsible. Sweet Clover

Each ingredient & the kinds of drugs it affects

For each ingredient in Sweet Clover Herb (Melilot) 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sweet Clover2 drug types · 482 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Fresh sweet clover contains coumarinic acids, which are converted to free coumarins during drying. Dicoumarol, which has anticoagulant activity, also has been found in some sweet clover preparations and can be formed if fresh sweet clover is allowed to spoil.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of sweet clover with hepatoxic drugs might increase the risk of hepatotoxicity.
Orally, large amounts of sweet clover can cause transient liver injury in susceptible individuals, possibly due to coumarin content. In one case report, a patient with multiple sclerosis developed jaundiced palms and a slight elevation in serum alanine aminotransferase (ALT) after taking sweet clover containing coumarin 10 mg daily for 3 years. Two weeks after starting therapy with subcutaneous interferon (IFN)-beta 1b, aspartate transaminase (AST) and ALT levels increased to 7 and 17 times the upper limit of normal, respectively. Levels normalized after discontinuation of both products. Subsequent use of IFN-beta 1a alone, without sweet clover, resulted in only a very slight increase in AST.

Likelihood Possible Evidence D
Sweet Clover full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sweet Clover Herb (Melilot) 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection: Common Questions

Does Sweet Clover Herb (Melilot) 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Sweet Clover Herb (Melilot) 450 mg has a known interaction with 482 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sweet Clover Herb (Melilot) 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take sweet clover if I'm on a blood thinner like warfarin?
No — sweet clover contains coumarins that can increase bleeding risk when combined with blood thinners. Talk with your doctor or pharmacist before adding this supplement; they may need to adjust how you're managed or advise against it altogether.
Is sweet clover safe during pregnancy?
No. There isn't enough safety information available, so it's best avoided during pregnancy. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before considering this supplement.
Can sweet clover damage my liver?
Large amounts can cause temporary liver injury in susceptible people. One documented case involved a woman taking 10 mg of coumarin daily (the active compound in sweet clover) who developed yellowing of her palms and a slight rise in liver enzymes. If you have liver disease or take other drugs that stress your liver, discuss this with your pharmacist or doctor first.
Does sweet clover actually work for circulation problems?
The evidence we hold doesn't establish that it works for chronic venous insufficiency or other conditions it's traditionally used for. The data rate these as having insufficient reliable evidence.
What's in this product besides sweet clover?
Just gelatin and water — the capsule ingredients. The active ingredient is the 450 mg of sweet clover itself, so there are no fillers or other actives.
Can I take this while breastfeeding?
Safety while breastfeeding isn't known, so it's best avoided. If you're breastfeeding, talk with your doctor or pharmacist about whether this is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sweet Clover Herb (Melilot) 450 mg label
Go deeper

The Full Monographs Behind Sweet Clover Herb (Melilot) 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sweet Clover

Interacts with 482 drugs

Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limited. It contains coumarin, which can become dangero...

Read the full Sweet Clover monograph →
Sources

Sources & How We Checked

Sweet Clover Herb (Melilot) 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Clover 6 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  3. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Hogan RP III. Hemorrhagic diathesis caused by drinking an herbal tea. JAMA 1983;249:2679-80. DOI
  6. Tamura S, Warabi Y, Matsubara S. Severe liver dysfunction possibly caused by the combination of interferon beta-1b therapy and melilot (sweet clover) supplement. J Clin Pharm Ther 2012;37(6):724-5. PubMed

See these in context on the Sweet Clover monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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