Sweet Clover - Brilinta (Ticagrelor) Interaction
Herbal: Sweet Clover
Also Known As: Melilotus officinalis, Angipars, Casse Lunettes, Common Melilot, Couronne Royale, Field Melilot, Hart's Tree, Hay Flower, Herbe aux Puces, King's Clover, Luzerne Bâtarde, Melilot, Mélilot, Mélilot des Champs, Mélilot Commun, Mélilot Jaune, Mélilot Officinal
Drug: Ticagrelor
Brand names:
Brilinta
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 18, 2025
Interaction Details
Ticagrelor is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Fresh sweet clover contains coumarinic acids, which are converted to free coumarins during drying. Dicoumarol, which has anticoagulant activity, also has been found in some sweet clover preparations and can be formed if fresh sweet clover is allowed to spoil.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Sweet Clover Overview
Sweet clover is a tall, herbaceous plant with yellow flowers that belongs to the pea family (Fabaceae). It is native to Europe and Asia, but has been introduced to many other parts of the world, including North America. There are two main species of sweet clover: Melilotus albus, which is white sweet clover, and Melilotus officinalis, which is yellow sweet clover. Sweet clover is purported to have a number of medicinal properties and has been used traditionally to treat a variety of ailments, such as respiratory problems and skin conditions. It has also been used as a phlebotonic (drug that modifies the tone of vein walls) and an antithrombotic.
Ticagrelor Overview
-
Ticagrelor is used to prevent a serious or life-threatening heart attack or stroke, or death in people who have had a heart attack or who have acute coronary syndrome (ACS; blockage of blood flow to the heart). It is also used to prevent blood clots from forming in people who have received coronary stents (metal tubes surgically placed in clogged blood vessels to improve blood flow) to treat ACS. Ticagrelor is used to decrease the risk of a first-time heart attack or stroke in people at risk with coronary artery disease (CAD; reduced blood flow to the heart). It is also used to decrease the risk of another more serious stroke in people who are having a mild to moderate stroke or a transient ischemic attack (TIA; ministroke). Ticagrelor is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.
Sweet Clover - More Interactions
Sweet Clover interacts with 453 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist