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Dietary supplement

Teacrine Ingredients & Drug Interactions

by Pure Nootropics

Teacrine label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Teacrine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Teacrine is a dietary supplement by Pure Nootropics with 1 active ingredient. Its ingredients are commonly taken for energy and reduced fatigue, focus and mental alertness, mood support.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are TeaCrine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Teacrine by Pure Nootropics

Ask about any prescription or over-the-counter medication and we check it for interactions with Teacrine by Pure Nootropics — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Teacrine by Pure Nootropics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TeaCrine contains one active ingredient: theacrine (also called TeaCrine), a compound similar to caffeine that's naturally found in some plants. The product also includes two inactive ingredients — hypromellose and maltodextrin — which are used to form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Theacrine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: energy, focus, and mental alertness.
  • We looked for evidence on: Fatigue, Mental alertness, Cognitive function, Athletic performance, endurance, stamina.
  • The closest evidence on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Fatigue, Mental alertness.

The evidence isn't established in our data for any of theacrine's claimed uses: athletic performance, cognitive function, fatigue, mental alertness, and muscle strength all carry insufficient reliable evidence ratings. That doesn't mean the ingredient doesn't work — it means the research isn't solid enough yet for us to rate it.

The evidence, ingredient by ingredient Theacrine

How safe is it?

Limited data
Safety Information · database check
Limited information

Little studied safety information is available for these ingredients — that is not the same as being safe.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of theacrine appears generally well tolerated in studies, but long-term safety isn't well established, so if you're thinking of taking this for weeks or months, that's a conversation to have with your pharmacist. There's not enough safety data to recommend TeaCrine during pregnancy or while breastfeeding — the safety data advises against both.

Side effects, ingredient by ingredient Theacrine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Theacrine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any CNS depressants — sedatives, sleep aids, anti-anxiety medications, and similar drugs that slow down your nervous system. Theacrine might either increase or decrease how they work on you, which is unpredictable and worth discussing with your pharmacist before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is limited.

TeaCrine is a single-ingredient supplement that hasn't been proven to work for its marketed uses yet. If you're considering it, check your medications first — especially anything that makes you drowsy.

Pregnant people and those breastfeeding should skip it. Talk to your pharmacist about whether this fits your needs and your health profile.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Teacrine, straight from the product label.

Brand Pure Nootropics
Barcode (UPC) 854051008580
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 316608
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Teacrine by Pure Nootropics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
854051008580
IngredientAmount% DV
TeaCrine100 mg--

Other ingredients: Hypromellose, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Consult with a healthcare practitioner before taking this.

Do not take this if you are pregnant, nursing, or under the age of 18.

Do not take this if you are pregnant, nursing, or under the age of 18.

If you experience adverse reactions from taking this product, discontinue immediately and contact a healthcare practitioner.

Keep out of reach of children

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 capsule daily or as recommended by your healthcare practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

TeaCrine is a trademark and is protected by Patents Pending claiming priority to Serial No. 61/903,362; under exclusive global distribution by Compound Solutions, Inc

Formulation

Lab tested for purity

Formula

TeaCrine from compound solutions

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Teacrine by Pure Nootropics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Teacrine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Teacrine by Pure Nootropics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

TeaCrine

Interacts with
248 drugs
100 mg per serving Form: Theacrine

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studie...

TeaCrine monograph & interactions

Other (inactive) ingredients: Hypromellose, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Teacrine by Pure Nootropics Drug Interactions

Want to check YOUR meds against Teacrine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

TeaCrine 248

Individual Drug Interactions

The ingredients in Teacrine interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Teacrine interact with drugs. Each result below shows which ingredient is responsible. TeaCrine

Each ingredient & the kinds of drugs it affects

For each ingredient in Teacrine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

TeaCrine1 drug type · 248 drugs

Cns Depressants

Theoretically, theacrine might alter the effects of CNS depressants.
Animal research shows that low doses of theacrine have sedating effects, whereas high doses might have stimulant effects. Depending on the dose of theacrine used, it might increase or decrease the effects of CNS depressants. However, these effects have not yet been reported in humans.

Likelihood Possible Evidence D
TeaCrine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Teacrine, from the product label.

Pure Nootropics

See all Pure Nootropics products
Name
Pure Nootropics, LLC
Street Address
P.O. Box 6827
City
Albuquerque
State
NM
ZipCode
87197
Web Address
purenootropics.net
Pharmacist Counseling Corner

Teacrine by Pure Nootropics: Common Questions

Does Teacrine by Pure Nootropics interact with any medications?
Yes. Based on its ingredients, Teacrine has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Teacrine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take TeaCrine if I'm pregnant or breastfeeding?
No. The safety data advises against using it during pregnancy and while breastfeeding because there isn't enough information to know it's safe for you or your baby. Talk with your doctor or pharmacist about alternatives if you're in either situation.
Is theacrine the same as caffeine?
No — they're similar compounds, but theacrine is different. It's naturally found in some plants and works on your body in its own way. The evidence hasn't firmly established what it does for you yet.
How long can I safely take TeaCrine?
Short-term use appears generally well tolerated in studies, but we don't have solid data on long-term safety. If you're planning to take it for more than a few weeks, check with your pharmacist first.
Will TeaCrine help me stay alert or boost my workout?
The evidence we hold isn't strong enough to say. Mental alertness and athletic performance both have insufficient reliable evidence ratings, so we can't confirm it works for those uses yet.
What's in the capsule besides theacrine?
Two inactive ingredients: hypromellose and maltodextrin. These are used to form and stabilize the capsule — they're not the active part of the product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Teacrine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Teacrine label
Go deeper

The Full Monographs Behind Teacrine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theacrine

Interacts with 248 drugs

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studies suggest it may give a stimulant-like b...

Read the full Theacrine monograph →
Sources

Sources & How We Checked

Teacrine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theacrine 1 reference
  1. Xu JK, Kurihara H, Zhao L, Yao XS. Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. J Asian Nat Prod Res 2007;9(6-8):665-72.

See these in context on the Theacrine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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