Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Test 7 PCT Ingredients & Drug Interactions

by Image Sports

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Test 7 PCT is a dietary supplement by Image Sports with 4 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, skin moisturizing, menstrual cramps.Based on those ingredients, 1,063 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ginger, Clove, Safflower. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Test 7 PCT by Image Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “ULTRA CONCENTRATED TEST BOOSTING / PCT MATRIX(TM)” is a proprietary blend — the label gives one combined amount (450 mg) without saying how much of each component you get.

Test 7 PCT contains 4 active ingredients. Safflower oil is derived from safflower seeds and has been studied for blood circulation and heart health, though evidence is limited.

Clove comes from clove flower buds and has traditional uses for pain and digestion. Ginger root is widely used for nausea and inflammation.

Curculigo is also included but we hold limited information on its role. The product is completed with inactive ingredients that serve as the capsule shell (gelatin), filler (microcrystalline cellulose, magnesium stearate), color (Capsicum annuum, FD&C Blue No.

1, titanium dioxide).

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: muscle building and strength training support.
  • We looked for evidence on: Exercise-induced muscle soreness, Muscle recovery, Athletic performance, Lean muscle gain.
  • The closest evidence on file: Ginger is rated "Possibly Ineffective" for Exercise-induced muscle soreness (Natural Medicines).

The evidence for these ingredients is mixed and limited. Ginger is possibly effective for pregnancy-related nausea, period pain, and osteoarthritis—but possibly ineffective for exercise soreness and chemotherapy nausea.

Clove appears possibly effective for ventilator-associated pneumonia (a hospital-acquired lung infection), though real-world use is limited. For safflower, evidence is insufficient to rate it for heart disease, diabetes, cystic fibrosis, or related conditions—meaning we don't have enough reliable studies to say whether it works for these uses.

Effectiveness data on curculigo is not on file.

The evidence, ingredient by ingredient Safflower Clove Ginger

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Safflower oil from food is generally well tolerated, but concentrated extracts and high-dose supplements have less safety data. Serious but rare cases of liver failure have been reported with overuse, typically for weight loss—though the exact dose or duration isn't always clear.

Safflower flower may stimulate the uterus and should be avoided in medicinal amounts during pregnancy; there isn't enough data on medicinal safflower during breastfeeding. Ginger is generally well tolerated at typical food and supplement doses, though doses above 5 grams daily increase side effects like heartburn, burping, and diarrhea.

Clove is safe as a food spice but concentrated oils can be toxic; clove oil at just 5–10 mL doses has caused serious harm in children. Most adverse effects from clove are topical irritation, though rare liver failure and CNS depression have been reported with accidental overdose.

There isn't enough data on medicinal clove during breastfeeding.

Side effects, ingredient by ingredient Safflower Clove Ginger

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Safflower, Clove, Ginger.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,064 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take blood thinners or antiplatelet drugs (Moderate risk of increased bleeding), diabetes medications (Moderate risk of low blood sugar), warfarin or similar anticoagulants (Moderate risk), nifedipine for blood pressure (Moderate risk), or medications metabolized through CYP3A4, CYP2D6, CYP1A2, CYP2C9 pathways, or P-glycoprotein (Moderate risk of increased drug levels). Ginger, safflower, and clove all contribute to these interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Test 7 PCT is mainly a concern if you take blood thinners (including warfarin), diabetes medications, or certain cancer drugs. If you're on any prescription medication—or if you're pregnant or breastfeeding—check with your pharmacist or doctor before starting.

The safflower and clove ingredients are potent at high doses, and the interaction potential is real.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Test 7 PCT, straight from the product label.

Brand Image Sports
Barcode (UPC) 859123003883
Net contents 28 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2014
DSLD ID 31185
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Test 7 PCT by Image Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
28
UPC/BARCODE
859123003883
IngredientAmount% DV
Safflower0 Not Present--
Curculigo0 Not Present--
Clove0 Not Present--
ULTRA CONCENTRATED TEST BOOSTING / PCT MATRIX(TM)450 mg--
Ginger0 Not Present--

Other ingredients: Gelatin, Microcrystalline Cellulose, Capsicum annuum, Magnesium Stearate, FD&C Blue No. 1, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

LIMITED EDITION INCLUDES: 1 MONTH SUPPLY 7 DAY FAST TRACK PLAN FREE TRAINING T-SHIRT SEE BACK SIDE FOR DETAILS >>

For use in conjunction with: MASS / MUSCLE BUILDING PROGRAMS* – STRENGTH TRAINING*

HIGH SPEED 3-IN-1 REGIMEN

When combined with a proper exercise and nutrition regimen. Statements based on early-stage independent 3rd party in vivo and / or in vitro model scientific research data findings.

FREE T-SHIRT INSIDE! XL SIZE ONLY

THE ULTIMATE 1 MONTH PROTOCOL FOR MUSCLE BUILDING PROGRAMS*

Please read entire label before use.

Seals/Symbols

i IMAGESPORTS

TEST 7 PCT(TM)

General

Rev. 01-003-BIG002 06/13

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.

Brand IP Statement(s)

The B.I.G(TM) Kit is a High Speed, 3-IN-1, regimen designed to support the proper foundation for building muscle.* This is the ultimate supplement combination, and IMAGE SPORTS has it down - lock and key.* MUSCLE AGENT(TM), ALARM ULTRA(TM) and TEST 7 PCT(TM) are intended to work in synergy in this mind-blowing muscular initiative.*

MUSCLE AGENT(TM), ALARM ULTRA(TM) and TEST 7 PCT(TM) are intended to work in synergy in this mind-blowing muscular initiative.*

TEST 7 PCT(TM) Scientific data suggest ingredients in TEST 7 PCT(TM) may possess specific, dual-acting testosterone enhancing and estrogenic regulating properties.*

Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) capsule daily (in the morning) at the same time each day, or as directed by a qualified healthcare practitioner. Best if taken on a full stomach. For best results take four to eight (4-8) consecutive weeks (1-2 Cycles). An eight (8) week break between cycles is recommended.

STACKING PROTOCOL WEEK 1 WEEK 2 WEEK 3 WEEK 4 TEST 7 PCT(TM) 1 CAPSULE PER DAY 1 CAPSULE PER DAY 1 CAPSULE PER DAY 1 CAPSULE PER DAY

Precautions

Do not exceed recommended dose. Do not take for more than eight (8) consecutive weeks.

KEEP THIS PRODUCT AND ALL SUPPLEMENTS OUT OF THE REACH OF CHILDREN.

Do not take for more than eight (8) consecutive weeks.

This product should not be taken by pregnant or lactating women. Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, or thinking about becoming pregnant.

Warnings: Not intended for use by persons under age 18.

See for yourself

Test 7 PCT by Image Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Test 7 PCT by Image Sports

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

ULTRA CONCENTRATED TEST BOOSTING / PCT MATRIX(TM)

450 mg per serving

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Capsicum annuum, Magnesium Stearate, FD&C Blue No. 1, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Test 7 PCT by Image Sports Drug Interactions

Want to check YOUR meds against Test 7 PCT?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,063Drugs
1,036 Moderate 27 Minor

Ingredients driving the most interactions

Ginger 1,007
Clove 977
Safflower 208

Each ingredient & the kinds of drugs it affects

For each ingredient in Test 7 PCT with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ginger14 drug types · 1,007 drugs

Anticoagulant/Antiplatelet Drugs

Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.

Likelihood Possible Evidence D
Phenprocoumon (Marcoumar, Others)

Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.

Likelihood Possible Evidence B
Calcium Channel Blockers

Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.

Likelihood Unlikely Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Metronidazole (Flagyl)

Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.

Likelihood Possible Evidence D

Clove7 drug types · 977 drugs

Antidiabetes Drugs

Theoretically, concomitant use of clove extracts with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical and laboratory research suggest that polyphenol extracts from clove flower buds might lower blood glucose levels. Dosing adjustments for insulin or oral hypoglycemic agents may be necessary when taken with clove. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP1A2 in a dose-dependent manner,. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2C9.
In vitro research shows that eugenol, the principal constituent of clove, inhibits CYP2C9 in a dose-dependent manner. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP2D6 in a dose-dependent manner. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP3A4 in a dose-dependent manner. This effect has not been reported in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Laboratory research suggests that eugenol, a constituent of clove, has antiplatelet activity. This interaction has not been reported in humans.

Likelihood Unlikely Evidence D
Ibuprofen (Advil, Others)

Theoretically, topical application of clove oil with ibuprofen might increase the absorption and side effects of topical ibuprofen.
Laboratory research shows that topical application of clove oil increases the absorption of topical ibuprofen. This interaction has not been reported in humans.

Likelihood Possible Evidence D

Safflower3 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence B
Warfarin

Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Test 7 PCT, from the product label.

Image Sports

See all Image Sports products
Name
Image Sports
City
Fort Lauderdale
State
FL
ZipCode
33301
Pharmacist Counseling Corner

Test 7 PCT by Image Sports: Common Questions

Does Test 7 PCT by Image Sports interact with any medications?
Yes. Based on its ingredients, Test 7 PCT has a known interaction with 1,063 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Test 7 PCT contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin or another blood thinner?
You need to check with your pharmacist first. Safflower, ginger, and clove all carry a moderate risk of increasing bleeding when combined with blood thinners. There are case reports of people on warfarin whose bleeding risk increased after taking ginger or safflower, so this isn't just theoretical.
What if I'm diabetic and take insulin or diabetes pills?
All three active herbal ingredients—safflower, ginger, and clove—may lower blood sugar. Combined with your medication, this could push your blood glucose too low. Talk to your doctor about whether this product fits your regimen and whether your dose needs adjusting.
Is this safe during pregnancy?
Safflower flower may stimulate the uterus and has been used traditionally to bring on menstruation, so medicinal amounts should be avoided during pregnancy. There isn't enough reliable data on medicinal ginger or clove in pregnancy either. If you're pregnant or trying to conceive, ask your doctor or pharmacist before using this product.
Can I breastfeed while taking this?
There isn't enough reliable information on medicinal safflower or clove while breastfeeding, so they're best avoided beyond normal food use. Ginger is often considered likely safe in typical amounts, but talk to your doctor or pharmacist about this product specifically and your individual situation.
What are the most common side effects I might notice?
Ginger commonly causes mild stomach upset—heartburn, burping, diarrhea, or a pepper-like feeling in the mouth—especially at doses above 5 grams daily. Clove as a food spice is fine, but concentrated clove oil can irritate the mouth and digestive tract. Safflower in high doses has been linked to liver problems in rare cases.
How does this interact with cancer medications?
Ginger may inhibit CYP3A4, an enzyme your body uses to break down many cancer drugs. This could raise those drug levels and increase toxicity. There are a handful of case reports of this happening. If you're on cancer treatment, check with your oncologist or pharmacist before adding this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Test 7 PCT is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Test 7 PCT label
Sources

Sources & How We Checked

Test 7 PCT's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 104 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Safflower 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989;38:1314-9.. PubMed
  5. Amato, P. and Quercia, R. A. A historical perspective and review of the safety of lipid emulsion in pregnancy. Nutr Clin Pract. 1991;6(5):189-192. PubMed
  6. Demke, D. M., Peters, G. R., Linet, O. I., Metzler, C. M., and Klott, K. A. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70(1-2):73-80. PubMed
  7. Kaji, K., Yoshida, S., Nagata, N., Yamashita, T., Mizukoshi, E., Honda, M., Kojima, Y., and Kaneko, S. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878. PubMed
  8. Kwon, J. S., Snook, J. T., Wardlaw, G. M., and Hwang, D. H. Effects of diets high in saturated fatty acids, canola oil, or safflower oil on platelet function, thromboxane B2 formation, and fatty acid composition of platelet phospholipids. Am.J.Clin.Nutr. PubMed
  9. Lloyd-Still, J. D., Simon, S. H., Wessel, H. U., and Gibson, L. E. Negative effects of oral fatty acid supplementation on sweat chloride in cystic fibrosis. Pediatrics 1979;64(1):50-52. DOI
  10. Challen, A. D., Branch, W. J., and Cummings, J. H. The effect of aspirin and linoleic acid on platelet aggregation, platelet fatty acid composition and haemostasis in man. Hum Nutr Clin Nutr 1983;37(3):197-208.
  11. Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked, cro
  12. Liu Y, Liu S, Shi Y, et al. Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Xenobiotica. 2017 Oct 25:1-6. [Epub ahead of print] PubMed
  13. de Ataide EC, Reges Perales S, de Oliveira Peres MA, et al. Acute liver failure induced by Carthamus tinctorius oil: Case reports and literature review. Transplant Proc. 2018;50(2):476-477. PubMed
  14. Ruyvaran M, Zamani A, Mohamadian A, et al. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. PubMed

See these in context on the Safflower monograph →

Clove 26 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
  4. Chen SJ, Wang MH, Chen IJ. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. Gen Pharmacol 1996;27:629-33. PubMed
  5. Malson JL, Lee EM, Murty R, et al. Clove cigarette smoking: biochemical, physiological, and subjective effects. Pharmacol Biochem Behav 2003;74:739-45. PubMed
  6. Kirsch CM, Yenokida GG, Jensen WA, et al. Non-cardiogenic pulmonary oedema due to the intravenous administration of clove oil. Thorax 1990;45:235-6. PubMed
  7. Pallares, D. E. Link between clove cigarettes and urticaria? Postgrad.Med 10-1-1999;106(4):153. PubMed
  8. Barnard, D. R. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol. 1999;36(5):625-629. PubMed
  9. Sanchez-Perez, J. and Garcia-Diez, A. Occupational allergic contact dermatitis from eugenol, oil of cinnamon and oil of cloves in a physiotherapist. Contact Dermatitis 1999;41(6):346-347. PubMed
  10. Andersen, K. E., Johansen, J. D., Bruze, M., Frosch, P. J., Goossens, A., Lepoittevin, J. P., Rastogi, S., White, I., and Menne, T. The time-dose-response relationship for elicitation of contact dermatitis in isoeugenol allergic individuals. Toxicol.Appl PubMed
  11. Alqareer, A., Alyahya, A., and Andersson, L. The effect of clove and benzocaine versus placebo as topical anesthetics. J Dent 2006;34(10):747-750. PubMed
  12. Lane, B. W., Ellenhorn, M. J., Hulbert, T. V., and McCarron, M. Clove oil ingestion in an infant. Hum.Exp Toxicol. 1991;10(4):291-294. PubMed
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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