Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Trifala Supreme Ingredients & Drug Interactions

by Harmony Nutraceuticals

Trifala Supreme label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Trifala Supreme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Trifala Supreme is a dietary supplement by Harmony Nutraceuticals with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, cholesterol and heart health, immune support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Amlowin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Trifala Supreme by Harmony Nutraceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Trifala Supreme by Harmony Nutraceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Trifala Supreme by Harmony Nutraceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Blend” is a proprietary blend — the label gives one combined amount (1,200 mg) without saying how much of each component you get.

Trifala Supreme contains 3 active ingredients. The one we have data on is Indian gooseberry (Amlowin), a fruit used traditionally for digestive and cholesterol support.

The product also includes Haritawin and Bibhitaki Fruit Extract, both part of the traditional Trifala blend, but we hold limited monograph data on those two. The capsule itself is vegan.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: vision, weight loss, digestion, detoxification and longevity.
  • We looked for evidence on: Obesity, Dyslipidemia, Hypercholesterolemia, Cardiovascular disease (CVD), Diabetes, Metabolic syndrome — and 3 related terms.
  • The strongest evidence on file: Indian Gooseberry is rated "Possibly Effective" for Dyslipidemia (Natural Medicines).
  • Also on file: Indian Gooseberry is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Diabetes, Hypercholesterolemia, Obesity, and more.

Indian gooseberry is possibly effective for acid reflux (GERD) and high cholesterol (dyslipidemia) based on available evidence. For male-pattern baldness (androgenic alopecia), the evidence is insufficient to rate it one way or the other.

We don't have effectiveness ratings on file for Haritawin or Bibhitaki Fruit Extract, so we can't speak to what they may do in this formula.

The evidence, ingredient by ingredient Indian Gooseberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Indian gooseberry is generally well tolerated as a food, but safety data at supplement doses is less studied. During pregnancy, there isn't enough reliable safety information — it's best to avoid it in pregnancy.

During breastfeeding, safety data is too limited, so we advise against it. In clinical trials, a small number of people reported stomach discomfort or upset stomach, one reported fatigue, and three reported muscle or joint pain.

We don't have safety information on file for Haritawin or Bibhitaki Fruit Extract.

Side effects, ingredient by ingredient Indian Gooseberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Trifala Supreme, double-check if you're on blood thinners (anticoagulants), antiplatelet drugs like clopidogrel or aspirin, or diabetes medications. Indian gooseberry can increase bleeding risk and lower blood sugar — both Moderate severity concerns.

No interactions are documented for Haritawin or Bibhitaki Fruit Extract, as we could not check them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Trifala Supreme may appeal to you if you're interested in traditional digestive or cholesterol support and don't take blood thinners or diabetes medications. If you're on any blood thinner, antiplatelet drug, or diabetes medication, check with your pharmacist first — Indian gooseberry can change how these work.

Pregnant or breastfeeding? Talk to your doctor before starting this one.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Trifala Supreme, straight from the product label.

Brand Harmony Nutraceuticals
Barcode (UPC) 817339020575
Net contents 120 Vegan Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 333383
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Trifala Supreme by Harmony Nutraceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
817339020575
IngredientAmount% DV
Blend1200 mg--
Amlowin0 NP--
Haritawin0 NP--
Bibhitaki Fruit Extract0 NP--

Other ingredients: Vegan Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Trifala is a synergistic combination of three superfruits that supports vision, weight loss, and longevity. This gentle laxative aids digestion, elimination, and detoxification. Trifala's rejuvenating and antioxidant properties enhance the functions of the circulatory, urinary, and respiratory systems. It protects cells from the damaging effects of free radicals.* It is Ayurveda's most important and universally used formula.

V Vegan

Harmonious and Sustainable Clinical Grade GMP Certified Certified Lab Tested

Gastrointestinal Harmony Cellular Detox Made with Love in the USA

Nothing else, Pure goodness!

Suggested/Recommended/Usage/Directions

Suggested use: 1-2 capsules, once or twice daily with, or before meals or as directed by your healthcare practitioner.

Precautions

Caution: Keep out of reach of children.

Do not use if inner seal is missing or broken.

Pregnant and nursing women, individuals taking medications or persons with a health condition should consult their healthcare professional before using this product.

Storage

Protect from heat, light, and moisture.

Seals/Symbols

GMP Certified Good Manufacturing GMP Certified Facility Eco-Friendly O-K! V Vegan

Formula

Halal

Kosher

FDA Statement of Identity

Pure Herbal Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Amlowin and Haritawin are trademarks of Harmony Nutraceuticals, LLC

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Trifala Supreme by Harmony Nutraceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Trifala Supreme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Trifala Supreme by Harmony Nutraceuticals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Blend

1200 mg per serving
  • › Amlowin
  • › Haritawin
  • › Bibhitaki Fruit Extract

Other (inactive) ingredients: Vegan Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Trifala Supreme by Harmony Nutraceuticals Drug Interactions

Want to check YOUR meds against Trifala Supreme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Amlowin 208

Individual Drug Interactions

The ingredients in Trifala Supreme interact with 208 drugs. Click any drug to see the details.

1 of the 3 ingredients in Trifala Supreme interact with drugs. Each result below shows which ingredient is responsible. Amlowin

Each ingredient & the kinds of drugs it affects

For each ingredient in Trifala Supreme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Amlowin4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
Amlowin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Trifala Supreme, from the product label.

Harmony Nutraceuticals

See all Harmony Nutraceuticals products
Name
Harmony Nutraceuticals, LLC
Street Address
3701 NW 62nd Street
City
OKC
State
OK
ZipCode
73112
Phone Number
(405) 601-4518
Web Address
www.HarmonyVeda.com
Pharmacist Counseling Corner

Trifala Supreme by Harmony Nutraceuticals: Common Questions

Does Trifala Supreme by Harmony Nutraceuticals interact with any medications?
Yes. Based on its ingredients, Trifala Supreme has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Trifala Supreme contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually work for reflux or cholesterol?
Indian gooseberry, the ingredient we have data on, is possibly effective for acid reflux and high cholesterol. That means there's some evidence, but it's not definitive. We don't have effectiveness ratings for the other two ingredients in the blend.
Is it safe during pregnancy?
No — there isn't enough reliable safety information during pregnancy, so it's best to avoid it. Talk with your doctor if you're pregnant or planning to be.
What side effects showed up in trials?
A small number of people reported stomach discomfort or upset stomach. One person reported fatigue, and three reported muscle or joint pain. These are rare, but worth knowing.
Can I take this if I'm breastfeeding?
Safety data during breastfeeding is too limited, so we advise against it. Check with your doctor or pharmacist for personalized advice based on your situation.
What's in this blend — is it just one herb?
No, it's three ingredients. We have interaction and safety data for Indian gooseberry (Amlowin), but we hold limited monograph information for Haritawin and Bibhitaki Fruit Extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Trifala Supreme is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Trifala Supreme label
Go deeper

The Full Monographs Behind Trifala Supreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph →
Sources

Sources & How We Checked

Trifala Supreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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